A synthetic lethal drug combination mimics glucose deprivation–induced cancer cell death in the presence of glucose JH Joly, A Delfarah, PS Phung, S Parrish, NA Graham Journal of Biological Chemistry 295 (5), 1350-1365, 2020 | 64 | 2020 |
Inhibition of nucleotide synthesis promotes replicative senescence of human mammary epithelial cells A Delfarah, S Parrish, JA Junge, J Yang, F Seo, S Li, J Mac, P Wang, SE ... Journal of Biological Chemistry 294 (27), 10564-10578, 2019 | 39 | 2019 |
Deamidation shunts RelA from mediating inflammation to aerobic glycolysis J Zhao, M Tian, S Zhang, A Delfarah, R Gao, Y Rao, AC Savas, A Lu, ... Cell metabolism 31 (5), 937-955. e7, 2020 | 23 | 2020 |
Multi-omics microsampling for the profiling of lifestyle-associated changes in health X Shen, R Kellogg, DJ Panyard, N Bararpour, KE Castillo, ... Nature Biomedical Engineering 8 (1), 11-29, 2024 | 22 | 2024 |
AKT but not MYC promotes reactive oxygen species-mediated cell death in oxidative culture D Zheng, JH Sussman, MP Jeon, ST Parrish, MA MacMullan, A Delfarah, ... Journal of cell science 133 (7), jcs239277, 2020 | 12 | 2020 |
Elucidating tumor-stromal metabolic crosstalk in colorectal cancer through integration of constraint-based models and LC-MS metabolomics J Wang, A Delfarah, PE Gelbach, E Fong, P Macklin, SM Mumenthaler, ... Metabolic engineering 69, 175-187, 2022 | 8 | 2022 |
Bladder cancer cells shift rapidly and spontaneously to cisplatin-resistant oxidative phosphorylation that is trackable in real time T Xu, JA Junge, A Delfarah, YT Lu, C Arnesano, M Iqbal, K Delijani, ... Scientific Reports 12 (1), 5518, 2022 | 7 | 2022 |
Identification of a proteomic signature of senescence in primary human mammary epithelial cells A Delfarah, NG Hartel, DQ Zheng, J Yang, NA Graham Journal of Proteome Research 20 (11), 5169-5179, 2021 | 6 | 2021 |
Inhibition of nucleotide synthesis mediates replicative senescence of human mammary epithelial cells A Delfarah, S Parrish, J Yang, F Seo, S Li, P Wang, NA Graham BioRxiv, 423665, 2018 | 2 | 2018 |
Drug mechanism enrichment analysis improves prioritization of therapeutics for repurposing BB Garana, JH Joly, A Delfarah, H Hong, NA Graham BMC bioinformatics 24 (1), 215, 2023 | | 2023 |
Multi-Omics Reveals That AKT but Not MYC Promotes Reactive Oxygen Species-Mediated Cell Death in Oxidative Culture DQ Zheng, JH Sussman, PJ Jeon, S Parrish, M MacMullan, A Delfarah, ... 2020 Virtual AIChE Annual Meeting, 2020 | | 2020 |
Discovery of senescence biomarkers and senolytic drugs by proteomic profiling A Delfarah, DQ Zheng, JH Joly, J Yang, NA Graham bioRxiv, 2020.09. 22.309351, 2020 | | 2020 |
Metabolomic and Proteomic Approaches to Understanding Senescence and Aging in Mammary Epithelial Cells A Delfarah University of Southern California, 2020 | | 2020 |
Transition to and from a cancer stem-like state is marked by rapid metabolic shifts that are observable in real time using fluorescence lifetime imaging microscopy (FLIM) T Xu, C Arnesano, A Delfarah, Z Luo, K Delijani, E Hodara, P Farnham, ... Cancer Research 79 (13_Supplement), 5282-5282, 2019 | | 2019 |
Metabolomics Reveals That Inhibition of Nucleotide Synthesis Underlies Senescence of Human Mammary Epithelial Cells A Delfarah, S Parrish, J Yang, F Seo, S Li, P Wang, N Graham 2018 AIChE Annual Meeting, 2018 | | 2018 |