Motor neuron disease, TDP-43 pathology, and memory deficits in mice expressing ALS–FTD-linked UBQLN2 mutations NTT Le, L Chang, I Kovlyagina, P Georgiou, N Safren, KE Braunstein, ... Proceedings of the National Academy of Sciences 113 (47), E7580-E7589, 2016 | 93 | 2016 |
Defined α-synuclein prion-like molecular assemblies spreading in cell culture S Aulić, TTN Le, F Moda, S Abounit, S Corvaglia, L Casalis, S Gustincich, ... BMC neuroscience 15, 1-12, 2014 | 87 | 2014 |
ALS/FTD mutations in UBQLN2 impede autophagy by reducing autophagosome acidification through loss of function JJ Wu, A Cai, JE Greenslade, NR Higgins, C Fan, NTT Le, M Tatman, ... Proceedings of the National Academy of Sciences 117 (26), 15230-15241, 2020 | 66 | 2020 |
Prions activate a p38 MAPK synaptotoxic signaling pathway C Fang, B Wu, NTT Le, T Imberdis, RCC Mercer, DA Harris PLoS pathogens 14 (9), e1007283, 2018 | 62 | 2018 |
Prion neurotoxicity NTT Le, B Wu, DA Harris Brain Pathology 29 (2), 263-277, 2019 | 27 | 2019 |
Synthetic prions with novel strain-specified properties F Moda, TN T. Le, S Aulić, E Bistaffa, I Campagnani, T Virgilio, A Indaco, ... PLoS pathogens 11 (12), e1005354, 2015 | 27 | 2015 |
Synthetic prions and other human neurodegenerative proteinopathies NTT Le, J Narkiewicz, S Aulić, G Salzano, HT Tran, D Scaini, F Moda, ... Virus research 207, 25-37, 2015 | 21 | 2015 |
Synthetic prions G Legname, TNL Tran, G Giachin Prions and Prion Diseases: New Developments, 61-83, 2012 | 5 | 2012 |
P4‐506: ROLE OF P38α MAP KINASE IN AMYLOID‐β DERIVED DIFFUSIBLE LIGAND (ADDL) INDUCED DENDRITIC SPINE LOSS IN HIPPOCAMPAL NEURONS L Amin, N Le, RCC Mercer, U Germann, J Alam, DA Harris Alzheimer's & Dementia 15, P1507-P1507, 2019 | 2 | 2019 |
Nanobody-stabilize the crystal structure of full-length human PrP R Abskharon, S Soror, G Giachin, E Pardon, H El Hassan, G Legname, ... Prion 6 (S), 115-115, 2012 | 2 | 2012 |
Improved statistical benchmarking of digital pathology models using pairwise frames evaluation Y Gerardin, J Shamshoian, J Shen, N Le, J Prezioso, J Abel, I Finberg, ... arXiv preprint arXiv:2306.04709, 2023 | 1 | 2023 |
ML quantification of tumor-Infiltrating lymphocytes distinguishes immune-phenotypes and reveals phenotypic heterogeneity N Le, B Rahsepar, J Hipp, J Conway, Y Gerardin, E Krause, C Shen, ... Cancer Research 84 (6_Supplement), 905-905, 2024 | | 2024 |
110 Deep learning models identify key tumor microenvironment features associated with genetic signatures of UV mutagenesis and alkylating agent treatment in melanoma S Nofallah, DT Sanghavi, S Gupta, C Shen, N Le, L Yu, B Rahsepar, ... Journal for ImmunoTherapy of Cancer 11 (Suppl 1), 2023 | | 2023 |
122 Quantification of tumor infiltrating lymphocytes (TILs) from pathology slides reflects molecular immune phenotypes C Shen, S Nofallah, J Conway, C Parmar, MG Drage, F Najdawi, ... Journal for ImmunoTherapy of Cancer 11 (Suppl 1), 2023 | | 2023 |
NMDA receptor misalignment in iPSC-derived neurons from a multi-generational family with inherited Creutzfeldt-Jakob disease NTT Le, RCC Mercer, AD Gojanovich, A Anane, S Park, B Wu, PS Bawa, ... bioRxiv, 2022.05. 20.491674, 2022 | | 2022 |
Signalling pathways underlying prion neurotoxicity NT Le, RC Mercer, DA Harris PRION 13, 17-17, 2019 | | 2019 |
'Novel compounds for the treatment of prion disease' RCC Mercer, NTT Le, D Fraser, A Beeler, DA Harris PRION 13, 128-128, 2019 | | 2019 |
Distinct disease phenotypes produced by a de novo generated synthetic prion strain: Conformational instability before adaptation F Moda, NTT Le, T Virgilio, S Mazzetti, S Aulic, L Palamara, I Campagnani, ... Prion 2015 Poster Abstracts.(9 (suppl. 1)) 2015; Prion 2015, Fort Collins …, 2015 | | 2015 |
Synthetic Infectious Prions G Legname, NLT Thanh 4th International Conference on Biomedical Engineering in Vietnam, 380-383, 2013 | | 2013 |
Synthetic human alpha-synuclein prions L Ntt, T Hna, S Aulic, F Moda, P Zucca, F Tagliavini, S Gustincich, ... PRION 7, 14-14, 2013 | | 2013 |