| SARS-CoV-2 productively infects human gut enterocytes MM Lamers, J Beumer, J van der Vaart, K Knoops, J Puschhof, ... Science 369 (6499), 50-54, 2020 | 1708 | 2020 |
| Mutational signature in colorectal cancer caused by genotoxic pks+E. coli C Pleguezuelos-Manzano, J Puschhof, A Rosendahl Huber, A van Hoeck, ... Nature 580 (7802), 269-273, 2020 | 699 | 2020 |
| Targeting wild-type KRAS-amplified gastroesophageal cancer through combined MEK and SHP2 inhibition GS Wong, J Zhou, JB Liu, Z Wu, X Xu, T Li, D Xu, SE Schumacher, ... Nature medicine 24 (7), 968-977, 2018 | 232 | 2018 |
| High-resolution mRNA and secretome atlas of human enteroendocrine cells J Beumer, J Puschhof, J Bauzá-Martinez, A Martínez-Silgado, ... Cell 181 (6), 1291-1306. e19, 2020 | 137 | 2020 |
| Intestinal organoid cocultures with microbes J Puschhof, C Pleguezuelos-Manzano, A Martinez-Silgado, N Akkerman, ... Nature protocols 16 (10), 4633-4649, 2021 | 125 | 2021 |
| Establishment and culture of human intestinal organoids derived from adult stem cells C Pleguezuelos‐Manzano, J Puschhof, S van den Brink, V Geurts, ... Current protocols in immunology 130 (1), e106, 2020 | 107 | 2020 |
| Snake venom gland organoids Y Post, J Puschhof, J Beumer, HM Kerkkamp, MAG de Bakker, ... Cell 180 (2), 233-247. e21, 2020 | 101 | 2020 |
| Organoids and organs-on-chips: Insights into human gut-microbe interactions J Puschhof, C Pleguezuelos-Manzano, H Clevers Cell host & microbe 29 (6), 867-878, 2021 | 99 | 2021 |
| Next-generation surrogate Wnts support organoid growth and deconvolute frizzled pleiotropy in vivo Y Miao, A Ha, W de Lau, K Yuki, AJM Santos, C You, MH Geurts, ... Cell Stem Cell 27 (5), 840-851. e6, 2020 | 92 | 2020 |
| A CRISPR/Cas9 genetically engineered organoid biobank reveals essential host factors for coronaviruses J Beumer, MH Geurts, MM Lamers, J Puschhof, J Zhang, J van der Vaart, ... Nature communications 12 (1), 5498, 2021 | 66 | 2021 |
| Uncovering the mode of action of engineered T cells in patient cancer organoids JF Dekkers, M Alieva, A Cleven, F Keramati, AKL Wezenaar, EJ van Vliet, ... Nature biotechnology 41 (1), 60-69, 2023 | 64 | 2023 |
| Long-term expansion and differentiation of adult murine epidermal stem cells in 3D organoid cultures KE Boonekamp, K Kretzschmar, DJ Wiener, P Asra, S Derakhshan, ... Proceedings of the National Academy of Sciences 116 (29), 14630-14638, 2019 | 64 | 2019 |
| BMP gradient along the intestinal villus axis controls zonated enterocyte and goblet cell states J Beumer, J Puschhof, FY Yengej, L Zhao, A Martinez-Silgado, ... Cell Reports 38 (9), 2022 | 53 | 2022 |
| Novel chimeric gene therapy vectors based on adeno-associated virus and four different mammalian bocaviruses J Fakhiri, MA Schneider, J Puschhof, M Stanifer, V Schildgen, ... Molecular Therapy-Methods & Clinical Development 12, 202-222, 2019 | 47 | 2019 |
| A turquoise fluorescence lifetime-based biosensor for quantitative imaging of intracellular calcium FH van der Linden, EK Mahlandt, JJG Arts, J Beumer, J Puschhof, ... Nature communications 12 (1), 7159, 2021 | 43 | 2021 |
| 5-aza-2′-deoxycytidine (DAC) treatment downregulates the HPV E6 and E7 oncogene expression and blocks neoplastic growth of HPV-associated cancer cells M Stich, L Ganss, J Puschhof, ES Prigge, M Reuschenbach, A Guiterrez, ... Oncotarget 8 (32), 52104, 2017 | 36 | 2017 |
| Colon tumors in enterotoxigenic Bacteroides fragilis (ETBF)-colonized mice do not display a unique mutational signature but instead possess host-dependent alterations in the … J Allen, A Rosendahl Huber, C Pleguezuelos-Manzano, J Puschhof, S Wu, ... Microbiology spectrum 10 (3), e01055-22, 2022 | 22 | 2022 |
| Derivation of snake venom gland organoids for in vitro venom production J Puschhof, Y Post, J Beumer, HM Kerkkamp, M Bittenbinder, FJ Vonk, ... Nature Protocols 16 (3), 1494-1510, 2021 | 15 | 2021 |
| Human microbiome research: Growing pains and future promises J Puschhof, E Elinav PLoS biology 21 (3), e3002053, 2023 | 14 | 2023 |
| Rapid tissue prototyping with micro-organospheres Z Wang, M Boretto, R Millen, N Natesh, ES Reckzeh, C Hsu, M Negrete, ... Stem cell reports 17 (9), 1959-1975, 2022 | 14 | 2022 |
Hans CleversHubrecht Institute - UtrechtVerified email at hubrecht.eu
