The metabolic effects of GDF15 are mediated by the orphan receptor GFRAL PJ Emmerson, F Wang, Y Du, Q Liu, RT Pickard, MD Gonciarz, T Coskun, ... Nature medicine 23 (10), 1215-1219, 2017 | 499 | 2017 |
High-throughput screening and selection of yeast cell lines expressing monoclonal antibodies GC Barnard, AR Kull, NS Sharkey, SS Shaikh, AM Rittenhour, I Burnina, ... Journal of Industrial Microbiology and Biotechnology 37 (9), 961-971, 2010 | 88 | 2010 |
Integrated Recombinant Protein Expression and Purification Platform Based on Ralstonia eutropha GC Barnard, JD McCool, DW Wood, TU Gerngross Applied and environmental microbiology 71 (10), 5735-5742, 2005 | 84 | 2005 |
High level recombinant protein expression in Ralstonia eutropha using T7 RNA polymerase based amplification GC Barnard, GE Henderson, S Srinivasan, TU Gerngross Protein expression and purification 38 (2), 264-271, 2004 | 76 | 2004 |
A high cell density transient transfection system for therapeutic protein expression based on a CHO GS‐knockout cell line: process development and product quality assessment Y Rajendra, MD Hougland, R Alam, TA Morehead, GC Barnard Biotechnology and bioengineering 112 (5), 977-986, 2015 | 66 | 2015 |
A Novel High-Cell-Density Protein Expression System Based on Ralstonia eutropha S Srinivasan, GC Barnard, TU Gerngross Applied and Environmental Microbiology 68 (12), 5925-5932, 2002 | 57 | 2002 |
Optimization of erythropoietin production with controlled glycosylation-PEGylated erythropoietin produced in glycoengineered Pichia pastoris JH Nett, S Gomathinayagam, SR Hamilton, B Gong, RC Davidson, M Du, ... Journal of biotechnology 157 (1), 198-206, 2012 | 47 | 2012 |
Production of recombinant proteins using multiple‐copy gene integration in high‐cell‐density fermentations of Ralstonia eutropha S Srinivasan, GC Barnard, TU Gerngross Biotechnology and bioengineering 84 (1), 114-120, 2003 | 42 | 2003 |
Generation of stable Chinese hamster ovary pools yielding antibody titers of up to 7.6 g/L using the piggyBac transposon system Y Rajendra, RB Peery, GC Barnard Biotechnology progress 32 (5), 1301-1307, 2016 | 34 | 2016 |
High‐throughput mAb expression and purification platform based on transient CHO GC Barnard, MD Hougland, Y Rajendra Biotechnology progress 31 (1), 239-247, 2015 | 31 | 2015 |
Evaluation of piggyBac‐mediated CHO pools to enable material generation to support GLP toxicology studies Y Rajendra, S Balasubramanian, NA McCracken, DL Norris, Z Lian, ... Biotechnology Progress 33 (6), 1436-1448, 2017 | 26 | 2017 |
Generation of high expressing Chinese hamster ovary cell pools using the Leap‐In transposon system S Balasubramanian, RB Peery, J Minshull, M Lee, R White, RM Kelly, ... Biotechnology Journal 13 (10), 1700748, 2018 | 25 | 2018 |
Bioreactor scale up and protein product quality characterization of piggyBac transposon derived CHO pools Y Rajendra, S Balasubramanian, RB Peery, JR Swartling, NA McCracken, ... Biotechnology Progress 33 (2), 534-540, 2017 | 24 | 2017 |
Transient and stable CHO expression, purification and characterization of novel hetero‐dimeric bispecific I g G antibodies Y Rajendra, RB Peery, MD Hougland, GC Barnard, X Wu, JR Fitchett, ... Biotechnology Progress 33 (2), 469-477, 2017 | 21 | 2017 |
Transcriptional and post-transcriptional targeting for enhanced transient gene expression in CHO cells Y Rajendra, MD Hougland, MG Schmitt, GC Barnard Biotechnology letters 37, 2379-2386, 2015 | 18 | 2015 |
Production and purification of self-assembling peptides in Ralstonia eutropha DC Reed, GC Barnard, EB Anderson, LT Klein, TU Gerngross Protein expression and purification 46 (2), 179-188, 2006 | 17 | 2006 |
Development of a high cell density transient CHO platform yielding mAb titers greater than 2 g/L in only 7 days MG Schmitt, RN White, GC Barnard Biotechnology progress 36 (6), e3047, 2020 | 14 | 2020 |
Polymer‐mediated flocculation of transient CHO cultures as a simple, high throughput method to facilitate antibody discovery MG Schmitt, Y Rajendra, MD Hougland, JS Boyles, GC Barnard Biotechnology Progress 33 (5), 1393-1400, 2017 | 6 | 2017 |
Expressing antigen binding fragments with high titers in a targeted integration CHO host by optimizing expression vector gene copy numbers and position: A case study D Tang, J Gunson, E Tran, C Lam, A Shen, B Snedecor, G Barnard, ... Biotechnology Progress 38 (6), e3290, 2022 | 2 | 2022 |
Recombinant adeno‐associated virus production evaluation in Chinese hamster ovary cells TM Cao, D Chen, GC Barnard, A Shen Biotechnology and Bioengineering 121 (1), 395-402, 2024 | 1 | 2024 |