| CRISPR-Cas9 in vivo gene editing for transthyretin amyloidosis JD Gillmore, E Gane, J Taubel, J Kao, M Fontana, ML Maitland, J Seitzer, ... New England Journal of Medicine 385 (6), 493-502, 2021 | 1009 | 2021 |
| A highly durable RNAi therapeutic inhibitor of PCSK9 K Fitzgerald, S White, A Borodovsky, BR Bettencourt, A Strahs, V Clausen, ... New England Journal of Medicine 376 (1), 41-51, 2017 | 714 | 2017 |
| Novel antisense therapy targeting microRNA-132 in patients with heart failure: results of a first-in-human Phase 1b randomized, double-blind, placebo-controlled study J Täubel, W Hauke, S Rump, J Viereck, S Batkai, J Poetzsch, L Rode, ... European heart journal 42 (2), 178-188, 2021 | 234 | 2021 |
| Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of Single Rising TAK-438 (Vonoprazan) Doses in Healthy Male Japanese/non-Japanese Subjects TJ Sakurai Y, Nishimura A, Kennedy G, Hibberd M, Jenkins R, Okamoto H ... Clin Transl Gastroenterol., 2015 | 169* | 2015 |
| The effects of oral doses of lansoprazole and omeprazole on gastric pH KG Tolman, SW Sanders, KN Buchi, MD Karol, DE Jennings, GL Ringham Journal of clinical gastroenterology 24 (2), 65-70, 1997 | 116 | 1997 |
| Lamotrigine does not prolong QTc in a thorough QT/QTc study in healthy subjects R Dixon, S Job, R Oliver, D Tompson, JG Wright, K Maltby, U Lorch, ... British journal of clinical pharmacology 66 (3), 396-404, 2008 | 113 | 2008 |
| Shortening of the QT interval after food can be used to demonstrate assay sensitivity in thorough QT studies J Taubel, AH Wong, A Naseem, G Ferber, AJ Camm The Journal of Clinical Pharmacology 52 (10), 1558-1565, 2012 | 78 | 2012 |
| The effects of steady‐state erythromycin and azithromycin on the pharmacokinetics of sildenafil in healthy volunteers GJ Muirhead, S Faulkner, JA Harness, J Taubel British journal of clinical pharmacology 53, 37S-43S, 2002 | 78 | 2002 |
| Zilebesiran, an RNA interference therapeutic agent for hypertension AS Desai, DJ Webb, J Taubel, S Casey, Y Cheng, GJ Robbie, D Foster, ... New England Journal of Medicine 389 (3), 228-238, 2023 | 70 | 2023 |
| Thorough QT study of the effect of oral moxifloxacin on QTc interval in the fed and fasted state in healthy Japanese and Caucasian subjects J Taubel, G Ferber, U Lorch, V Batchvarov, I Savelieva, AJ Camm British Journal of Clinical Pharmacology 77 (1), 170-179, 2014 | 52 | 2014 |
| Thorough QT study of the effect of intravenous amisulpride on QTc interval in Caucasian and Japanese healthy subjects J Täubel, G Ferber, G Fox, S Fernandes, U Lorch, AJ Camm British journal of clinical pharmacology 83 (2), 339-348, 2017 | 49 | 2017 |
| Bupivacaine extended release liposome injection does not prolong QTc interval in a thorough QT/QTc study in healthy volunteers A Naseem, T Harada, D Wang, R Arezina, U Lorch, E Onel, AJ Camm, ... The Journal of Clinical Pharmacology 52 (9), 1441-1447, 2012 | 48 | 2012 |
| Effects on 24-hour intragastric pH: a comparison of lansoprazole administered nasogastrically in apple juice and pantoprazole administered intravenously J Freston, YL Chiu, WJ Pan, N Lukasik, J Täubel Official journal of the American College of Gastroenterology| ACG 96 (7 …, 2001 | 48 | 2001 |
| Levofloxacin can be used effectively as a positive control in thorough QT/QTc studies in healthy volunteers J Taubel, A Naseem, T Harada, D Wang, R Arezina, U Lorch, AJ Camm British journal of clinical pharmacology 69 (4), 391-400, 2010 | 42 | 2010 |
| The suppression of gastro‐oesophageal reflux by alginates PW Dettmar, FC Hampson, J Taubel, U Lorch, LM Johnstone, J Sykes, ... International journal of clinical practice 61 (10), 1654-1662, 2007 | 34 | 2007 |
| A comparison of simplified lansoprazole suspension administered nasogastrically and pantoprazole administered intravenously: effects on 24‐h intragastric pH JJ Täubel, VK Sharma, YL Chiu, NL Lukasik, BL Pilmer, WJ Pan Alimentary pharmacology & therapeutics 15 (11), 1807-1817, 2001 | 30 | 2001 |
| Insulin at normal physiological levels does not prolong QTc interval in thorough QT studies performed in healthy volunteers J Taubel, U Lorch, G Ferber, J Singh, VN Batchvarov, I Savelieva, ... British journal of clinical pharmacology 75 (2), 392-403, 2013 | 29 | 2013 |
| Comparison of the effects of single and repeated oral doses of lansoprazole and rabeprazole on ambulatory 24-hour intragastric pH in healthy volunteers KG Tolman, J Täubel, S Warrington, YL Chiu, BL Pilmer, WJ Pan Clinical drug investigation 26, 21-28, 2006 | 28 | 2006 |
| Crispr-Cas9 JD Gillmore, E Gane, J Taubel, J Kao, M Fontana, ML Maitland, J Seitzer, ... vivo, 2021 | 27 | 2021 |
| Dose-related reductions in blood pressure with a RNA interference (RNAi) therapeutic targeting angiotensinogen in hypertensive patients: interim results from a first-in-human … SA Huang, J Taubel, G Fiore, P Dewland, GL Bakris, AS Desai, Y Cheng, ... Circulation 142 (Suppl_3), A14387-A14387, 2020 | 24 | 2020 |
Ulrike LorchMedical Director, Richmond PharmacologyVerified email at richmondpharmacology.com
