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Lori Ferrins
Lori Ferrins
Research Associate Professor, Northeastern University
Verified email at northeastern.edu
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Cited by
Cited by
Year
SARS-CoV-2 infects the human kidney and drives fibrosis in kidney organoids
J Jansen, KC Reimer, JS Nagai, FS Varghese, GJ Overheul, M de Beer, ...
Cell Stem Cell 29 (2), 217-231. e8, 2022
1652022
PAINS: Relevance to tool compound discovery and fragment-based screening
JB Baell, L Ferrins, H Falk, G Nikolakopoulos
Australian Journal of Chemistry 66 (12), 1483-1494, 2013
962013
Pyridyl Benzamides as a Novel Class of Potent Inhibitors for the Kinetoplastid Trypanosoma brucei
L Ferrins, M Gazdik, R Rahmani, S Varghese, ML Sykes, AJ Jones, ...
Journal of medicinal chemistry 57 (15), 6393-6402, 2014
582014
Nuisance compounds in cellular assays
JL Dahlin, DS Auld, I Rothenaigner, S Haney, JZ Sexton, JWM Nissink, ...
Cell chemical biology 28 (3), 356-370, 2021
432021
Drug discovery and human African trypanosomiasis: a disease less neglected?
L Ferrins, R Rahmani, JB Baell
Future medicinal chemistry 5 (15), 1801-1841, 2013
392013
Hit-to-lead optimization of a novel class of potent, broad-spectrum trypanosomacides
S Russell, R Rahmani, AJ Jones, HL Newson, K Neilde, I Cotillo, ...
Journal of medicinal chemistry 59 (21), 9686-9720, 2016
382016
3-(Oxazolo [4, 5-b] pyridin-2-yl) anilides as a novel class of potent inhibitors for the kinetoplastid Trypanosoma brucei, the causative agent for human African trypanosomiasis
L Ferrins, R Rahmani, ML Sykes, AJ Jones, VM Avery, E Teston, ...
European journal of medicinal chemistry 66, 450-465, 2013
382013
Open Science Discovery of Potent Non-Covalent SARS-CoV-2 Main Protease Inhibitors
COVID Moonshot Consortium, H Achdout, A Aimon, DS Alonzi, R Arbon, ...
BioRxiv, 2020.10. 29.339317, 2020
352020
Potent and selective covalent inhibition of the papain-like protease from SARS-CoV-2
BC Sanders, S Pokhrel, AD Labbe, II Mathews, CJ Cooper, RB Davidson, ...
Nature communications 14 (1), 1733, 2023
312023
A diverse view of science to catalyse change
CA Urbina-Blanco, SZ Jilani, IR Speight, MJ Bojdys, T Friscic, JF Stoddart, ...
Journal of the American Chemical Society 142 (34), 14393-14396, 2020
312020
Metabolomics and lipidomics reveal perturbation of sphingolipid metabolism by a novel anti-trypanosomal 3-(oxazolo[4,5-b]pyridine-2-yl)anilide
D Stoessel, CJ Nowell, AJ Jones, L Ferrins, KM Ellis, J Riley, R Rahmani, ...
Metabolomics 12, 1-14, 2016
292016
Improvement of aqueous solubility of lapatinib-derived analogues: identification of a quinolinimine lead for human African trypanosomiasis drug development
KA Bachovchin, A Sharma, S Bag, DM Klug, KM Schneider, B Singh, ...
Journal of medicinal chemistry 62 (2), 665-687, 2018
272018
6-Arylpyrazine-2-carboxamides: A New Core for Trypanosoma brucei Inhibitors
R Rahmani, K Ban, AJ Jones, L Ferrins, D Ganame, ML Sykes, VM Avery, ...
Journal of medicinal chemistry 58 (17), 6753-6765, 2015
252015
Open science discovery of potent noncovalent SARS-CoV-2 main protease inhibitors
ML Boby, D Fearon, M Ferla, M Filep, L Koekemoer, MC Robinson, ...
Science 382 (6671), eabo7201, 2023
212023
Scaffold and parasite hopping: discovery of new protozoal proliferation inhibitors
B Singh, JA Bernatchez, LI McCall, CM Calvet, J Ackermann, JM Souza, ...
ACS Medicinal Chemistry Letters 11 (3), 249-257, 2020
172020
The importance of collaboration between industry, academics, and nonprofits in tropical disease drug discovery
L Ferrins, MP Pollastri
ACS infectious diseases 4 (4), 445-448, 2017
172017
Discovery of Potent N-Ethylurea Pyrazole Derivatives as Dual Inhibitors of Trypanosoma brucei and Trypanosoma cruzi
S Varghese, R Rahmani, S Russell, GS Deora, L Ferrins, A Toynton, ...
ACS Medicinal Chemistry Letters 11 (3), 278-285, 2019
152019
Optimization of Physicochemical Properties for 4-Anilinoquinoline Inhibitors of Plasmodium falciparum Proliferation
N Mehta, L Ferrins, SE Leed, RJ Sciotti, MP Pollastri
ACS infectious diseases 4 (4), 577-591, 2018
142018
Selectivity and Physicochemical Optimization of Repurposed Pyrazolo[1,5-b]pyridazines for the Treatment of Human African Trypanosomiasis
WF Tear, S Bag, R Diaz-Gonzalez, G Ceballos-Pérez, DI Rojas-Barros, ...
Journal of Medicinal Chemistry 63 (2), 756-783, 2019
132019
Hit-to-lead optimization of benzoxazepinoindazoles as human African trypanosomiasis therapeutics
DM Klug, L Tschiegg, R Diaz, D Rojas-Barros, G Perez-Moreno, ...
Journal of medicinal chemistry 63 (5), 2527-2546, 2019
112019
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