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Nigam M. Mishra
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Evaluation of the antibacterial and antibiofilm activities of novel CRAMP–vancomycin conjugates with diverse linkers
NM Mishra, Y Briers, C Lamberigts, H Steenackers, S Robijns, B Landuyt, ...
Organic & Biomolecular Chemistry 13 (27), 7477-7486, 2015
532015
Copper‐Catalyzed Diversity‐Oriented Three‐and Five‐Component Synthesis of Mono‐and Dipropargylic Amines via Coupling of Alkynes, α‐Amino Esters and Aldehydes
N Sharma, UK Sharma, NM Mishra, EV Van der Eycken
Advanced Synthesis & Catalysis 356 (5), 1029-1037, 2014
332014
VU0606170, a selective slack channels inhibitor, decreases calcium oscillations in cultured cortical neurons
BD Spitznagel, NM Mishra, AM Qunies, FJ Prael III, Y Du, KA Kozek, ...
ACS Chemical Neuroscience 11 (21), 3658-3671, 2020
212020
Stress and interferon signalling-mediated apoptosis contributes to pleiotropic anticancer responses induced by targeting NGLY1
A Zolekar, VJT Lin, NM Mishra, YY Ho, HS Hayatshahi, A Parab, ...
British Journal of Cancer 119 (12), 1538-1551, 2018
192018
Helicobacter pylori antigenic Lpp20 is a structural homologue of Tipα and promotes epithelial-mesenchymal transition
GZ Francesca Vallese, Nigam M. Mishra, Matteo Pagliari, Paola Berto, Gaia ...
Biochimica et Biophysica Acta (BBA) - General Subjects, 2017
192017
Highly Selective Y4 Receptor Antagonist Binds in an Allosteric Binding Pocket
C Schüß, O Vu, M Schubert, Y Du, NM Mishra, IR Tough, J Stichel, ...
Journal of Medicinal Chemistry 64 (5), 2801-2814, 2021
142021
Iterative Chemical Engineering of Vancomycin Leads to Novel Vancomycin Analogs With a High in Vitro Therapeutic Index
NM Mishra, I Stolarzewicz, D Cannaerts, J Schuermans, R Lavigne, ...
Frontiers in Microbiology 9, 1175, 2018
132018
Diversely Substituted Imidazo[1,2‐a]pyrazine‐8‐oxo‐3‐carbaldehydes: An Iodine‐Mediated Cyclization/Oxidation Approach
NM Mishra, DD Vachhani, SG Modha, EV Van der Eycken
European Journal of Organic Chemistry 2013 (4), 693-700, 2013
102013
Alkylation of 3, 5-dichloro-2 (1H)-pyrazinones using malonate esters
NM Mishra, VA Peshkov, OP Pereshivko, SG Modha, EV Van der Eycken
Tetrahedron Letters 53 (35), 4676-4678, 2012
62012
Structure–activity relationship studies in a new series of 2-amino-N-phenylacetamide inhibitors of Slack potassium channels
MQ Alshaima'a, NM Mishra, BD Spitznagel, Y Du, VS Acuña, CD Weaver, ...
Bioorganic & medicinal chemistry letters 76, 129013, 2022
42022
Structure–Activity Relationship Study of the High-Affinity Neuropeptide Y4 Receptor Positive Allosteric Modulator VU0506013
C Schüß, O Vu, NM Mishra, IR Tough, Y Du, J Stichel, HM Cox, ...
Journal of Medicinal Chemistry 66 (13), 8745-8766, 2023
22023
Targeting protein deglycosylation as a newly identified vulnerable point in melanoma
VJT Lin, A Zolekar, NM Mishra, YY Ho, HS Hayatshahi, A Parab, ...
Cancer Research 79 (13_Supplement), 3048-3048, 2019
12019
Inhibition of ngly1 for the treatment of cancer
YC Wang, VJT Lin, AA Zolekar, KA Emmitte, NM Mishra, J Liu
US Patent App. 18/454,671, 2024
2024
Inhibition of NGLY1 for the treatment of cancer
YC Wang, VJT Lin, A Zolekar, KA Emmitte, NM Mishra, J Liu
US Patent 11,779,592, 2023
2023
Structural optimization of VU0609159 as an activator of Slack potassium channels
P Peprah, Y Du, B Spitznagel, N Mishra, A Qunies, D Weaver, K Emmitte
2023
Optimization of benzo [d] oxazol-2 (3H)-one activators of Slack potassium channels
N Mishra, Y Du, B Spitznagel, C Weaver, K Emmitte
2022
Discovery of Small Molecule Slack Inhibitors for the Treatment of MMPSI: SAR Development in the Western and Central Region of Hit Compound VU0606170
N Mishra, A Qunies, B Spitznagel, V Acuna, J Acebo, C Weaver, ...
2021
Discovery of Small Molecule Slack Inhibitors for the Treatment of MMPSI: SAR Development in the Eastern Region of Hit Compound VU0606170
A Qunies, N Mishra, E Tran, B Spitznagel, C Weaver, K Emmitte
2021
Identification of NGLY1-mediated protein deglycosylation as a vulnerable point in melanoma.
V Lin, A Zolekar, N Mishra, YY Ho, H Hayatshahi, A Parab, R Sampat, ...
CANCER RESEARCH 80 (19), 44-44, 2020
2020
Abstract A28: Identification of NGLY1-mediated protein deglycosylation as a vulnerable point in melanoma
V Lin, A Zolekar, N Mishra, YY Ho, H Hayatshahi, A Parab, R Sampat, ...
Cancer Research 80 (19_Supplement), A28-A28, 2020
2020
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