| Accelerating novel candidate gene discovery in neurogenetic disorders via whole-exome sequencing of prescreened multiplex consanguineous families AM Alazami, N Patel, HE Shamseldin, S Anazi, MS Al-Dosari, F Alzahrani, ... Cell reports 10 (2), 148-161, 2015 | 449 | 2015 |
| Protein-induced photophysical changes to the amyloid indicator dye thioflavin T LS Wolfe, MF Calabrese, A Nath, DV Blaho, AD Miranker, Y Xiong Proceedings of the National Academy of Sciences 107 (39), 16863-16868, 2010 | 383 | 2010 |
| Design of stable α-helical arrays from an idealized TPR motif ERG Main, Y Xiong, MJ Cocco, L D'Andrea, L Regan Structure 11 (5), 497-508, 2003 | 367 | 2003 |
| BRCA1–BARD1 promotes RAD51-mediated homologous DNA pairing W Zhao, JB Steinfeld, F Liang, X Chen, DG Maranon, C Jian Ma, Y Kwon, ... Nature 550 (7676), 360-365, 2017 | 340 | 2017 |
| The crystal structure of yeast fatty acid synthase, a cellular machine with eight active sites working together IB Lomakin, Y Xiong, TA Steitz Cell 129 (2), 319-332, 2007 | 270 | 2007 |
| Structure of a prokaryotic virtual proton pump at 3.2 Å resolution Y Fang, H Jayaram, T Shane, L Kolmakova-Partensky, F Wu, C Williams, ... Nature 460 (7258), 1040-1043, 2009 | 253 | 2009 |
| MHF1-MHF2, a histone-fold-containing protein complex, participates in the Fanconi anemia pathway via FANCM TR Singh, D Saro, AM Ali, XF Zheng, C Du, MW Killen, A Sachpatzidis, ... Molecular cell 37 (6), 879-886, 2010 | 238 | 2010 |
| X-ray analysis of an RNA tetraplex (UGGGGU)4 with divalent Sr2+ ions at subatomic resolution (0.61 Å) J Deng, Y Xiong, M Sundaralingam Proceedings of the National Academy of Sciences 98 (24), 13665-13670, 2001 | 188 | 2001 |
| Functional landscape of SARS-CoV-2 cellular restriction L Martin-Sancho, MK Lewinski, L Pache, CA Stoneham, X Yin, ME Becker, ... Molecular cell 81 (12), 2656-2668. e8, 2021 | 170 | 2021 |
| IFT27, encoding a small GTPase component of IFT particles, is mutated in a consanguineous family with Bardet–Biedl syndrome MA Aldahmesh, Y Li, A Alhashem, S Anazi, H Alkuraya, M Hashem, ... Human molecular genetics 23 (12), 3307-3315, 2014 | 170 | 2014 |
| Mechanism of allosteric activation of SAMHD1 by dGTP X Ji, Y Wu, J Yan, J Mehrens, H Yang, M DeLucia, C Hao, ... Nature structural & molecular biology 20 (11), 1304-1309, 2013 | 164 | 2013 |
| Structural basis of evasion of cellular adaptive immunity by HIV-1 Nef X Jia, R Singh, S Homann, H Yang, J Guatelli, Y Xiong Nature structural & molecular biology 19 (7), 701-706, 2012 | 164 | 2012 |
| Nonstructural protein 1 of SARS-CoV-2 is a potent pathogenicity factor redirecting host protein synthesis machinery toward viral RNA S Yuan, L Peng, JJ Park, Y Hu, SC Devarkar, MB Dong, Q Shen, S Wu, ... Molecular cell 80 (6), 1055-1066. e6, 2020 | 159 | 2020 |
| Mechanism of transfer RNA maturation by CCA-adding enzyme without using an oligonucleotide template Y Xiong, TA Steitz Nature 430 (7000), 640-645, 2004 | 156 | 2004 |
| Crystal structures of the Bacillus stearothermophilus CCA-adding enzyme and its complexes with ATP or CTP F Li, Y Xiong, J Wang, HDD Cho, K Tomita, AM Weiner, TA Steitz Cell 111 (6), 815-824, 2002 | 151 | 2002 |
| Structural insight into the human immunodeficiency virus Vif SOCS box and its role in human E3 ubiquitin ligase assembly BJ Stanley, ES Ehrlich, L Short, Y Yu, Z Xiao, XF Yu, Y Xiong Journal of virology 82 (17), 8656-8663, 2008 | 149 | 2008 |
| Structural basis of cellular dNTP regulation by SAMHD1 X Ji, C Tang, Q Zhao, W Wang, Y Xiong Proceedings of the National Academy of Sciences 111 (41), E4305-E4314, 2014 | 148 | 2014 |
| Structural insight into HIV-1 restriction by MxB JL Fribourgh, HC Nguyen, KA Matreyek, FJD Alvarez, BJ Summers, ... Cell host & microbe 16 (5), 627-638, 2014 | 134 | 2014 |
| Structural insight into the mechanisms of enveloped virus tethering by tetherin H Yang, J Wang, X Jia, MW McNatt, T Zang, B Pan, W Meng, HW Wang, ... Proceedings of the National Academy of Sciences 107 (43), 18428-18432, 2010 | 131 | 2010 |
| Structure of a synaptic γδ resolvase tetramer covalently linked to two cleaved DNAs W Li, S Kamtekar, Y Xiong, GJ Sarkis, NDF Grindley, TA Steitz Science 309 (5738), 1210-1215, 2005 | 125 | 2005 |
