Diverse functions of cationic Mn(III) N-substituted pyridylporphyrins, recognized as SOD mimics I Batinic-Haberle, Z Rajic, A Tovmasyan, JS Reboucas, X Ye, KW Leong, ... Free Radical Biology and Medicine 51 (5), 1035-1053, 2011 | 154 | 2011 |
Design of Mn porphyrins for treating oxidative stress injuries and their redox-based regulation of cellular transcriptional activities I Batinic-Haberle, I Spasojevic, HM Tse, A Tovmasyan, Z Rajic, ... Amino acids 42, 95-113, 2012 | 120 | 2012 |
A new SOD mimic, Mn(III) ortho N-butoxyethylpyridylporphyrin, combines superb potency and lipophilicity with low toxicity Z Rajic, A Tovmasyan, I Spasojevic, H Sheng, M Lu, AM Li, EB Gralla, ... Free Radical Biology and Medicine 52 (9), 1828-1834, 2012 | 91 | 2012 |
Hydantoin Derivatives of l- and d-amino acids: Synthesis and Evaluation of Their Antiviral and Antitumoral Activity Z Rajic, B Zorc, S Raic-Malic, K Ester, M Kralj, K Pavelic, J Balzarini, ... Molecules 11 (11), 837-848, 2006 | 82 | 2006 |
Radioprotection of the Brain White Matter by Mn(III) N-Butoxyethylpyridylporphyrin–Based Superoxide Dismutase Mimic MnTnBuOE-2-PyP5+ DH Weitzel, A Tovmasyan, KA Ashcraft, Z Rajic, T Weitner, C Liu, W Li, ... Molecular cancer therapeutics 14 (1), 70-79, 2015 | 74 | 2015 |
Differential coordination demands in Fe versus Mn water-soluble cationic metalloporphyrins translate into remarkably different aqueous redox chemistry and biology A Tovmasyan, T Weitner, H Sheng, MM Lu, Z Rajic, DS Warner, ... Inorganic chemistry 52 (10), 5677-5691, 2013 | 74 | 2013 |
The novel phosphoramidate derivatives of NSAID 3-hydroxypropylamides: synthesis, cytostatic and antiviral activity evaluations K Wittine, K Benci, Z Rajić, B Zorc, M Kralj, M Marjanović, K Pavelić, ... European journal of medicinal chemistry 44, 143-151, 2009 | 66 | 2009 |
Antioxidant activity of NSAID hydroxamic acids M Končič, Z Rajič, N Petrič, B Zorc Acta pharmaceutica 59 (2), 235-242, 2009 | 46 | 2009 |
A combination of two antioxidants (an SOD mimic and ascorbate) produces a pro-oxidative effect forcing Escherichia coli to adapt via induction of oxyR regulon I Batinic-Haberle, Z Rajic, L Benov Anti-Cancer Agents in Medicinal Chemistry (Formerly Current Medicinal …, 2011 | 44 | 2011 |
Methoxy-derivatization of alkyl chains increases the in vivo efficacy of cationic Mn porphyrins. Synthesis, characterization, SOD-like activity, and SOD-deficient E. coli study … AG Tovmasyan, Z Rajic, I Spasojevic, JS Reboucas, X Chen, D Salvemini, ... Dalton transactions 40 (16), 4111-4121, 2011 | 42 | 2011 |
Inhibition of glioblastoma cell proliferation, invasion, and mechanism of action of a novel hydroxamic acid hybrid molecule I Zhang, M Beus, U Stochaj, PU Le, B Zorc, Z Rajić, K Petrecca, ... Cell death discovery 4 (1), 41, 2018 | 38 | 2018 |
Primaquine-NSAID twin drugs: Synthesis, radical scavenging, antioxidant and Fe2+ chelating activity Z Rajić, M Zovko Končić, K Miloloža, I Perković, I Butula, F Bucar, B Zorc Acta pharmaceutica 60 (3), 325-337, 2010 | 38 | 2010 |
Bioavailability of metalloporphyrin-based SOD mimics is greatly influenced by a single charge residing on a Mn site I Spasojevic, I Kos, LT Benov, Z Rajic, D Fels, C Dedeugd, X Ye, ... Free radical research 45 (2), 188-200, 2011 | 35 | 2011 |
Harmicines− harmine and cinnamic acid hybrids as novel antiplasmodial hits I Perković, S Raić-Malić, D Fontinha, M Prudêncio, LP de Carvalho, ... European journal of medicinal chemistry 187, 111927, 2020 | 33 | 2020 |
The Novel Ketoprofen Amides – Synthesis and Biological Evaluation as Antioxidants, Lipoxygenase Inhibitors and Cytostatic Agents Z Rajić, D Hadjipavlou-Litina, E Pontiki, M Kralj, L Šuman, B Zorc Chemical Biology & Drug Design 75, 641-652, 2010 | 33 | 2010 |
Accumulation of porphyrin-based SOD mimics in mitochondria is proportional to their lipophilicity. S. cerevisiae study of ortho Mn (III) N-alkylpyridylporphyrins I Spasojevic, A Li, A Tovmasyan, Z Rajic, D Salvemini, D St Clair, ... SFRBM's 17th Annual Meeting, S199-S199, 2010 | 27 | 2010 |
Challenges encountered during development of Mn porphyrin-based, potent redox-active drug and superoxide dismutase mimic, MnTnBuOE-2-PyP5+, and its alkoxyalkyl analogues Z Rajic, A Tovmasyan, OL de Santana, IN Peixoto, I Spasojevic, ... Journal of Inorganic Biochemistry 169, 50-60, 2017 | 24 | 2017 |
Macromolecular prodrugs. XII. Primaquine conjugates: synthesis and preliminary antimalarial evaluation Z Rajić, G Kos, B Zorc, P Singh, S Singh Acta Pharmaceutica 59 (1), 107-115, 2009 | 21 | 2009 |
Novel Harmicines with Improved Potency against Plasmodium M Marinović, I Perković, D Fontinha, M Prudêncio, J Held, ... Molecules 25 (19), 4376, 2020 | 20 | 2020 |
Synthesis and biological evaluation of O-methyl and O-ethyl NSAID hydroxamic acids Z Rajić, I Perković, I Butula, B Zorc, D Hadjipavlou-Litina, E Pontiki, ... Journal of enzyme inhibition and medicinal chemistry 24, 1179-1187, 2009 | 20 | 2009 |