Proteolytic inactivation of MAP-kinase-kinase by anthrax lethal factor NS Duesbery, CP Webb, SH Leppla, VM Gordon, KR Klimpel, ... Science 280 (5364), 734-737, 1998 | 1294 | 1998 |
Inhibition of MAPK kinase signaling pathways suppressed renal cell carcinoma growth and angiogenesis in vivo D Huang, Y Ding, WM Luo, S Bender, CN Qian, E Kort, ZF Zhang, ... Cancer research 68 (1), 81-88, 2008 | 267 | 2008 |
Apoptosis and melanogenesis in human melanoma cells induced by anthrax lethal factor inactivation of mitogen-activated protein kinase kinase HM Koo, M VanBrocklin, MJ McWilliams, SH Leppla, NS Duesbery, ... Proceedings of the National Academy of Sciences 99 (5), 3052-3057, 2002 | 191 | 2002 |
Anthrax lethal factor proteolysis and inactivation of MAPK kinase AP Chopra, SA Boone, X Liang, NS Duesbery Journal of Biological Chemistry 278 (11), 9402-9406, 2003 | 174 | 2003 |
Suppression of ras-mediated transformation and inhibition of tumor growth and angiogenesis by anthrax lethal factor, a proteolytic inhibitor of multiple MEK pathways NS Duesbery, J Resau, CP Webb, S Koochekpour, HM Koo, SH Leppla, ... Proceedings of the National Academy of Sciences 98 (7), 4089-4094, 2001 | 146 | 2001 |
Anthrax toxins NS Duesbery, GF Vande Woude Cellular and Molecular Life Sciences CMLS 55, 1599-1609, 1999 | 114 | 1999 |
BRAF status and mitogen-activated protein/extracellular signal-regulated kinase kinase 1/2 activity indicate sensitivity of melanoma cells to anthrax lethal toxin RJ Abi-Habib, JO Urieto, S Liu, SH Leppla, NS Duesbery, AE Frankel Molecular Cancer Therapeutics 4 (9), 1303-1310, 2005 | 95 | 2005 |
MEK genomics in development and disease JL Bromberg-White, NJ Andersen, NS Duesbery Briefings in functional genomics 11 (4), 300-310, 2012 | 94 | 2012 |
Sensitizing anthrax lethal toxin-resistant macrophages to lethal toxin-induced killing by tumor necrosis factor-α SO Kim, Q Jing, K Hoebe, B Beutler, NS Duesbery, J Han Journal of Biological Chemistry 278 (9), 7413-7421, 2003 | 89 | 2003 |
Identification of VEGF-independent cytokines in proliferative diabetic retinopathy vitreous JL Bromberg-White, L Glazer, R Downer, K Furge, E Boguslawski, ... Investigative ophthalmology & visual science 54 (10), 6472-6480, 2013 | 77 | 2013 |
Anthrax lethal factor causes proteolytic inactivation of mitogen‐activated protein kinase kinase NS Duesbery, GFV Woude Journal of applied microbiology 87 (2), 289-293, 1999 | 67 | 1999 |
Anthrax toxin-induced shock in rats is associated with pulmonary edema and hemorrhage SR Kuo, MC Willingham, SH Bour, EA Andreas, SK Park, C Jackson, ... Microbial pathogenesis 44 (6), 467-472, 2008 | 65 | 2008 |
MEK wars, a new front in the battle against cancer NS Duesbery, CP Webb, GF Vande Woude Nature medicine 5 (7), 736-737, 1999 | 64 | 1999 |
Somatic inactivating PTPRJ mutations and dysregulated pathways identified in canine malignant melanoma by integrated comparative genomic analysis WPD Hendricks, V Zismann, K Sivaprakasam, C Legendre, K Poorman, ... PLoS genetics 14 (9), e1007589, 2018 | 61 | 2018 |
Xp38γ/SAPK3 promotes meiotic G2/M transition in Xenopus oocytes and activates Cdc25C E Perdiguero, MJ Pillaire, JF Bodart, F Hennersdorf, M Frödin, ... The EMBO journal, 2003 | 59 | 2003 |
Systemic anthrax lethal toxin therapy produces regressions of subcutaneous human melanoma tumors in athymic nude mice RJ Abi-Habib, R Singh, SH Leppla, JJ Greene, Y Ding, B Berghuis, ... Clinical cancer research 12 (24), 7437-7443, 2006 | 57 | 2006 |
Mitogen-activated protein kinase kinase signaling promotes growth and vascularization of fibrosarcoma Y Ding, EA Boguslawski, BD Berghuis, JJ Young, Z Zhang, K Hardy, ... Molecular cancer therapeutics 7 (3), 648-658, 2008 | 53 | 2008 |
LRP5 and LRP6 Are Not Required for Protective Antigen–Mediated Internalization or Lethality of Anthrax Lethal Toxin JJ Young, JL Bromberg-White, C Zylstra, JT Church, E Boguslawski, ... PLoS pathogens 3 (3), e27, 2007 | 53 | 2007 |
Pathophysiology of anthrax AE Frankel, SR Kuo, D Dostal, L Watson, NS Duesbery, CP Cheng, ... Frontiers in bioscience (Landmark edition) 14, 4516, 2009 | 50 | 2009 |
Anthrax, MEK and cancer JF Bodart, A Chopra, X Liang, N Duesbery Cell Cycle 1 (1), 7-12, 2002 | 46 | 2002 |