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James A.R. Dalton
James A.R. Dalton
Ronin Institute, NJ, USA
Verified email at ronininstitute.org - Homepage
Title
Cited by
Cited by
Year
An allosteric modulator to control endogenous G protein-coupled receptors with light
S Pittolo, X Gómez-Santacana, K Eckelt, X Rovira, J Dalton, C Goudet, ...
Nature chemical biology 10 (10), 813-815, 2014
1692014
An evaluation of automated homology modelling methods at low target–template sequence similarity
JAR Dalton, RM Jackson
Bioinformatics 23 (15), 1901-1908, 2007
1272007
New model of cystic fibrosis transmembrane conductance regulator proposes active channel-like conformation
J Dalton, O Kalid, M Schushan, N Ben-Tal, J Villà-Freixa
Journal of chemical information and modeling 52 (7), 1842-1853, 2012
862012
Illuminating phenylazopyridines to photoswitch metabotropic glutamate receptors: from the flask to the animals
X Gómez-Santacana, S Pittolo, X Rovira, M Lopez, C Zussy, JAR Dalton, ...
ACS central science 3 (1), 81-91, 2017
752017
Allosteric control of an asymmetric transduction in a G protein-coupled receptor heterodimer
J Liu, Z Zhang, D Moreno-Delgado, JAR Dalton, X Rovira, A Trapero, ...
Elife 6, e26985, 2017
562017
GNAO1 encephalopathy: further delineation of a severe neurodevelopmental syndrome affecting females
A Marcé-Grau, J Dalton, J López-Pisón, MC García-Jiménez, ...
Orphanet journal of rare diseases 11, 1-9, 2016
462016
Quantifying conformational changes in GPCRs: glimpse of a common functional mechanism
JAR Dalton, I Lans, J Giraldo
BMC bioinformatics 16, 1-15, 2015
462015
Artificial intelligence: a novel approach for drug discovery
Ó Díaz, JAR Dalton, J Giraldo
Trends in pharmacological sciences 40 (8), 550-551, 2019
452019
Structural insights into positive and negative allosteric regulation of a G protein-coupled receptor through protein-lipid interactions
A Bruzzese, C Gil, JAR Dalton, J Giraldo
Scientific reports 8 (1), 4456, 2018
452018
Structural assessment of agonist efficacy in the μ-opioid receptor: morphine and fentanyl elicit different activation patterns
A Ricarte, JAR Dalton, J Giraldo
Journal of Chemical Information and Modeling 61 (3), 1251-1274, 2021
432021
Calculation of helix packing angles in protein structures
JAR Dalton, I Michalopoulos, DR Westhead
Bioinformatics 19 (10), 1298-1299, 2003
382003
Homology-modelling protein–ligand interactions: allowing for ligand-induced conformational change
JAR Dalton, RM Jackson
Journal of molecular biology 399 (4), 645-661, 2010
322010
Distinct Dopamine D2 Receptor Antagonists Differentially Impact D2 Receptor Oligomerization
E Wouters, AR Marín, JAR Dalton, J Giraldo, C Stove
International journal of molecular sciences 20 (7), 1686, 2019
292019
Computational analysis of negative and positive allosteric modulator binding and function in metabotropic glutamate receptor 5 (in) activation
JAR Dalton, X Gomez-Santacana, A Llebaria, J Giraldo
Journal of chemical information and modeling 54 (5), 1476-1487, 2014
292014
Insights into adenosine A2A receptor activation through cooperative modulation of agonist and allosteric lipid interactions
A Bruzzese, JAR Dalton, J Giraldo
PLoS computational biology 16 (4), e1007818, 2020
242020
Synthesis toward Bivalent Ligands for the Dopamine D2 and Metabotropic Glutamate 5 Receptors
M Qian, E Wouters, JAR Dalton, MDP Risseeuw, RAJ Crans, C Stove, ...
Journal of Medicinal Chemistry 61 (18), 8212-8225, 2018
232018
Revealing the mechanism of agonist-mediated cannabinoid receptor 1 (CB1) activation and phospholipid-mediated allosteric modulation
Ó Díaz, JAR Dalton, J Giraldo
Journal of Medicinal Chemistry 62 (11), 5638-5654, 2019
222019
Rational design of a peptide capture agent for CXCL8 based on a model of the CXCL8: CXCR1 complex
D Helmer, I Rink, JAR Dalton, K Brahm, M Jöst, TM Nargang, W Blum, ...
RSC advances 5 (33), 25657-25668, 2015
212015
Shining light on an mGlu5 photoswitchable NAM: a theoretical perspective
J AR Dalton, I Lans, X Rovira, F Malhaire, X Gómez-Santacana, S Pittolo, ...
Current neuropharmacology 14 (5), 441-454, 2016
192016
Helix 3 acts as a conformational hinge in Class A GPCR activation: An analysis of interhelical interaction energies in crystal structures
I Lans, JAR Dalton, J Giraldo
Journal of structural biology 192 (3), 545-553, 2015
182015
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