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Nicholas Agard
Nicholas Agard
Dept of Antibody Engineering, Genentech
Verified email at gene.com
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Cited by
Year
A strain-promoted [3+ 2] azide− alkyne cycloaddition for covalent modification of biomolecules in living systems
NJ Agard, JA Prescher, CR Bertozzi
Journal of the American Chemical Society 126 (46), 15046-15047, 2004
33552004
A strain-promoted [3+ 2] azide− alkyne cycloaddition for covalent modification of biomolecules in living systems
NJ Agard, JA Prescher, CR Bertozzi
Journal of the American Chemical Society 126 (46), 15046-15047, 2004
33552004
Copper-free click chemistry for dynamic in vivo imaging
JM Baskin, JA Prescher, ST Laughlin, NJ Agard, PV Chang, IA Miller, A Lo, ...
Proceedings of the National Academy of Sciences 104 (43), 16793-16797, 2007
22472007
A comparative study of bioorthogonal reactions with azides
NJ Agard, JM Baskin, JA Prescher, A Lo, CR Bertozzi
ACS chemical biology 1 (10), 644-648, 2006
9562006
Copper-free click chemistry in living animals
PV Chang, JA Prescher, EM Sletten, JM Baskin, IA Miller, NJ Agard, A Lo, ...
Proceedings of the National Academy of Sciences 107 (5), 1821-1826, 2010
7582010
Second-generation difluorinated cyclooctynes for copper-free click chemistry
JA Codelli, JM Baskin, NJ Agard, CR Bertozzi
Journal of the American Chemical Society 130 (34), 11486-11493, 2008
7312008
Discovery of aminoacyl-tRNA synthetase activity through cell-surface display of noncanonical amino acids
AJ Link, MKS Vink, NJ Agard, JA Prescher, CR Bertozzi, DA Tirrell
Proceedings of the National Academy of Sciences 103 (27), 10180-10185, 2006
2972006
Inflammatory stimuli regulate caspase substrate profiles
NJ Agard, D Maltby, JA Wells
Molecular & Cellular Proteomics 9 (5), 880-893, 2010
2142010
Chemical approaches to perturb, profile, and perceive glycans
NJ Agard, CR Bertozzi
Accounts of chemical research 42 (6), 788-797, 2009
1792009
Metabolic labeling of glycans with azido sugars for visualization and glycoproteomics
ST Laughlin, NJ Agard, JM Baskin, IS Carrico, PV Chang, AS Ganguli, ...
Methods in enzymology 415, 230-250, 2006
1782006
The DegraBase: a database of proteolysis in healthy and apoptotic human cells
ED Crawford, JE Seaman, N Agard, GW Hsu, O Julien, S Mahrus, ...
Molecular & Cellular Proteomics 12 (3), 813-824, 2013
1522013
Global kinetic analysis of proteolysis via quantitative targeted proteomics
NJ Agard, S Mahrus, JC Trinidad, A Lynn, AL Burlingame, JA Wells
Proceedings of the National Academy of Sciences 109 (6), 1913-1918, 2012
1292012
Compositions and methods for modification of biomolecules
CR Bertozzi, NJ Agard, JA Prescher, JM Baskin
US Patent 7,807,619, 2010
1282010
Compositions and methods for modification of biomolecules
CR Bertozzi, NJ Agard, JA Prescher, JM Baskin
US Patent 7,807,619, 2010
1282010
3-Methoxycarbonyl-5-nitrophenyl boronic acid: high affinity diol recognition at neutral pH
HR Mulla, NJ Agard, A Basu
Bioorganic & medicinal chemistry letters 14 (1), 25-27, 2004
1152004
Methods for the proteomic identification of protease substrates
NJ Agard, JA Wells
Current opinion in chemical biology 13 (5-6), 503-509, 2009
812009
Antibody targeting of E3 ubiquitin ligases for receptor degradation
H Marei, WTK Tsai, YS Kee, K Ruiz, J He, C Cox, T Sun, S Penikalapati, ...
Nature 610 (7930), 182-189, 2022
752022
A Strain-Promoted [3 + 2] Azide−Alkyne Cycloaddition for Covalent Modification of Biomolecules in Living Systems [J. Am. Chem. Soc. 2004, 126, 15046−15047].
NJ Agard, JA Prescher, CR Bertozzi
Journal of the American Chemical Society 127 (31), 11196-11196, 2005
582005
Unraveling the mechanism of cell death induced by chemical fibrils
O Julien, M Kampmann, MC Bassik, JA Zorn, VJ Venditto, K Shimbo, ...
Nature chemical biology 10 (11), 969-976, 2014
552014
Fibrils colocalize caspase-3 with procaspase-3 to foster maturation
JA Zorn, DW Wolan, NJ Agard, JA Wells
Journal of Biological Chemistry 287 (40), 33781-33795, 2012
522012
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