Collision induced unfolding of intact antibodies: rapid characterization of disulfide bonding patterns, glycosylation, and structures Y Tian, L Han, AC Buckner, BT Ruotolo Analytical chemistry 87 (22), 11509-11515, 2015 | 179 | 2015 |
Collisional and Coulombic unfolding of gas‐phase proteins: high correlation to their domain structures in solution Y Zhong, L Han, BT Ruotolo Angewandte Chemie 126 (35), 9363-9366, 2014 | 164 | 2014 |
Bound anions differentially stabilize multiprotein complexes in the absence of bulk solvent L Han, SJ Hyung, JJS Mayers, BT Ruotolo Journal of the American Chemical Society 133 (29), 11358-11367, 2011 | 114 | 2011 |
Bound cations significantly stabilize the structure of multiprotein complexes in the gas-phase L Han, SJ Hyung, BT Ruotolo Angewandte Chemie (International ed. in English) 51 (23), 5692, 2012 | 71 | 2012 |
High-throughput multi-attribute analysis of antibody-drug conjugates enabled by trapped ion mobility spectrometry and top-down mass spectrometry EJ Larson, DS Roberts, JA Melby, KM Buck, Y Zhu, S Zhou, L Han, ... Analytical chemistry 93 (29), 10013-10021, 2021 | 33 | 2021 |
Ion mobility-mass spectrometry differentiates protein quaternary structures formed in solution and in electrospray droplets L Han, BT Ruotolo Analytical chemistry 87 (13), 6808-6813, 2015 | 30 | 2015 |
Hofmeister salts recover a misfolded multiprotein complex for subsequent structural measurements in the gas phase L Han, BT Ruotolo Angewandte Chemie (International ed. in English) 52 (32), 8329, 2013 | 28 | 2013 |
Traveling-wave ion mobility-mass spectrometry reveals additional mechanistic details in the stabilization of protein complex ions through tuned salt additives L Han, BT Ruotolo International Journal for Ion Mobility Spectrometry 16, 41-50, 2013 | 28 | 2013 |
Synthesis, characterization, DNA-binding and DNA-photocleavage studies of [Ru (bpy) 2 (pmip)] 2+ and [Ru (phen) 2 (pmip)] 2+(pmip= 2-(2′-pyrimidyl) imidazo [4, 5-f][1, 10 … S Shi, T Xie, TM Yao, CR Wang, XT Geng, DJ Yang, LJ Han, LN Ji Polyhedron 28 (7), 1355-1361, 2009 | 28 | 2009 |
Automated capillary isoelectric focusing-mass spectrometry with ultrahigh resolution for characterizing microheterogeneity and isoelectric points of intact protein complexes T Xu, L Han, L Sun Analytical Chemistry 94 (27), 9674-9682, 2022 | 25 | 2022 |
Analysis of a Soluble (UreD:UreF:UreG)2 Accessory Protein Complex and Its Interactions with Klebsiella aerogenes Urease by Mass Spectrometry MA Farrugia, L Han, Y Zhong, JL Boer, BT Ruotolo, RP Hausinger Journal of The American Society for Mass Spectrometry 24 (9), 1328-1337, 2013 | 21 | 2013 |
Dramatically stabilizing multiprotein complex structure in the absence of bulk water using tuned Hofmeister salts L Han, SJ Hyung, BT Ruotolo Faraday discussions 160, 371-388, 2013 | 21 | 2013 |
An improved capillary isoelectric focusing-mass spectrometry method for high-resolution characterization of monoclonal antibody charge variants T Xu, L Han, AMG Thompson, L Sun Analytical Methods 14 (4), 383-393, 2022 | 16 | 2022 |
Rapid analysis of reduced antibody drug conjugate by online LC-MS/MS with fourier transform Ion cyclotron resonance mass spectrometry EJ Larson, Y Zhu, Z Wu, B Chen, Z Zhang, S Zhou, L Han, Q Zhang, Y Ge Analytical chemistry 92 (22), 15096-15103, 2020 | 11 | 2020 |
Impact of linker-drug on ion exchange chromatography separation of antibody-drug conjugates Z Zhang, S Zhou, L Han, Q Zhang, WA Pritts Mabs 11 (6), 1113-1121, 2019 | 10 | 2019 |
Flavonoids inhibit heparin-induced aggregation of the third repeat (r3) of microtubule-binding domain of alzheimer’s tau protein LJ Han, S Shi, LF Zheng, DJ Yang, TM Yao, LN Ji Bulletin of the Chemical Society of Japan 83 (8), 911-922, 2010 | 10 | 2010 |
Selective Reduction of Cysteine Mutant Antibodies for Site-Specific Antibody–Drug Conjugates X Liao, A Haight, D Welch, L Han Bioconjugate Chemistry 34 (12), 2293-2301, 2023 | 2 | 2023 |
Conjugation Site Analysis by MS/MS Protein Sequencing L Han, Y Zhao, Q Zhang Antibody-Drug Conjugates: Methods and Protocols, 221-233, 2020 | 2 | 2020 |
Developing Ion Mobility-Mass Spectrometry for Measurements of Solution-Relevant Protein Structures. L Han | | 2014 |