Engineered control of enzyme structural dynamics and function DD Boehr, RN D'Amico, KF O'Rourke Protein Science 27 (4), 825-838, 2018 | 43 | 2018 |
Engineering Allostery into Proteins SD Gorman, RN D’Amico, DS Winston, DD Boehr Protein Allostery in Drug Discovery, 359-384, 2019 | 14 | 2019 |
Coordinated Network Changes across the Catalytic Cycle of Alpha Tryptophan Synthase KF O'Rourke, D Sahu, YK Bosken, RN D'Amico, AC Chia-en, DD Boehr Structure 27 (9), 1405-1415. e5, 2019 | 12 | 2019 |
Substitution of a Surface-Exposed Residue Involved in an Allosteric Network Enhances Tryptophan Synthase Function in Cells RN D’Amico, YK Bosken, KF O’Rourke, AM Murray, W Admasu, ... Frontiers in molecular biosciences 8, 479, 2021 | 9 | 2021 |
Distinct conformational dynamics and allosteric networks in alpha tryptophan synthase during active catalysis KF O'Rourke, RN D'Amico, D Sahu, DD Boehr Protein Science 30 (3), 543-557, 2021 | 6 | 2021 |
Millisecond timescale motions connect amino acid interaction networks in alpha tryptophan synthase KF O'Rourke, JM Axe, RN D'Amico, D Sahu, DD Boehr Frontiers in Molecular Biosciences, 92, 2018 | 6 | 2018 |
Allostery, engineering and inhibition of tryptophan synthase RN D'Amico, DD Boehr Current Opinion in Structural Biology 82, 102657, 2023 | 2 | 2023 |
Driving Protein Conformational Cycles in Physiology and Disease:“Frustrated” Amino Acid Interaction Networks Define Dynamic Energy Landscapes: Amino Acid Interaction Networks … RN D'Amico, AM Murray, DD Boehr BioEssays 42 (9), 2000092, 2020 | 2 | 2020 |
Engineering Allostery in Tryptophan Synthase R D'Amico Pennsylvania State University, 2021 | | 2021 |