A 24-week, double-blind, placebo-controlled trial of donepezil in patients with Alzheimer's disease SL Rogers, MR Farlow, RS Doody, R Mohs, LT Friedhoff, ... Neurology 50 (1), 136-145, 1998 | 2167 | 1998 |
The efficacy and safety of donepezil in patients with Alzheimer's disease: results of a US multicentre, randomized, double-blind, placebo-controlled trial SL Rogers, LT Friedhoff Dementia and Geriatric Cognitive Disorders 7 (6), 293-303, 1996 | 1154 | 1996 |
Donepezil improves cognition and global function in Alzheimer disease: a 15-week, double-blind, placebo-controlled study SL Rogers, RS Doody, RC Mohs, LT Friedhoff, Donepezil Study Group Archives of internal medicine 158 (9), 1021-1031, 1998 | 988 | 1998 |
The Effects of Donepezil in Alzheimer’s Disease – Results from a Multinational Trial1 A Burns, M Rossor, J Hecker, S Gauthier, H Petit, HJ Möller, SL Rogers, ... Dementia and geriatric cognitive disorders 10 (3), 237-244, 1999 | 748 | 1999 |
Long-term efficacy and safety of donepezil in the treatment of Alzheimer's disease: an interim analysis of the results of a US multicentre open label extension study SL Rogers, LT Friedhoff European Neuropsychopharmacology 8 (1), 67-75, 1998 | 407 | 1998 |
Cyclin-dependent kinase 8 mediates chemotherapy-induced tumor-promoting paracrine activities DC Porter, E Farmaki, S Altilia, GP Schools, DK West, M Chen, BD Chang, ... Proceedings of the National Academy of Sciences 109 (34), 13799-13804, 2012 | 212 | 2012 |
Pharmacokinetic and pharmacodynamic profile of donepezil HCl following single oral doses Rogers, Friedhoff British journal of clinical pharmacology 46 (S1), 1-6, 1998 | 188 | 1998 |
Treatment with controlled-release lovastatin decreases serum concentrations of human β-amyloid (Aβ) peptide LT Friedhoff, EI Cullen, NSM Geoghagen, JD Buxbaum International Journal of Neuropsychopharmacology 4 (2), 127-130, 2001 | 151 | 2001 |
Metabolism and elimination of 14C‐donepezil in healthy volunteers: a single‐dose study Tiseo, Perdomo, Friedhoff British journal of clinical pharmacology 46 (S1), 19-24, 1998 | 146 | 1998 |
Pharmacological concentrations of the HMG-CoA reductase inhibitor lovastatin decrease the formation of the Alzheimer beta-amyloid peptide in vitro and in patients JD Buxbaum, EI Cullen, LT Friedhoff Front Biosci 7, a50-a59, 2002 | 135 | 2002 |
Pharmacokinetic and pharmacodynamic profile of donepezil HCl following multiple oral doses Rogers, Sukovaty, Pederson, Lee, Friedhoff British Journal of Clinical Pharmacology 46 (S1), 7-12, 1998 | 116 | 1998 |
Pharmacokinetic and pharmacodynamic profile of donepezil HCl following evening administration Tiseo, Rogers, Friedhoff British journal of clinical pharmacology 46 (S1), 13-18, 1998 | 114 | 1998 |
A lipid A analog, E5531, blocks the endotoxin response in human volunteers with experimental endotoxemia E Bunnell, M Lynn, K Habet, A Neumann, CA Perdomo, LT Friedhoff, ... Critical care medicine 28 (8), 2713-2720, 2000 | 111 | 2000 |
the Donepezil Study Group: The efficacy and safety of donepezil in patients with Alzheimer's disease: results of a US multicentre, randomized, double-blind, placebo-controlled … SL Rogers, LT Friedhoff Dementia 7 (6), 293-303, 1996 | 96 | 1996 |
Cholesterol depletion with physiological concentrations of a statin decreases the formation of the Alzheimer amyloid Aβ peptide JD Buxbaum, NSM Geoghagen, LT Friedhoff Journal of Alzheimer's Disease 3 (2), 221-229, 2001 | 92 | 2001 |
Concurrent administration of donepezil HCl and ketoconazole: assessment of pharmacokinetic changes following single and multiple doses PJ Tiseo, CA Perdomo, LT Friedhoff British journal of clinical pharmacology 46 (Suppl 1), 30, 1998 | 88 | 1998 |
Phenserine efficacy in Alzheimer's disease B Winblad, E Giacobini, L Frölich, LT Friedhoff, G Bruinsma, RE Becker, ... Journal of Alzheimer's Disease 22 (4), 1201-1208, 2010 | 87 | 2010 |
Method of treating amyloid beta precursor disorders L Friedhoff, J Buxbaum, E Cullen US Patent App. 10/067,593, 2002 | 66 | 2002 |
Concurrent administration of donepezil HCl and cimetidine: assessment of pharmacokinetic changes following single and multiple doses Tiseo, Perdomo, Friedhoff British journal of clinical pharmacology 46 (S1), 25-29, 1998 | 66 | 1998 |
Ascending‐dose study of noribogaine in healthy volunteers: Pharmacokinetics, pharmacodynamics, safety, and tolerability P Glue, M Lockhart, F Lam, N Hung, CT Hung, L Friedhoff The Journal of Clinical Pharmacology 55 (2), 189-194, 2015 | 62 | 2015 |