| An ultrapotent synthetic nanobody neutralizes SARS-CoV-2 by stabilizing inactive Spike M Schoof, B Faust, RA Saunders, S Sangwan, V Rezelj, N Hoppe, ... Science 370 (6523), 1473-1479, 2020 | 366 | 2020 |
| Mapping the conformational landscape of a dynamic enzyme by multitemperature and XFEL crystallography DA Keedy, LR Kenner, M Warkentin, RA Woldeyes, JB Hopkins, ... Elife 4, 2015 | 170 | 2015 |
| The protein shells of bacterial microcompartment organelles TO Yeates, MC Thompson, TA Bobik Current opinion in structural biology 21 (2), 223-231, 2011 | 159 | 2011 |
| Fragment binding to the Nsp3 macrodomain of SARS-CoV-2 identified through crystallographic screening and computational docking M Schuller, GJ Correy, S Gahbauer, D Fearon, T Wu, RE Díaz, ID Young, ... Science advances 7 (16), eabf8711, 2021 | 126 | 2021 |
| Computational design of a modular protein sense-response system AA Glasgow, YM Huang, DJ Mandell, M Thompson, R Ritterson, ... Science 366 (6468), 1024-1028, 2019 | 100 | 2019 |
| Ensemble-based enzyme design can recapitulate the effects of laboratory directed evolution in silico A Broom, RV Rakotoharisoa, MC Thompson, N Zarifi, E Nguyen, ... Nature communications 11 (1), 4808, 2020 | 80 | 2020 |
| Temperature-jump solution X-ray scattering reveals distinct motions in a dynamic enzyme MC Thompson, BA Barad, AM Wolff, HS Cho, F Schotte, DMC Schwarz, ... Nature chemistry 11 (11), 1058-1066, 2019 | 73 | 2019 |
| Mix-and-inject XFEL crystallography reveals gated conformational dynamics during enzyme catalysis M Dasgupta, D Budday, SHP De Oliveira, P Madzelan, ... Proceedings of the National Academy of Sciences 116 (51), 25634-25640, 2019 | 61 | 2019 |
| Expanding the space of protein geometries by computational design of de novo fold families X Pan, MC Thompson, Y Zhang, L Liu, JS Fraser, MJS Kelly, T Kortemme Science 369 (6507), 1132-1136, 2020 | 52 | 2020 |
| An allosteric model for control of pore opening by substrate binding in the EutL microcompartment shell protein MC Thompson, D Cascio, DJ Leibly, TO Yeates Protein Science 24 (6), 956-975, 2015 | 38 | 2015 |
| Comparing serial X-ray crystallography and microcrystal electron diffraction (MicroED) as methods for routine structure determination from small macromolecular crystals AM Wolff, ID Young, RG Sierra, AS Brewster, MW Martynowycz, E Nango, ... IUCrJ 7 (2), 306-323, 2020 | 36 | 2020 |
| Structure of a novel 13 nm dodecahedral nanocage assembled from a redesigned bacterial microcompartment shell protein J Jorda, DJ Leibly, MC Thompson, TO Yeates Chemical Communications 52 (28), 5041-5044, 2016 | 32 | 2016 |
| Advances in methods for atomic resolution macromolecular structure determination MC Thompson, TO Yeates, JA Rodriguez F1000Research 9, 2020 | 31 | 2020 |
| Structure of a bacterial microcompartment shell protein bound to a cobalamin cofactor MC Thompson, CS Crowley, J Kopstein, TA Bobik, TO Yeates Acta Crystallographica Section F: Structural Biology Communications 70 (12 …, 2014 | 29 | 2014 |
| Flexibility and design: conformational heterogeneity along the evolutionary trajectory of a redesigned ubiquitin JT Biel, MC Thompson, CN Cunningham, JE Corn, JS Fraser Structure 25 (5), 739-749. e3, 2017 | 27 | 2017 |
| Identification of a unique Fe-S cluster binding site in a glycyl-radical type microcompartment shell protein MC Thompson, NM Wheatley, J Jorda, MR Sawaya, SD Gidaniyan, ... Journal of molecular biology 426 (19), 3287-3304, 2014 | 26 | 2014 |
| Allosteric Inhibitors, Crystallography, and Comparative Analysis Reveal Network of Coordinated Movement across Human Herpesvirus Proteases TM Acker, JE Gable, MF Bohn, P Jaishankar, MC Thompson, JS Fraser, ... Journal of the American Chemical Society 139 (34), 11650-11653, 2017 | 18 | 2017 |
| Mapping Protein Dynamics at High Spatial Resolution with Temperature-Jump X-ray Crystallography AM Wolff, E Nango, ID Young, AS Brewster, M Kubo, T Nomura, ... BioRxiv, 2022.06. 10.495662, 2022 | 14 | 2022 |
| Microfocus diffraction from different regions of a protein crystal: structural variations and unit-cell polymorphism MC Thompson, D Cascio, TO Yeates Acta Crystallographica Section D: Structural Biology 74 (5), 2018 | 14 | 2018 |
| Accurate positioning of functional residues with robotics-inspired computational protein design C Krivacic, K Kundert, X Pan, RA Pache, L Liu, S O Conchúir, ... Proceedings of the National Academy of Sciences 119 (11), e2115480119, 2022 | 8 | 2022 |
James S. FraserProfessor, University of California San FranciscoVerified email at ucsf.edu
