| Safety and tolerability of gene therapy with an adeno-associated virus (AAV) borne GAD gene for Parkinson's disease: an open label, phase I trial MG Kaplitt, A Feigin, C Tang, HL Fitzsimons, P Mattis, PA Lawlor, ... The Lancet 369 (9579), 2097-2105, 2007 | 1290 | 2007 |
| VEGF links hippocampal activity with neurogenesis, learning and memory L Cao, X Jiao, DS Zuzga, Y Liu, DM Fong, D Young, MJ During Nature genetics 36 (8), 827-835, 2004 | 1027 | 2004 |
| Environmental enrichment inhibits spontaneous apoptosis, prevents seizures and is neuroprotective D Young, PA Lawlor, P Leone, M Dragunow, MJ During Nature medicine 5 (4), 448-453, 1999 | 954 | 1999 |
| Brain-derived neurotrophic factor is reduced in Alzheimer's disease B Connor, D Young, Q Yan, RLM Faull, B Synek, M Dragunow Molecular brain research 49 (1-2), 71-81, 1997 | 715 | 1997 |
| An oral vaccine against NMDAR1 with efficacy in experimental stroke and epilepsy MJ During, CW Symes, PA Lawlor, J Lin, J Dunning, HL Fitzsimons, ... Science 287 (5457), 1453-1460, 2000 | 326 | 2000 |
| Long-term follow-up after gene therapy for canavan disease P Leone, D Shera, SWJ McPhee, JS Francis, EH Kolodny, LT Bilaniuk, ... Science translational medicine 4 (165), 165ra163-165ra163, 2012 | 293 | 2012 |
| Is c-Jun involved in nerve cell death following status epilepticus and hypoxic-ischaemic brain injury? M Dragunow, D Young, P Hughes, G MacGibbon, P Lawlor, K Singleton, ... Molecular brain research 18 (4), 347-352, 1993 | 268 | 1993 |
| Neuronal death and survival in two models of hypoxic-ischemic brain damage M Walton, B Connor, P Lawlor, D Young, E Sirimanne, P Gluckman, ... Brain research reviews 29 (2-3), 137-168, 1999 | 260 | 1999 |
| AAV-mediated hippocampal expression of short and long Homer 1 proteins differentially affect cognition and seizure activity in adult rats M Klugmann, CW Symes, CB Leichtlein, BK Klaussner, J Dunning, ... Molecular and Cellular Neuroscience 28 (2), 347-360, 2005 | 235 | 2005 |
| Quantitative comparison of expression with adeno-associated virus (AAV-2) brain-specific gene cassettes R Xu, CG Janson, M Mastakov, P Lawlor, D Young, A Mouravlev, ... Gene therapy 8 (17), 1323-1332, 2001 | 233 | 2001 |
| Peroral gene therapy of lactose intolerance using an adeno-associated virus vector MJ During, R Xu, D Young, MG Kaplitt, RS Sherwin, P Leone Nature medicine 4 (10), 1131-1135, 1998 | 208 | 1998 |
| AAV vector–mediated RNAi of mutant huntingtin expression is neuroprotective in a novel genetic rat model of Huntington's disease NR Franich, HL Fitzsimons, DM Fong, M Klugmann, MJ During, D Young Molecular Therapy 16 (5), 947-956, 2008 | 194 | 2008 |
| AAV-mediated gene delivery of BDNF or GDNF is neuroprotective in a model of Huntington disease AP Kells, DM Fong, M Dragunow, MJ During, D Young, B Connor Molecular Therapy 9 (5), 682-688, 2004 | 191 | 2004 |
| Status epilepticus may be caused by loss of adenosine anticonvulsant mechanisms D Young, M Dragunow Neuroscience 58 (2), 245-261, 1994 | 184 | 1994 |
| Efficient gene delivery and selective transduction of glial cells in the mammalian brain by AAV serotypes isolated from nonhuman primates PA Lawlor, RJ Bland, A Mouravlev, D Young, MJ During Molecular therapy 17 (10), 1692-1702, 2009 | 180 | 2009 |
| Bax expression in mammalian neurons undergoing apoptosis, and in Alzheimer's disease hippocampus GA MacGibbon, PA Lawlor, ES Sirimanne, MR Walton, B Connor, ... Brain research 750 (1-2), 223-234, 1997 | 177 | 1997 |
| Trk receptor alterations in Alzheimer's disease B Connor, D Young, P Lawlor, W Gai, H Waldvogel, RLM Faull, ... Molecular brain research 42 (1), 1-17, 1996 | 129 | 1996 |
| Recombinant AAV‐mediated expression of galanin in rat hippocampus suppresses seizure development EJD Lin, C Richichi, D Young, K Baer, A Vezzani, MJ During European Journal of Neuroscience 18 (7), 2087-2092, 2003 | 122 | 2003 |
| Development and optimization of adeno-associated virus vector transfer into the central nervous system MJ During, D Young, K Baer, P Lawlor, M Klugmann Viral vectors for gene therapy: methods and protocols, 221-236, 2003 | 114 | 2003 |
| Novel rat Alzheimer's disease models based on AAV-mediated gene transfer to selectively increase hippocampal Aβ levels PA Lawlor, RJ Bland, P Das, RW Price, V Holloway, L Smithson, ... Molecular neurodegeneration 2, 1-13, 2007 | 96 | 2007 |
