The expanded CAG repeat in the huntingtin gene as target for therapeutic RNA modulation throughout the HD mouse brain NA Datson, A González-Barriga, E Kourkouta, R Weij, J van de Giessen, ... PLoS One 12 (2), e0171127, 2017 | 60 | 2017 |
Design and analysis of effects of triplet repeat oligonucleotides in cell models for myotonic dystrophy A González-Barriga, SAM Mulders, J Van De Giessen, JD Hooijer, S Bijl, ... Molecular Therapy-Nucleic Acids 2, 2013 | 49 | 2013 |
Suppression of mutant protein expression in SCA3 and SCA1 mice using a CAG repeat-targeting antisense oligonucleotide E Kourkouta, R Weij, A González-Barriga, M Mulder, R Verheul, S Bosgra, ... Molecular Therapy-Nucleic Acids 17, 601-614, 2019 | 42 | 2019 |
A low absolute number of expanded transcripts is involved in myotonic dystrophy type 1 manifestation in muscle AEEG Gudde, A González-Barriga, WJAA van den Broek, B Wieringa, ... Human molecular genetics 25 (8), 1648-1662, 2016 | 38 | 2016 |
Cell membrane integrity in myotonic dystrophy type 1: implications for therapy A Gonzalez-Barriga, J Kranzen, HJE Croes, S Bijl, WJAA van den Broek, ... PLoS One 10 (3), e0121556, 2015 | 27 | 2015 |
Intracellular Distribution and Nuclear Activity of Antisense Oligonucleotides After Unassisted Uptake in Myoblasts and Differentiated Myotubes In Vitro A González-Barriga, B Nillessen, J Kranzen, IDG van Kessel, HJE Croes, ... nucleic acid therapeutics 27 (3), 144-158, 2017 | 21 | 2017 |
Integrative cell type-specific multi-omics approaches reveal impaired programs of glial cell differentiation in mouse culture models of DM1 A González-Barriga, L Lallemant, DM Dincã, SO Braz, H Polvèche, ... Frontiers in Cellular Neuroscience 15, 662035, 2021 | 13 | 2021 |
Myotonic dystrophy RNA toxicity alters morphology, adhesion and migration of mouse and human astrocytes DM Dincã, L Lallemant, A González-Barriga, N Cresto, SO Braz, G Sicot, ... Nature Communications 13 (1), 3841, 2022 | 8 | 2022 |
Deciphering the complex molecular pathogenesis of myotonic dystrophy type 1 through omics studies J Espinosa-Espinosa, A González-Barriga, A López-Castel, R Artero International Journal of Molecular Sciences 23 (3), 1441, 2022 | 6 | 2022 |
MBNL‐dependent impaired development within the neuromuscular system in myotonic dystrophy type 1 J Tahraoui‐Bories, A Mérien, A González‐Barriga, J Lainé, C Leteur, ... Neuropathology and Applied Neurobiology 49 (1), e12876, 2023 | 4 | 2023 |
Toxic CUG RNA repeats disrupt developmentally-regulated splicing in oligodendrocytes causing transient hypomyelination in a mouse model of myotonic dystrophy. L Lallemant, S Braz, A González-Barriga, P Magneron, A Cordier, ... The European Meeting on Glial Cells in Health and Disease, 2023 | | 2023 |
Glial cell dysfunction in myotonic dystrophy brain disease D Dinca, S Braz, L Lallemant, A Gonzalez-Barriga, B Potier, S Parrot, ... 12th Japanese-French Workshop: New insights in personalized medicine for …, 2022 | | 2022 |
MBNL-dependent impaired development connectivity within neuromuscular circuits in myotonic dystrophy type 1 J Tahraoui-Bories, A Mérien, F Roussange, A González-Barriga, J Lainé, ... International Myotonic Dystrophy Consortium Meeting, 2022 | | 2022 |
Author Correction: Myotonic dystrophy RNA toxicity alters morphology, adhesion and migration of mouse and human astrocytes DM Dincã, L Lallemant, A González-Barriga, N Cresto, SO Braz, G Sicot, ... Nature Communications 13, 2022 | | 2022 |
Role of miRNAs in muscle atrophy: the myotonic dystrophy paradigm A González-Barriga, R Artero, A López-Castel MicroRNA, 331-362, 2022 | | 2022 |
RNA toxicity in myotonic dystrophy causes pronounced spliceopathy in astrocytes, in association with defective cell adhesion and morphology, erratic migration and impaired … DM Dincã, A González-Barriga, S Braz, LE Pillet, N Cresto, H Polvèche, ... Cold Spring Harbor Laboratory Meeting on Glia in Health and Disease, 2020 | | 2020 |
Real-time monitoring of brain cell models for neuromuscular and neurodegenerative disorders A Gonzalez-Barriga, D Dinca, S Braz, G Gourdon, M Gomes-Pereira Incucyte User Meeting, 2019 | | 2019 |
Toxic RNA affects astrocyte adhesion, spreading and migration in myotonic dystrophy, and impacts neuritogenesis through abnormal glial-neuronal interactions DM Dincã, A González-Barriga, S Braz, CF Bourgeois, G Sicot, C Chhuon, ... The European Meeting on Glial Cells in Health and Disease, 2019 | | 2019 |
Combination of Omics Approaches to Study Molecular Abnormalities in Individual Brain Cell Types of a DM1 Mouse Model A González-Barriga, DM Dincã, S Braz, A Cordier, C Chhuon, IC Guerrera, ... International Myotonic Dystrophy Consortium Meeting, 2019 | | 2019 |
L2 The expanded cag repeat in the huntingtin gene as target for therapeutic RNA modulation throughout the R6/2 and Q175 HD mouse brain A González-Barriga, E Kourkouta, O Kontkanen, T Heikkinen, K Lehtimäki, ... Journal of Neurology, Neurosurgery & Psychiatry 87 (Suppl 1), A90-A91, 2016 | | 2016 |