Quantitative imaging of gut microbiota spatial organization KA Earle, G Billings, M Sigal, JS Lichtman, GC Hansson, JE Elias, ... Cell host & microbe 18 (4), 478-488, 2015 | 459 | 2015 |
Helicobacter pylori activates and expands Lgr5+ stem cells through direct colonization of the gastric glands M Sigal, ME Rothenberg, CY Logan, JY Lee, RW Honaker, RL Cooper, ... Gastroenterology 148 (7), 1392-1404. e21, 2015 | 248 | 2015 |
Stromal R-spondin orchestrates gastric epithelial stem cells and gland homeostasis M Sigal, CY Logan, M Kapalczynska, HJ Mollenkopf, H Berger, ... Nature 548 (7668), 451-455, 2017 | 210 | 2017 |
Chemodetection and destruction of host urea allows Helicobacter pylori to locate the epithelium JY Huang, EG Sweeney, M Sigal, HC Zhang, SJ Remington, MA Cantrell, ... Cell host & microbe 18 (2), 147-156, 2015 | 189 | 2015 |
R-spondin 3 promotes stem cell recovery and epithelial regeneration in the colon C Harnack, H Berger, A Antanaviciute, R Vidal, S Sauer, A Simmons, ... Nature communications 10 (1), 4368, 2019 | 121 | 2019 |
Genomic aberrations after short-term exposure to colibactin-producing E. coli transform primary colon epithelial cells A Iftekhar, H Berger, N Bouznad, J Heuberger, F Boccellato, U Dobrindt, ... Nature communications 12 (1), 1003, 2021 | 119 | 2021 |
Helicobacter pylori depletes cholesterol in gastric glands to prevent interferon gamma signaling and escape the inflammatory response P Morey, L Pfannkuch, E Pang, F Boccellato, M Sigal, A Imai-Matsushima, ... Gastroenterology 154 (5), 1391-1404. e9, 2018 | 117 | 2018 |
R-spondin-3 induces secretory, antimicrobial Lgr5+ cells in the stomach M Sigal, MM Reines, S Müllerke, C Fischer, M Kapalczynska, H Berger, ... Nature cell biology 21 (7), 812-823, 2019 | 71 | 2019 |
Epithelial response to IFN‐γ promotes SARS‐CoV‐2 infection J Heuberger, J Trimpert, D Vladimirova, C Goosmann, M Lin, R Schmuck, ... EMBO molecular medicine 13 (4), e13191, 2021 | 70 | 2021 |
The role of Wnt and R-spondin in the stomach during health and disease AS Fischer, M Sigal Biomedicines 7 (2), 44, 2019 | 34 | 2019 |
The role of microbiota in primary sclerosing cholangitis and related biliary malignancies B Özdirik, T Müller, A Wree, F Tacke, M Sigal International Journal of Molecular Sciences 22 (13), 6975, 2021 | 31 | 2021 |
Stem cells, helicobacter pylori, and mutational landscape: utility of preclinical models to understand carcinogenesis and to direct management of gastric cancer D Liabeuf, M Oshima, DE Stange, M Sigal Gastroenterology 162 (4), 1067-1087, 2022 | 28 | 2022 |
BMP feed-forward loop promotes terminal differentiation in gastric glands and is interrupted by H. pylori-driven inflammation M Kapalczynska, M Lin, J Maertzdorf, J Heuberger, S Muellerke, X Zuo, ... Nature communications 13 (1), 1577, 2022 | 24 | 2022 |
High Yap and Mll1 promote a persistent regenerative cell state induced by Notch signaling and loss of p53 J Heuberger, J Grinat, F Kosel, L Liu, S Kunz, RO Vidal, M Keil, ... Proceedings of the National Academy of Sciences 118 (22), e2019699118, 2021 | 21 | 2021 |
Defence and adaptation mechanisms of the intestinal epithelium upon infection A Iftekhar, M Sigal International Journal of Medical Microbiology 311 (3), 151486, 2021 | 21 | 2021 |
Gastric stem cells promote inflammation and gland remodeling in response to Helicobacter pylori via Rspo3‐Lgr4 axis J Wizenty, S Müllerke, M Kolesnichenko, J Heuberger, M Lin, AS Fischer, ... The EMBO Journal 41 (13), e109996, 2022 | 20 | 2022 |
Darbepoetin-α inhibits the perpetuation of necro-inflammation and delays the progression of cholestatic fibrosis in mice M Sigal, N Siebert, D Zechner, E Menschikow, K Abshagen, B Vollmar, ... Laboratory investigation 90 (10), 1447-1456, 2010 | 20 | 2010 |
Aktualisierte S2k-Leitlinie Helicobacterpylori und gastroduodenale Ulkuskrankheit der Deutschen Gesellschaft für Gastroenterologie, Verdauungs-und Stoffwechselkrankheiten (DGVS … W Fischbach, J Bornschein, JC Hoffmann, S Koletzko, A Link, L Macke, ... Zeitschrift für Gastroenterologie 61 (05), 544-606, 2023 | 18 | 2023 |
Microbe-driven genotoxicity in gastrointestinal carcinogenesis K Hartl, M Sigal International Journal of Molecular Sciences 21 (20), 7439, 2020 | 18 | 2020 |
Coevolution between the human microbiota and the epithelial immune system M Sigal, TF Meyer Digestive Diseases 34 (3), 190-193, 2016 | 18 | 2016 |