| Hydroxycarbamide in very young children with sickle-cell anaemia: a multicentre, randomised, controlled trial (BABY HUG) WC Wang, RE Ware, ST Miller, RV Iyer, JF Casella, CP Minniti, S Rana, ... The Lancet 377 (9778), 1663-1672, 2011 | 770 | 2011 |
| A dideazatetrahydrofolate analog lacking a chiral center at C-6: N-[4-[2-(2-amino-3, 4-dihydro-4-oxo-7H-pyrrolo [2, 3-d] pyrimidin-5yl) ethyl [benzoyl]-L-glutamic acid is an … EC Taylor, D Kuhnt, C Shih, SM Rinzel, GB Grindey, J Barredo, ... Journal of medicinal chemistry 35 (23), 4450-4454, 1992 | 356 | 1992 |
| All Patients With the T(11; 16)(q23; p13.3) That Involves MLL and CBP Have Treatment-Related Hematologic Disorders JD Rowley, S Reshmi, O Sobulo, T Musvee, J Anastasi, S Raimondi, ... Blood, The Journal of the American Society of Hematology 90 (2), 535-541, 1997 | 286 | 1997 |
| Pleuropulmonary blastoma: a marker for familial disease JR Priest, J Watterson, L Strong, V Huff, WG Woods, RL Byrd, SH Friend, ... The Journal of pediatrics 128 (2), 220-224, 1996 | 257 | 1996 |
| Differences in folylpolyglutamate synthetase and dihydrofolate reductase expression in human B-lineage versus T-lineage leukemic lymphoblasts: mechanisms for lineage … AJ Galpin, JD Schuetz, E Masson, Y Yanishevski, TW Synold, JC Barredo, ... Molecular pharmacology 52 (1), 155-163, 1997 | 157 | 1997 |
| Cytotoxic effect of 5-aminoimidazole-4-carboxamide-1-β-4-ribofuranoside (AICAR) on childhood acute lymphoblastic leukemia (ALL) cells: implication for targeted therapy TK Sengupta, GM Leclerc, TT Hsieh-Kinser, GJ Leclerc, I Singh, ... Molecular cancer 6, 1-12, 2007 | 145 | 2007 |
| Differences in constitutive and post-methotrexate folylpolyglutamate synthetase activity in B-lineage and T-lineage leukemia JC Barredo, TW Synold, J Laver, MV Relling, CH Pui, DG Priest, ... | 140 | 1994 |
| Isolated CNS relapse of acute lymphoblastic leukemia treated with intensive systemic chemotherapy and delayed CNS radiation: a pediatric oncology group study JC Barredo, M Devidas, SJ Lauer, A Billett, MA Marymont, J Pullen, ... Journal of clinical oncology 24 (19), 3142-3149, 2006 | 138 | 2006 |
| Metformin induces apoptosis through AMPK-dependent inhibition of UPR signaling in ALL lymphoblasts GM Leclerc, GJ Leclerc, JN Kuznetsov, J DeSalvo, JC Barredo PloS one 8 (8), e74420, 2013 | 117 | 2013 |
| Serum ferritin level changes in children with sickle cell disease on chronic blood transfusion are nonlinear and are associated with iron load and liver injury TV Adamkiewicz, MR Abboud, C Paley, N Olivieri, M Kirby-Allen, ... Blood, The Journal of the American Society of Hematology 114 (21), 4632-4638, 2009 | 112 | 2009 |
| AMPK-induced activation of Akt by AICAR is mediated by IGF-1R dependent and independent mechanisms in acute lymphoblastic leukemia GM Leclerc, GJ Leclerc, G Fu, JC Barredo Journal of molecular signaling 5, 1-13, 2010 | 108 | 2010 |
| AMPK and Akt determine apoptotic cell death following perturbations of one-carbon metabolism by regulating ER stress in acute lymphoblastic leukemia JN Kuznetsov, GJ Leclerc, GM Leclerc, JC Barredo Molecular cancer therapeutics 10 (3), 437-447, 2011 | 100 | 2011 |
| Real-time RT-PCR analysis of mRNA decay: half-life of Beta-actin mRNA in human leukemia CCRF-CEM and Nalm-6 cell lines GJ Leclerc, GM Leclerc, JC Barredo Cancer cell international 2, 1-5, 2002 | 97 | 2002 |
| Endoplasmic reticulum stress induced by 2-deoxyglucose but not glucose starvation activates AMPK through CaMKKβ leading to autophagy H Xi, JC Barredo, JR Merchan, TJ Lampidis Biochemical Pharmacology 85 (10), 1463-1477, 2013 | 81 | 2013 |
| Inhibition of Akt potentiates 2-DG–Induced apoptosis via downregulation of UPR in acute lymphoblastic leukemia J DeSalvo, JN Kuznetsov, J Du, GM Leclerc, GJ Leclerc, TJ Lampidis, ... Molecular cancer research 10 (7), 969-978, 2012 | 74 | 2012 |
| Determinants of antifolate cytotoxicity: folylpolyglutamate synthetase activity during cellular proliferation and development. J Barredo, RG Moran Molecular pharmacology 42 (4), 687-694, 1992 | 74 | 1992 |
| Management of paranasal sinus malignancy TA Day, RA Beas, RJ Schlosser, BA Woodworth, J Barredo, AK Sharma, ... Current treatment options in oncology 6, 3-18, 2005 | 70 | 2005 |
| The pediatric hydroxyurea phase III clinical trial (BABY HUG): challenges of study design BW Thompson, ST Miller, ZR Rogers, RC Rees, RE Ware, MA Waclawiw, ... Pediatric blood & cancer 54 (2), 250-255, 2010 | 69 | 2010 |
| Outcomes after HLA-matched sibling transplantation or chemotherapy in children with acute lymphoblastic leukemia in a second remission after an isolated central nervous system … M Eapen, MJ Zhang, M Devidas, E Raetz, JC Barredo, AK Ritchey, ... Leukemia 22 (2), 281-286, 2008 | 68 | 2008 |
| Adjustment of children with cancer and their caregivers: moderating influences of family functioning. BF Fuemmeler, RT Brown, L Williams, J Barredo Families, Systems, & Health 21 (3), 263, 2003 | 65 | 2003 |
