Easily accessible polycyclic amines that inhibit the wild-type and amantadine-resistant mutants of the M2 channel of influenza A virus M Rey-Carrizo, M Barniol-Xicota, C Ma, M Frigolé-Vivas, E Torres, ... Journal of medicinal chemistry 57 (13), 5738-5747, 2014 | 64 | 2014 |
3-Azatetracyclo[5.2.1.15,8.01,5]undecane Derivatives: From Wild-Type Inhibitors of the M2 Ion Channel of Influenza A Virus to Derivatives with Potent Activity … M Rey-Carrizo, E Torres, C Ma, M Barniol-Xicota, J Wang, Y Wu, ... Journal of medicinal chemistry 56 (22), 9265-9274, 2013 | 55 | 2013 |
Stable and functional rhomboid proteases in lipid nanodiscs by using diisobutylene/maleic acid copolymers M Barniol-Xicota, SHL Verhelst Journal of the American Chemical Society 140 (44), 14557-14561, 2018 | 51 | 2018 |
3D‐Printed Polypropylene Continuous‐Flow Column Reactors: Exploration of Reactor Utility in SNAr Reactions and the Synthesis of Bicyclic and Tetracyclic … ZX Rao, B Patel, A Monaco, ZJ Cao, M Barniol‐Xicota, E Pichon, ... European Journal of Organic Chemistry 2017 (44), 6499-6504, 2017 | 51 | 2017 |
Heme-regulated eIF2α kinase modulates hepatic FGF21 and is activated by PPARβ/δ deficiency M Zarei, E Barroso, R Leiva, M Barniol-Xicota, E Pujol, C Escolano, ... Diabetes 65 (10), 3185-3199, 2016 | 42 | 2016 |
A novel class of multitarget anti-Alzheimer benzohomoadamantane‒chlorotacrine hybrids modulating cholinesterases and glutamate NMDA receptors FJ Pérez-Areales, AL Turcu, M Barniol-Xicota, C Pont, D Pivetta, ... European Journal of Medicinal Chemistry 180, 613-626, 2019 | 40 | 2019 |
Aniline-based inhibitors of influenza H1N1 virus acting on hemagglutinin-mediated fusion R Leiva, M Barniol-Xicota, S Codony, T Ginex, E Vanderlinden, M Montes, ... Journal of medicinal chemistry 61 (1), 98-118, 2018 | 40 | 2018 |
Peptidyl Acyloxymethyl Ketones as Activity‐Based Probes for the Main Protease of SARS‐CoV‐2 MAT van de Plassche, M Barniol‐Xicota, SHL Verhelst ChemBioChem 21 (23), 3383-3388, 2020 | 34 | 2020 |
Discovery of cellular roles of intramembrane proteases HA Beard, M Barniol-Xicota, J Yang, SHL Verhelst ACS Chemical Biology 14 (11), 2372-2388, 2019 | 24 | 2019 |
Short Total Synthesis of (±)‐γ‐Lycorane by a Sequential Intramolecular Acylal Cyclisation (IAC) and Intramolecular Heck Addition Reaction A Monaco, BR Szulc, ZX Rao, M Barniol‐Xicota, M Sehailia, BMA Borges, ... Chemistry–A European Journal 23 (20), 4750-4755, 2017 | 23 | 2017 |
Lipidomic and in-gel analysis of maleic acid co-polymer nanodiscs reveals differences in composition of solubilized membranes M Barniol-Xicota, SHL Verhelst Communications Biology 4 (1), 218, 2021 | 22 | 2021 |
Slow but steady wins the race: dissimilarities among new dual inhibitors of the wild-type and the V27A mutant M2 channels of influenza A virus M Barniol-Xicota, S Gazzarrini, E Torres, Y Hu, J Wang, L Naesens, ... Journal of medicinal chemistry 60 (9), 3727-3738, 2017 | 22 | 2017 |
Syntheses of cinacalcet: an enantiopure active pharmaceutical ingredient (API) M Barniol-Xicota, R Leiva, C Escolano, S Vázquez Synthesis 48 (06), 783-803, 2016 | 22 | 2016 |
Towards a novel class of multitarget-directed ligands: dual P2X7–NMDA receptor antagonists O Karoutzou, SH Kwak, SD Lee, D Martínez-Falguera, FX Sureda, ... Molecules 23 (1), 230, 2018 | 21 | 2018 |
Benzoxazin-4-ones as novel, easily accessible inhibitors for rhomboid proteases J Yang, M Barniol-Xicota, MTN Nguyen, A Ticha, K Strisovsky, ... Bioorganic & Medicinal Chemistry Letters 28 (8), 1423-1427, 2018 | 20 | 2018 |
Inhibitors of the M2 channel of influenza A virus MD Duque, E Torres Costa, E Valverde Murillo, M Barniol-Xicota, ... Recent Advances in Pharmaceutical Sciences, 2011, Chapter 2, p. 35-64 …, 2011 | 18 | 2011 |
Escape from adamantane: scaffold optimization of novel P2X7 antagonists featuring complex polycycles M Barniol-Xicota, SH Kwak, SD Lee, E Caseley, E Valverde, LH Jiang, ... Bioorganic & Medicinal Chemistry Letters 27 (4), 759-763, 2017 | 12 | 2017 |
Activation pH and Gating Dynamics of Influenza A M2 Proton Channel Revealed by Single‐Molecule Spectroscopy CW Lin, B Mensa, M Barniol‐Xicota, WF DeGrado, F Gai Angewandte Chemie 129 (19), 5367-5371, 2017 | 11 | 2017 |
A Free-Radical and Protecting-Group-Free Approach to (–)-Boschnialactone and γ-Lycorane A Basante-Avendaño, VE Guerra-Ayala, A Sánchez-Eleuterio, ... Synthesis 51 (10), 2207-2213, 2019 | 9 | 2019 |
Dimerization of Pyramidalized 3,4,8,9‐Tetramethyltetracyclo [4.4.0.03,9.04,8]dec‐1(6)‐ene to a Hydrocarbon Featuring Four Cyclohexane Rings in Boat … M Rey‐Carrizo, M Barniol‐Xicota, M Font‐Bardia, S Vázquez Angewandte Chemie International Edition 53 (31), 8195-8199, 2014 | 9 | 2014 |