| Guidelines for the use and interpretation of assays for monitoring autophagy (4th edition)1 DJ Klionsky, AK Abdel-Aziz, S Abdelfatah, M Abdellatif, A Abdoli, S Abel, ... autophagy 17 (1), 1-382, 2021 | 13173* | 2021 |
| Gain of function of a p53 hot spot mutation in a mouse model of Li-Fraumeni syndrome GA Lang, T Iwakuma, YA Suh, G Liu, VA Rao, JM Parant, ... Cell 119 (6), 861-872, 2004 | 1205 | 2004 |
| Repair of and checkpoint response to topoisomerase I-mediated DNA damage Y Pommier, C Redon, VA Rao, JA Seiler, O Sordet, H Takemura, S Antony, ... Mutation Research/Fundamental and Molecular Mechanisms of Mutagenesis 532 (1 …, 2003 | 390 | 2003 |
| Repair of topoisomerase I‐mediated DNA damage Y Pommier, JM Barcelo, VA Rao, O Sordet, AG Jobson, L Thibaut, ... Progress in nucleic acid research and molecular biology 81, 179-229, 2006 | 353 | 2006 |
| Immune-mediated pathology in Duchenne muscular dystrophy AS Rosenberg, M Puig, K Nagaraju, EP Hoffman, SA Villalta, VA Rao, ... Science translational medicine 7 (299), 299rv4-299rv4, 2015 | 270 | 2015 |
| Mechanisms of apoptosis induction by nucleoside analogs D Sampath, VA Rao, W Plunkett Oncogene 22 (56), 9063-9074, 2003 | 270 | 2003 |
| The complexity of phosphorylated H2AX foci formation and DNA repair assembly at DNA double-strand breaks AJ Nakamura, VA Rao, Y Pommier, WM Bonner Cell cycle 9 (2), 389-397, 2010 | 183 | 2010 |
| The iron chelator Dp44mT causes DNA damage and selective inhibition of topoisomerase IIα in breast cancer cells VA Rao, SR Klein, KK Agama, E Toyoda, N Adachi, Y Pommier, ... Cancer research 69 (3), 948-957, 2009 | 168 | 2009 |
| The antioxidant transcription factor Nrf2 negatively regulates autophagy and growth arrest induced by the anticancer redox agent mitoquinone VA Rao, SR Klein, SJ Bonar, J Zielonka, N Mizuno, JS Dickey, PW Keller, ... Journal of Biological Chemistry 285 (45), 34447-34459, 2010 | 152 | 2010 |
| Mitochondrial topoisomerase I (top1mt) is a novel limiting factor of doxorubicin cardiotoxicity S Khiati, I Dalla Rosa, C Sourbier, X Ma, VA Rao, LM Neckers, H Zhang, ... Clinical Cancer Research 20 (18), 4873-4881, 2014 | 132 | 2014 |
| Defective Mre11-dependent activation of Chk2 by ataxia telangiectasia mutated in colorectal carcinoma cells in response to replication-dependent DNA double strand breaks H Takemura, VA Rao, O Sordet, T Furuta, ZH Miao, LH Meng, H Zhang, ... Journal of Biological Chemistry 281 (41), 30814-30823, 2006 | 127 | 2006 |
| Phosphorylation of BLM, dissociation from topoisomerase IIIα, and colocalization with γ-H2AX after topoisomerase I-induced replication damage VA Rao, AM Fan, LH Meng, CF Doe, PS North, ID Hickson, Y Pommier Molecular and cellular biology 25 (20), 8925-8937, 2005 | 111 | 2005 |
| Targeting chk2 kinase: molecular interaction maps and therapeutic rationale Y Pommier, O Sordet, A Rao, H Zhang, KW Kohn Current pharmaceutical design 11 (22), 2855, 2005 | 111 | 2005 |
| Chk2 molecular interaction map and rationale for Chk2 inhibitors Y Pommier, JN Weinstein, MI Aladjem, KW Kohn Clinical cancer research 12 (9), 2657-2661, 2006 | 105 | 2006 |
| Endogenous γ-H2AX-ATM-Chk2 Checkpoint Activation in Bloom's Syndrome Helicase–Deficient Cells Is Related to DNA Replication Arrested Forks VA Rao, C Conti, J Guirouilh-Barbat, A Nakamura, ZH Miao, SL Davies, ... Molecular cancer research 5 (7), 713-724, 2007 | 103 | 2007 |
| Batracylin (NSC 320846), a dual inhibitor of DNA topoisomerases I and II induces histone γ-H2AX as a biomarker of DNA damage VA Rao, K Agama, S Holbeck, Y Pommier Cancer research 67 (20), 9971-9979, 2007 | 87 | 2007 |
| Doxorubicin-induced carbonylation and degradation of cardiac myosin binding protein C promote cardiotoxicity B Aryal, J Jeong, VA Rao Proceedings of the National Academy of Sciences 111 (5), 2011-2016, 2014 | 82 | 2014 |
| Bloom's syndrome helicase and Mus81 are required to induce transient double-strand DNA breaks in response to DNA replication stress T Shimura, MJ Torres, MM Martin, VA Rao, Y Pommier, M Katsura, ... Journal of molecular biology 375 (4), 1152-1164, 2008 | 81 | 2008 |
| Mito-tempol and dexrazoxane exhibit cardioprotective and chemotherapeutic effects through specific protein oxidation and autophagy in a syngeneic breast tumor preclinical model JS Dickey, Y Gonzalez, B Aryal, S Mog, AJ Nakamura, CE Redon, U Baxa, ... PloS one 8 (8), e70575, 2013 | 72 | 2013 |
| Therapeutic targeting of the mitochondria initiates excessive superoxide production and mitochondrial depolarization causing decreased mtDNA integrity KL Pokrzywinski, TG Biel, D Kryndushkin, VA Rao PLoS One 11 (12), e0168283, 2016 | 70 | 2016 |
Yves PommierChief, Developmental Therapeutics Branch & Laboratory of Molecular PharmacologyVerified email at nih.gov
