| Structural insights into TDP-43 and effects of post-translational modifications L François-Moutal, S Perez-Miller, DD Scott, VG Miranda, N Mollasalehi, ... Frontiers in molecular neuroscience 12, 301, 2019 | 104 | 2019 |
| Small Molecule Targeting TDP-43’s RNA Recognition Motifs Reduces Locomotor Defects in a Drosophila Model of Amyotrophic Lateral Sclerosis (ALS) L François-Moutal, R Felemban, DD Scott, MR Sayegh, VG Miranda, ... ACS chemical biology 14 (9), 2006-2013, 2019 | 48 | 2019 |
| The natural flavonoid naringenin elicits analgesia through inhibition of NaV1. 8 voltage-gated sodium channels Y Zhou, S Cai, A Moutal, J Yu, K Gómez, CL Madura, Z Shan, NYN Pham, ... ACS Chemical Neuroscience 10 (12), 4834-4846, 2019 | 23 | 2019 |
| Selective targeting of NaV1. 7 via inhibition of the CRMP2-Ubc9 interaction reduces pain in rodents S Cai, A Moutal, J Yu, LA Chew, J Isensee, R Chawla, K Gomez, S Luo, ... Science Translational Medicine 13 (619), eabh1314, 2021 | 22 | 2021 |
| An allosteric modulator of RNA binding targeting the N-terminal domain of TDP-43 yields neuroprotective properties N Mollasalehi, L Francois-Moutal, DD Scott, JA Tello, H Williams, ... ACS chemical biology 15 (11), 2854-2859, 2020 | 21 | 2020 |
| Chemical shift perturbation mapping of the Ubc9-CRMP2 interface identifies a pocket in CRMP2 amenable for allosteric modulation of Nav1. 7 channels L François-Moutal, DD Scott, S Perez-Miller, V Gokhale, M Khanna, ... Channels 12 (1), 219-227, 2018 | 16 | 2018 |
| Heat shock protein Grp78/BiP/HspA5 binds directly to TDP-43 and mitigates toxicity associated with disease pathology L François-Moutal, DD Scott, AJ Ambrose, CJ Zerio, ... Scientific reports 12 (1), 8140, 2022 | 11 | 2022 |
| A chemical biology approach to model pontocerebellar hypoplasia type 1B (PCH1B) L François-Moutal, S Jahanbakhsh, ADL Nelson, D Ray, DD Scott, ... ACS chemical biology 13 (10), 3000-3010, 2018 | 11 | 2018 |
| Direct targeting of TDP-43, from small molecules to biologics: the therapeutic landscape L Francois-Moutal, DD Scott, M Khanna RSC Chemical Biology 2 (4), 1158-1166, 2021 | 10 | 2021 |
| 1H, 15N and 13C backbone assignment of apo TDP-43 RNA recognition motifs DD Scott, L Francois-Moutal, VK Kumirov, M Khanna Biomolecular NMR assignments 13, 163-167, 2019 | 6 | 2019 |
| Corrigendum: Structural Insights Into TDP-43 and Effects of Post-translational Modifications L François-Moutal, S Perez-Miller, DD Scott, VG Miranda, N Mollasalehi, ... Frontiers in molecular neuroscience 13, 45-45, 2020 | 2 | 2020 |
| Molecular Dynamics simulation of TDP-43 RRM in the presence and absence of RNA DD Scott, D Mowrey, K Nagarajan, L François-Moutal, A Nair, M Khanna bioRxiv, 2022.03. 15.484514, 2022 | 1 | 2022 |
| Small molecule inhibitors of tdp-43 activity and uses thereof M Khanna, V Gokhale, L Francois-Moutal, D Scott, H Williams, J Tello, ... US Patent App. 18/015,775, 2023 | | 2023 |
| Structure-Based Targeting of Tdp-43 to Further the Development of Novel Therapeutics for Neurodegenerative Diseases DD Scott The University of Arizona, 2022 | | 2022 |
| Heat Shock Protein Grp78/BiP/HspA5 Binds Directly to TDP-43 and Mitigates Toxicity Associated with Neurodegenerative Disease Pathology L François-Moutal, D Scott, A Ambrose, C Zerio, K Dissanayake, D May, ... | | 2021 |
| Structural Insights Into TDP-43 and Effects of Post-translational Modifications (vol 12, 301, 2019) L Francois-Moutal, S Perez-Miller, DD Scott, VG Miranda, N Mollasalehi, ... FRONTIERS IN MOLECULAR NEUROSCIENCE 13, 2020 | | 2020 |
