KinOrtho: a method for mapping human kinase orthologs across the tree of life and illuminating understudied kinases LC Huang, R Taujale, N Gravel, A Venkat, W Yeung, DP Byrne, PA Eyers, ... BMC bioinformatics 22, 1-25, 2021 | 11 | 2021 |
Phosformer: an explainable transformer model for protein kinase-specific phosphorylation predictions Z Zhou, W Yeung, N Gravel, M Salcedo, S Soleymani, S Li, N Kannan Bioinformatics 39 (2), btad046, 2023 | 8 | 2023 |
Dark kinase annotation, mining, and visualization using the Protein Kinase Ontology S Soleymani, N Gravel, LC Huang, W Yeung, E Bozorgi, NG Bendzunas, ... PeerJ 11, e16087, 2023 | 4 | 2023 |
Tree visualizations of protein sequence embedding space enable improved functional clustering of diverse protein superfamilies W Yeung, Z Zhou, L Mathew, N Gravel, R Taujale, B O’Boyle, M Salcedo, ... Briefings in Bioinformatics 24 (1), bbac619, 2023 | 4 | 2023 |
Modularity of the hydrophobic core and evolution of functional diversity in fold A glycosyltransferases A Venkat, D Tehrani, R Taujale, W Yeung, N Gravel, KW Moremen, ... Journal of Biological Chemistry 298 (8), 2022 | 4 | 2022 |
XAI meets Biology: A Comprehensive Review of Explainable AI in Bioinformatics Applications Z Zhou, M Hu, M Salcedo, N Gravel, W Yeung, A Venkat, D Guo, J Zhang, ... arXiv preprint arXiv:2312.06082, 2023 | 3 | 2023 |
Mechanistic and evolutionary insights into isoform-specific ‘supercharging’in DCLK family kinases A Venkat, G Watterson, DP Byrne, B O'Boyle, S Shrestha, N Gravel, ... Elife 12, RP87958, 2023 | 2 | 2023 |
Predicting protein and pathway associations for understudied dark kinases using pattern-constrained knowledge graph embedding MV Salcedo, N Gravel, A Keshavarzi, LC Huang, KJ Kochut, N Kannan PeerJ 11, e15815, 2023 | 1 | 2023 |
Using explainable machine learning to uncover the kinase–substrate interaction landscape Z Zhou, W Yeung, S Soleymani, N Gravel, M Salcedo, S Li, N Kannan Bioinformatics 40 (2), btae033, 2024 | | 2024 |
Informatic challenges and advances in illuminating the druggable proteome ER Taujal, N Gravel, Z Zhou, W Yeung, K Kochut, N Kannan Drug Discovery Today, 103894, 2024 | | 2024 |
An explainable unsupervised framework for alignment-free protein classification using sequence embeddings W Yeung, Z Zhou, L Mathew, N Gravel, R Taujale, A Venkat, W Lanzilotta, ... bioRxiv, 2022.02. 08.478871, 2022 | | 2022 |
Hydrophobic core variations distinguishing mechanistic divergence of fold a glycosyltransferases A Venkat, R Taujale, W Yeung, N Gravel, K Moremen, N Kannan, ... GLYCOBIOLOGY 31 (12), 1751-1752, 2021 | | 2021 |