Anti-inflammatory small molecules to treat seizures and epilepsy: from bench to bedside A Dey, X Kang, J Qiu, Y Du, J Jiang Trends in pharmacological sciences 37 (6), 463-484, 2016 | 204 | 2016 |
Age-associated oxidative damage to the p62 promoter: implications for Alzheimer disease Y Du, MC Wooten, M Gearing, MW Wooten Free Radical Biology and Medicine 46 (4), 492-501, 2009 | 119 | 2009 |
Subarachnoid blood acutely induces spreading depolarizations and early cortical infarction JA Hartings, J York, CP Carroll, JM Hinzman, E Mahoney, B Krueger, ... Brain 140 (10), 2673-2690, 2017 | 109 | 2017 |
Oxidative damage to the promoter region of SQSTM1/p62 is common to neurodegenerative disease Y Du, MC Wooten, MW Wooten Neurobiology of disease 35 (2), 302-310, 2009 | 108 | 2009 |
A role for sequestosome 1/p62 in mitochondrial dynamics, import and genome integrity ML Seibenhener, Y Du, MT Diaz-Meco, J Moscat, MC Wooten, ... Biochimica Et Biophysica Acta (BBA)-Molecular Cell Research 1833 (3), 452-459, 2013 | 88 | 2013 |
Neuroprotective effects of INT-777 against Aβ1–42-induced cognitive impairment, neuroinflammation, apoptosis, and synaptic dysfunction in mice X Wu, YG Lv, YF Du, F Chen, MN Reed, M Hu, V Suppiramaniam, ... Brain, Behavior, and Immunity 73, 533-545, 2018 | 71 | 2018 |
Inhibitory effect of INT-777 on lipopolysaccharide-induced cognitive impairment, neuroinflammation, apoptosis, and synaptic dysfunction in mice X Wu, YG Lv, YF Du, M Hu, MN Reed, Y Long, V Suppiramaniam, H Hong, ... Progress in Neuro-Psychopharmacology and Biological Psychiatry 88, 360-374, 2019 | 60 | 2019 |
Targeted inhibition of RAGE reduces amyloid-β influx across the blood-brain barrier and improves cognitive deficits in db/db mice H Wang, F Chen, YF Du, Y Long, MN Reed, M Hu, V Suppiramaniam, ... Neuropharmacology 131, 143-153, 2018 | 58 | 2018 |
Cyclooxygenase-2 contributes to oxidopamine-mediated neuronal inflammation and injury via the prostaglandin E2 receptor EP2 subtype X Kang, J Qiu, Q Li, KA Bell, Y Du, DW Jung, JY Lee, J Hao, J Jiang Scientific reports 7 (1), 9459, 2017 | 53 | 2017 |
Small‐molecule inhibition of prostaglandin E receptor 2 impairs cyclooxygenase‐associated malignant glioma growth J Qiu, Q Li, KA Bell, X Yao, Y Du, E Zhang, JJ Yu, Y Yu, Z Shi, J Jiang British journal of pharmacology 176 (11), 1680-1699, 2019 | 52 | 2019 |
Suppressing pro-inflammatory prostaglandin signaling attenuates excitotoxicity-associated neuronal inflammation and injury J Jiang, Y Yu, ER Kinjo, Y Du, HP Nguyen, R Dingledine Neuropharmacology 149, 149-160, 2019 | 45 | 2019 |
Defining the therapeutic time window for suppressing the inflammatory prostaglandin E2 signaling after status epilepticus Y Du, T Kemper, J Qiu, J Jiang Expert review of neurotherapeutics 16 (2), 123-130, 2016 | 40 | 2016 |
aPKC phosphorylation of HDAC6 results in increased deacetylation activity Y Du, ML Seibenhener, J Yan, J Jiang, MC Wooten PloS one 10 (4), e0123191, 2015 | 34 | 2015 |
Interaction of SQSTM1 with the motor protein dynein–SQSTM1 is required for normal dynein function and trafficking L Calderilla-Barbosa, ML Seibenhener, Y Du, MT Diaz-Meco, J Moscat, ... Journal of Cell Science 127 (18), 4052-4063, 2014 | 33 | 2014 |
Protective effects of tauroursodeoxycholic acid on lipopolysaccharide-induced cognitive impairment and neurotoxicity in mice X Wu, C Liu, L Chen, YF Du, M Hu, MN Reed, Y Long, V Suppiramaniam, ... International Immunopharmacology 72, 166-175, 2019 | 30 | 2019 |
Antidepressant-like effect of zileuton is accompanied by hippocampal neuroinflammation reduction and CREB/BDNF upregulation in lipopolysaccharide-challenged mice DD Li, H Xie, YF Du, Y Long, MN Reed, M Hu, V Suppiramaniam, H Hong, ... J Affect Disord 227, 672-680, 2018 | 28 | 2018 |
Behavioral effects of SQSTM1/p62 overexpression in mice: support for a mitochondrial role in depression and anxiety ML Seibenhener, T Zhao, Y Du, L Calderilla-Barbosa, J Yan, J Jiang, ... Behavioural brain research 248, 94-103, 2013 | 23 | 2013 |
Hippocampal genetic knockdown of PPARδ causes depression-like behaviors and neurogenesis suppression F Chen, X Yu, G Meng, Z Mei, Y Du, H Sun, MN Reed, L Kong, ... International Journal of Neuropsychopharmacology 22 (6), 372-382, 2019 | 18 | 2019 |
Neuronal CXCL10/CXCR3 axis mediates the induction of cerebral hyperexcitability by peripheral viral challenge TJ Petrisko, J Bloemer, PD Pinky, S Srinivas, RT Heslin, Y Du, SE Setti, ... Frontiers in Neuroscience 14, 220, 2020 | 15 | 2020 |
CRISPR/Cas9-mediated CysLT1R deletion reverses synaptic failure, amyloidosis and cognitive impairment in APP/PS1 mice F Chen, S Fang, Y Du, A Ghosh, MN Reed, Y Long, V Suppiramaniam, ... Aging (albany NY) 13 (5), 6634, 2021 | 13 | 2021 |