| Targeting the STAT3 signaling pathway in cancer: role of synthetic and natural inhibitors KS Siveen, S Sikka, R Surana, X Dai, J Zhang, AP Kumar, BKH Tan, ... Biochimica et Biophysica Acta (BBA)-reviews on cancer 1845 (2), 136-154, 2014 | 764 | 2014 |
| Ageing and the telomere connection: An intimate relationship with inflammation J Zhang, G Rane, X Dai, MK Shanmugam, F Arfuso, RP Samy, MKP Lai, ... Ageing research reviews 25, 55-69, 2016 | 368 | 2016 |
| Potential role of signal transducer and activator of transcription (STAT) 3 signaling pathway in inflammation, survival, proliferation and invasion of hepatocellular carcinoma A Subramaniam, MK Shanmugam, E Perumal, F Li, A Nachiyappan, X Dai, ... Biochimica et Biophysica Acta (BBA)-Reviews on Cancer 1835 (1), 46-60, 2013 | 347 | 2013 |
| Ursolic acid in cancer prevention and treatment: molecular targets, pharmacokinetics and clinical studies MK Shanmugam, X Dai, AP Kumar, BKH Tan, G Sethi, A Bishayee Biochemical pharmacology 85 (11), 1579-1587, 2013 | 341 | 2013 |
| Systematic immunotherapy target discovery using genome-scale in vivo CRISPR screens in CD8 T cells MB Dong, G Wang, RD Chow, L Ye, L Zhu, X Dai, JJ Park, HR Kim, ... Cell 178 (5), 1189-1204. e23, 2019 | 226 | 2019 |
| Targeting TNF-related apoptosis-inducing ligand (TRAIL) receptor by natural products as a potential therapeutic approach for cancer therapy X Dai, J Zhang, F Arfuso, A Chinnathambi, ME Zayed, SA Alharbi, ... Experimental Biology and Medicine 240 (6), 760-773, 2015 | 186 | 2015 |
| Development of a novel azaspirane that targets the Janus kinase-signal transducer and activator of transcription (STAT) pathway in hepatocellular carcinoma in vitro and in vivo CD Mohan, H Bharathkumar, KC Bulusu, V Pandey, S Rangappa, ... Journal of Biological Chemistry 289 (49), 34296-34307, 2014 | 163 | 2014 |
| In vivo CRISPR screening in CD8 T cells with AAV–Sleeping Beauty hybrid vectors identifies membrane targets for improving immunotherapy for glioblastoma L Ye, JJ Park, MB Dong, Q Yang, RD Chow, L Peng, Y Du, J Guo, X Dai, ... Nature biotechnology 37 (11), 1302-1313, 2019 | 136 | 2019 |
| One-step generation of modular CAR-T cells with AAV–Cpf1 X Dai, JJ Park, Y Du, HR Kim, G Wang, Y Errami, S Chen Nature Methods 16 (3), 247-254, 2019 | 134 | 2019 |
| Ascochlorin, an isoprenoid antibiotic inhibits growth and invasion of hepatocellular carcinoma by targeting STAT3 signaling cascade through the induction of PIAS3 X Dai, KS Ahn, C Kim, KS Siveen, TH Ong, MK Shanmugam, F Li, J Shi, ... Molecular oncology 9 (4), 818-833, 2015 | 106 | 2015 |
| Multiplexed activation of endogenous genes by CRISPRa elicits potent antitumor immunity G Wang, RD Chow, Z Bai, L Zhu, Y Errami, X Dai, MB Dong, L Ye, ... Nature Immunology 20 (11), 1494-1505, 2019 | 92 | 2019 |
| Mapping a functional cancer genome atlas of tumor suppressors in mouse liver using AAV-CRISPR–mediated direct in vivo screening G Wang, RD Chow, L Ye, CD Guzman, X Dai, MB Dong, F Zhang, ... Science advances 4 (2), eaao5508, 2018 | 86 | 2018 |
| Ascochlorin enhances the sensitivity of doxorubicin leading to the reversal of epithelial-to-mesenchymal transition in hepatocellular carcinoma X Dai, KS Ahn, LZ Wang, C Kim, A Deivasigamni, F Arfuso, JY Um, ... Molecular Cancer Therapeutics 15 (12), 2966-2976, 2016 | 86 | 2016 |
| CRISPR-GEMM pooled mutagenic screening identifies KMT2D as a major modulator of immune checkpoint blockade G Wang, RD Chow, L Zhu, Z Bai, L Ye, F Zhang, PA Renauer, MB Dong, ... Cancer discovery 10 (12), 1912-1933, 2020 | 82 | 2020 |
| A genome-scale gain-of-function CRISPR screen in CD8 T cells identifies proline metabolism as a means to enhance CAR-T therapy L Ye, JJ Park, L Peng, Q Yang, RD Chow, MB Dong, SZ Lam, J Guo, ... Cell metabolism 34 (4), 595-614. e14, 2022 | 81 | 2022 |
| A novel anticancer agent, SKLB70359, inhibits human hepatic carcinoma cells proliferation via G0/G1 cell cycle arrest and apoptosis induction XY Dai, XX Zeng, F Peng, YY Han, HJ Lin, YZ Xu, T Zhou, G Xie, Y Deng, ... Cellular Physiology and Biochemistry 29 (1-2), 281-290, 2012 | 29 | 2012 |
| Mapping subcellular localizations of unannotated microproteins and alternative proteins with MicroID Z Na, X Dai, SJ Zheng, CJ Bryant, KH Loh, H Su, Y Luo, AF Buhagiar, ... Molecular cell 82 (15), 2900-2911. e7, 2022 | 22 | 2022 |
| Massively parallel knock-in engineering of human T cells X Dai, JJ Park, Y Du, Z Na, SZ Lam, RD Chow, PA Renauer, J Gu, S Xin, ... Nature Biotechnology 41 (9), 1239-1255, 2023 | 16 | 2023 |
| Synthesis and biological evaluation of novel acenaphthene derivatives as potential antitumor agents YM Xie, Y Deng, XY Dai, J Liu, L Ouyang, YQ Wei, YL Zhao Molecules 16 (3), 2519-2526, 2011 | 14 | 2011 |
| CRISPR-GEMM pooled mutagenic screening identifies KMT2D as a major modulator of immune checkpoint blockade. Cancer Discov. 2020; 10: 1912–1933. doi: 10.1158/2159-8290 G Wang, RD Chow, L Zhu, Z Bai, L Ye, F Zhang, PA Renauer, MB Dong, ... CD-19-1448.[Europe PMC free article][Abstract][CrossRef][Google Scholar], 0 | 11 | |
