Alpha‐synuclein aggregates activate calcium pump SERCA leading to calcium dysregulation C Betzer, LB Lassen, A Olsen, RH Kofoed, L Reimer, E Gregersen, ... EMBO reports 19 (5), e44617, 2018 | 105 | 2018 |
ELISA method to detect α-synuclein oligomers in cell and animal models LB Lassen, E Gregersen, AK Isager, C Betzer, RH Kofoed, PH Jensen PloS one 13 (4), e0196056, 2018 | 66 | 2018 |
Focused ultrasound as a novel strategy for noninvasive gene delivery to retinal Müller glia Y Touahri, R Dixit, RH Kofoed, K Mikloska, EJ Park, R Raeisossadati, ... Theranostics 10 (7), 2982, 2020 | 26 | 2020 |
Strategy to enhance transgene expression in proximity of amyloid plaques in a mouse model of Alzheimer's disease D Weber-Adrian, RH Kofoed, JWY Chan, J Silburt, Z Noroozian, S Kügler, ... Theranostics 9 (26), 8127, 2019 | 25 | 2019 |
Inflammation kinase PKR phosphorylates α-synuclein and causes α-synuclein-dependent cell death L Reimer, LB Vesterager, C Betzer, J Zheng, LD Nielsen, RH Kofoed, ... Neurobiology of disease 115, 17-28, 2018 | 24 | 2018 |
PKR kinase directly regulates tau expression and Alzheimer's disease‐related tau phosphorylation L Reimer, C Betzer, RH Kofoed, C Volbracht, K Fog, C Kurhade, E Nilsson, ... Brain Pathology 31 (1), 103-119, 2021 | 23 | 2021 |
Polo-like kinase 2 modulates α-synuclein protein levels by regulating its mRNA production RH Kofoed, J Zheng, N Ferreira, S Lykke-Andersen, M Salvi, C Betzer, ... Neurobiology of disease 106, 49-62, 2017 | 22 | 2017 |
Ultrasound delivery of a TrkA agonist confers neuroprotection to Alzheimer-associated pathologies K Xhima, K Markham-Coultes, R Hahn Kofoed, HU Saragovi, K Hynynen, ... Brain 145 (8), 2806-2822, 2022 | 21 | 2022 |
Efficacy of gene delivery to the brain using AAV and ultrasound depends on serotypes and brain areas RH Kofoed, CL Dibia, K Noseworthy, K Xhima, N Vacaresse, K Hynynen, ... Journal of Controlled Release 351, 667-680, 2022 | 19 | 2022 |
Systemic AAV6-synapsin-GFP administration results in lower liver biodistribution, compared to AAV1&2 and AAV9, with neuronal expression following ultrasound-mediated brain delivery D Weber-Adrian, RH Kofoed, J Silburt, Z Noroozian, K Shah, A Burgess, ... Scientific Reports 11 (1), 1934, 2021 | 14 | 2021 |
Glycogen synthase kinase 3 β activity is essential for Polo-like kinase 2-and Leucine-rich repeat kinase 2-mediated regulation of α-synuclein RH Kofoed, C Betzer, N Ferreira, PH Jensen Neurobiology of Disease 136, 104720, 2020 | 14 | 2020 |
Transgene distribution and immune response after ultrasound delivery of rAAV9 and PHP. B to the brain in a mouse model of amyloidosis RH Kofoed, S Heinen, J Silburt, S Dubey, CL Dibia, M Maes, EM Simpson, ... Molecular Therapy-Methods & Clinical Development 23, 390-405, 2021 | 12 | 2021 |
Viral alpha-synuclein knockdown prevents spreading synucleinopathy S Menon, RH Kofoed, F Nabbouh, K Xhima, Y Al-Fahoum, T Langman, ... Brain Communications 3 (4), fcab247, 2021 | 9 | 2021 |
Investigation of RNA synthesis using 5-bromouridine labelling and immunoprecipitation RH Kofoed, C Betzer, S Lykke-Andersen, E Molska, PH Jensen JoVE (Journal of Visualized Experiments), e57056, 2018 | 6 | 2018 |
The engineered AAV2-HBKO promotes non-invasive gene delivery to large brain regions beyond ultrasound targeted sites RH Kofoed, K Noseworthy, K Wu, S Sivadas, L Stanek, B Elmer, ... Molecular Therapy-Methods & Clinical Development 27, 167-184, 2022 | 5 | 2022 |
Using focused ultrasound to modulate microglial structure and function S Grewal, E Gonçalves de Andrade, RH Kofoed, PM Matthews, I Aubert, ... Frontiers in Cellular Neuroscience 17, 1290628, 2023 | 1 | 2023 |
Sonoselective delivery using ultrasound and microbubbles combined with intravenous rAAV9 CLDN5-GFP does not increase endothelial gene expression RH Kofoed, EM Simpson, K Hynynen, I Aubert Gene Therapy 30 (12), 807-811, 2023 | 1 | 2023 |
The Impact of Serotypes and Anatomical Regions on the Efficacy of Focused Ultrasound-Mediated AAV Delivery to the Brain RH Kofoed, K Noseworthy, C Dibia, N Vacaresse, K Hynynen, I Aubert MOLECULAR THERAPY 29 (4), 180-180, 2021 | 1 | 2021 |
The Use of Co-immunoprecipitation to Study Conformation-Specific Protein Interactions of Oligomeric α-Synuclein Aggregates C Betzer, RH Kofoed, PH Jensen Co-Immunoprecipitation Methods for Brain Tissue, 23-36, 2019 | 1 | 2019 |
Science around the world P Antas, A Cleveland, P Contessotto, R Schaffrath Trends in molecular medicine, 2024 | | 2024 |