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Lars Fritsche
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A global reference for human genetic variation
1000 Genomes Project Consortium
Nature 526 (7571), 68, 2015
14429*2015
Association studies of up to 1.2 million individuals yield new insights into the genetic etiology of tobacco and alcohol use
M Liu, Y Jiang, R Wedow, Y Li, DM Brazel, F Chen, G Datta, ...
Nature genetics 51 (2), 237-244, 2019
14332019
A large genome-wide association study of age-related macular degeneration highlights contributions of rare and common variants
LG Fritsche, W Igl, JNC Bailey, F Grassmann, S Sengupta, ...
Nature genetics 48 (2), 134-143, 2016
13852016
Efficiently controlling for case-control imbalance and sample relatedness in large-scale genetic association studies
W Zhou, JB Nielsen, LG Fritsche, R Dey, ME Gabrielsen, BN Wolford, ...
Nature genetics 50 (9), 1335-1341, 2018
9782018
Hypothetical LOC387715 is a second major susceptibility gene for age-related macular degeneration, contributing independently of complement factor H to disease risk
A Rivera, SA Fisher, LG Fritsche, CN Keilhauer, P Lichtner, T Meitinger, ...
Human molecular genetics 14 (21), 3227-3236, 2005
9382005
Seven new loci associated with age-related macular degeneration.
LG Fritsche, W Chen, M Schu, BL Yaspan, Y Yu, G Thorleifsson, DJ Zack, ...
Nature genetics 45 (4), 433-9, 439e1-2, 2013
853*2013
Global prevalence of post-coronavirus disease 2019 (COVID-19) condition or long COVID: a meta-analysis and systematic review
C Chen, SR Haupert, L Zimmermann, X Shi, LG Fritsche, B Mukherjee
The Journal of infectious diseases 226 (9), 1593-1607, 2022
8092022
Biobank-driven genomic discovery yields new insight into atrial fibrillation biology
JB Nielsen, RB Thorolfsdottir, LG Fritsche, W Zhou, MW Skov, SE Graham, ...
Nature genetics 50 (9), 1234-1239, 2018
5972018
Age-related macular degeneration: genetics and biology coming together
LG Fritsche, RN Fariss, D Stambolian, GR Abecasis, CA Curcio, ...
Annual review of genomics and human genetics 15, 151-171, 2014
5412014
Exome-wide association study of plasma lipids in> 300,000 individuals
DJ Liu, GM Peloso, H Yu, AS Butterworth, X Wang, A Mahajan, ...
Nature genetics 49 (12), 1758-1766, 2017
5292017
A genome-wide association study with 1,126,563 individuals identifies new risk loci for Alzheimer’s disease
DP Wightman, IE Jansen, JE Savage, AA Shadrin, S Bahrami, D Holland, ...
Nature genetics 53 (9), 1276-1282, 2021
5122021
Shared genetic origin of asthma, hay fever and eczema elucidates allergic disease biology
MA Ferreira, JM Vonk, H Baurecht, I Marenholz, C Tian, JD Hoffman, ...
Nature genetics 49 (12), 1752, 2017
4922017
Age-related macular degeneration is associated with an unstable ARMS2 (LOC387715) mRNA
LG Fritsche, T Loenhardt, A Janssen, SA Fisher, A Rivera, CN Keilhauer, ...
Nature genetics 40 (7), 892-896, 2008
4812008
Systemic complement activation in age-related macular degeneration
HPN Scholl, PC Issa, M Walier, S Janzer, B Pollok-Kopp, F Börncke, ...
PloS one 3 (7), 2008
4662008
Deciphering osteoarthritis genetics across 826,690 individuals from 9 populations
CG Boer, K Hatzikotoulas, L Southam, L Stefánsdóttir, Y Zhang, ...
Cell 184 (18), 4784-4818. e17, 2021
2672021
Characteristics Associated With Racial/Ethnic Disparities in COVID-19 Outcomes in an Academic Health Care System
T Gu, JA Mack, M Salvatore, SP Sankar, TS Valley, K Singh, ...
JAMA Network Open 3 (10), e2025197-e2025197, 2020
266*2020
An imbalance of human complement regulatory proteins CFHR1, CFHR3 and factor H influences risk for age-related macular degeneration (AMD)
LG Fritsche, N Lauer, A Hartmann, S Stippa, CN Keilhauer, M Oppermann, ...
Human molecular genetics 19 (23), 4694-4704, 2010
2332010
Defective complement control of factor H (Y402H) and FHL-1 in age-related macular degeneration
C Skerka, N Lauer, AAWA Weinberger, CN Keilhauer, J Sühnel, R Smith, ...
Molecular immunology 44 (13), 3398-3406, 2007
2242007
Retinal transcriptome and eQTL analyses identify genes associated with age-related macular degeneration
R Ratnapriya, OA Sosina, MR Starostik, M Kwicklis, RJ Kapphahn, ...
Nature genetics 51 (4), 606-610, 2019
2182019
CRX ChIP-seq reveals the cis-regulatory architecture of mouse photoreceptors
JC Corbo, KA Lawrence, M Karlstetter, CA Myers, M Abdelaziz, W Dirkes, ...
Genome research 20 (11), 1512-1525, 2010
2132010
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