The imidazodiazepine, KRM-II-81: an example of a newly emerging generation of GABAkines for neurological and psychiatric disorders JM Witkin, A Lippa, JL Smith, X Jin, X Ping, A Biggerstaff, BM Kivell, ... Pharmacology Biochemistry and Behavior 213, 173321, 2022 | 27 | 2022 |
Bisindole Alkaloids from the Alstonia Species: Recent Isolation, Bioactivity, Biosynthesis, and Synthesis KP Pandey, MT Rahman, JM Cook Molecules 26 (11), 3459, 2021 | 16 | 2021 |
Clinical investigations of compounds targeting metabotropic glutamate receptors JM Witkin, KP Pandey, JL Smith Pharmacology Biochemistry and Behavior 219, 173446, 2022 | 13 | 2022 |
Rationalizing the binding and α subtype selectivity of synthesized imidazodiazepines and benzodiazepines at GABAA receptors by using molecular docking studies LK Golani, MY Mian, T Ahmed, KP Pandey, P Mondal, D Sharmin, ... Bioorganic & Medicinal Chemistry Letters 62, 128637, 2022 | 7 | 2022 |
Design, synthesis and characterization of novel gamma‑aminobutyric acid type A receptor ligands KP Pandey, MZA Khan, LK Golani, P Mondal, MY Mian, F Rashid, ... ARKIVOC: free online journal of organic chemistry 2020 (Pt 7), 242, 2020 | 6 | 2020 |
Metabolism, pharmacokinetics, and anticonvulsant activity of a deuterated analog of the α2/3‐selective GABAkine KRM‐II‐81 LK Golani, B Divović, D Sharmin, KP Pandey, MY Mian, R Cerne, ... Biopharmaceutics & Drug Disposition 43 (2), 66-75, 2022 | 4 | 2022 |
Structural analogs of the GABAkine KRM-II-81 are orally bioavailable anticonvulsants without sedation KP Pandey, B Divović, F Rashid, LK Golani, NM Zahn, MJ Meyer, ... Journal of Pharmacology and Experimental Therapeutics 385 (1), 50-61, 2023 | 2 | 2023 |
Hydrochloride salt of the GABAkine KRM-II-81 MY Mian, B Divović, D Sharmin, KP Pandey, LK Golani, ... ACS omega 7 (31), 27550-27559, 2022 | 2 | 2022 |
Comparative anticonvulsant activity of the GABAkine KRM‐II‐81 and a deuterated analog X Ping, MJ Meyer, NM Zahn, LK Golani, D Sharmin, KP Pandey, ... Drug development research 84 (3), 601-605, 2023 | 1 | 2023 |
Completion of the Total Synthesis of Several Bioactive Sarpagine/Macroline Alkaloids including the Important NF-κB Inhibitor N4-Methyltalpinine MT Rahman, VVNPB Tiruveedhula, MR Stephen, SK Rallapalli, ... Molecules 27 (5), 1738, 2022 | 1 | 2022 |
New Imidazodiazepine Analogue, 5-(8-Bromo-6-(pyridin-2-yl)-4H-benzo[f]imidazo[1,5-a][1,4]diazepin-3-yl)oxazole, Provides a Simplified Synthetic Scheme, High … D Sharmin, B Divović, X Ping, R Cerne, JL Smith, S Rezvanian, P Mondal, ... ACS Chemical Neuroscience 15 (3), 517-526, 2024 | | 2024 |
Vascular effects of midazolam, flumazenil, and a novel imidazobenzodiazepine MP-III-058 on isolated rat aorta MG Bojić, M Treven, KP Pandey, VVNPB Tiruveedhula, A Santrač, ... Canadian Journal of Physiology and Pharmacology, 2023 | | 2023 |
Part I Enantiospecific Total Synthesis of Unnatural Enantiomers of C-19 Methylated Sarpagine/Macroline/Ajmaline-Type Biologically Active Indole Alkaloids via the Pictet … KP Pandey | | 2023 |
Better than Xanax (Chapter 5) JM Witkin, H Shafique, A Lippa, KP Pandey, JL Smith, and Cerne, Rok. Advances in health and diseases 61, 2022 | | 2022 |
Synthesis of analogs of KRM-II-81, Gamma Aminobutyric Acid Type A (GABAA) Receptor α2/α3 Subtype-selective Ligand, for Epilepsy Treatment without any adverse effects KP Pandey, JM Witkin, LK Golani, MY Mian, P Mondal, ... American Chemical Society National Meeting and Exposition Fall-2022, Chicago …, 2022 | | 2022 |
Synthesis and biological activity of a novel compound to treat psychological disorders and memory reduction P MONDAL, Y Mian, KP Pandey, D Sharmin, S Rezvanian, DE Knutson, ... American Chemical Society SciMeetings 3 (2), 2022 | | 2022 |
Positive allosteric modulation at GABAA receptor effects on symptomatic and neurotrophic in a mouse model of chronic stress S Rezvanian, P Mondal, D Sharmin, KP Pandey, A Bernardo, P Lee, ... American Chemical Society National Meeting and Exposition-Chicago, IL, USA …, 2022 | | 2022 |
Design, synthesis, and characterization of novel analogs of clinically progressing gamma-aminobutyric acid type A (GABAA) receptor α2/α3 subtype-selective ligand KRM-II-81 for … KP Pandey, JM Witkin, LK Golani, MY Mian, P Mondal, ... American Chemical Society National Meeting and Exposition-San Diego, USA …, 2022 | | 2022 |
GL-I-54, a Non-selective α2/3/5-GABAA receptor positive allosteric modulator shows disease modifying effects in chronic stress of mouse models S Rezvanian, F Rashid, MY Mian, D Sharmin, P Mondal, K Pandey, ... American Chemical Society National Meeting and Exposition-San Diego, CA, USA …, 2022 | | 2022 |
Synthesis of ligands capable of binding to a GABAA receptor as a treatment for psychological disorders P Mondal, Y Mian, KP Pandey, D Sharmin, T Prevot, T Tomoda, ... American Chemical Society-National Meeting and Exposition, Atlanta, Georgia …, 2021 | | 2021 |