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Kira Astakhova
Kira Astakhova
Danmarks Tekniske Universitet
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Lipid nanoparticles for delivery of therapeutic RNA oligonucleotides
KH Moss, P Popova, SR Hadrup, K Astakhova, M Taskova
Molecular pharmaceutics 16 (6), 2265-2277, 2019
832019
Highly Fluorescent Conjugated Pyrenes in Nucleic Acid Probes:(Phenylethynyl) pyrenecarbonyl‐Functionalized Locked Nucleic Acids
IV Astakhova, VA Korshun, J Wengel
Chemistry–A European Journal 14 (35), 11010-11026, 2008
712008
Scaffolding along nucleic acid duplexes using 2′-amino-locked nucleic acids
IK Astakhova, J Wengel
Accounts of chemical research 47 (6), 1768-1777, 2014
702014
1‐, 2‐, and 4‐Ethynylpyrenes in the Structure of Twisted Intercalating Nucleic Acids: Structure, Thermal Stability, and Fluorescence Relationship
VV Filichev, IV Astakhova, AD Malakhov, VA Korshun, EB Pedersen
Chemistry–A European Journal 14 (32), 9968-9980, 2008
692008
Interfacing click chemistry with automated oligonucleotide synthesis for the preparation of fluorescent DNA probes containing internal xanthene and cyanine dyes
IK Astakhova, J Wengel
Chemistry–A European Journal 19 (3), 1112-1122, 2013
572013
Pyrene–perylene as a FRET pair coupled to the N2′-functionality of 2′-amino-LNA
D Lindegaard, AS Madsen, IV Astakhova, AD Malakhov, BR Babu, ...
Bioorganic & medicinal chemistry 16 (1), 94-99, 2008
572008
Perylene Attached to 2′-Amino-LNA: Synthesis, Incorporation into Oligonucleotides, and Remarkable Fluorescence Properties in Vitro and in Cell Culture
IV Astakhova, VA Korshun, K Jahn, J Kjems, J Wengel
Bioconjugate chemistry 19 (10), 1995-2007, 2008
552008
Sensitive SNP Dual‐Probe Assays Based on Pyrene‐Functionalized 2′‐Amino‐LNA: Lessons To Be Learned
T Umemoto, PJ Hrdlicka, BR Babu, J Wengel
ChemBioChem 8 (18), 2240-2248, 2007
472007
1-Phenylethynylpyrene (1-PEPy) as refined excimer forming alternative to pyrene: Case of DNA major groove excimer
IV Astakhova, AD Malakhov, IA Stepanova, AV Ustinov, SL Bondarev, ...
Bioconjugate chemistry 18 (6), 1972-1980, 2007
462007
Autoantibodies in morphea: an update
S Khatri, KS Torok, E Mirizio, C Liu, K Astakhova
Frontiers in immunology 10, 462707, 2019
402019
Antisense oligonucleotides internally labeled with peptides show improved target recognition and stability to enzymatic degradation
M Taskova, CS Madsen, KJ Jensen, LH Hansen, B Vester, K Astakhova
Bioconjugate chemistry 28 (3), 768-774, 2017
342017
Peptide–LNA oligonucleotide conjugates
IK Astakhova, LH Hansen, B Vester, J Wengel
Organic & Biomolecular Chemistry 11 (25), 4240-4249, 2013
342013
Novel interstrand communication systems within DNA duplexes based on 1-, 2-and 4-(phenylethynyl) pyrenes attached to 2′-amino-LNA: high-affinity hybridization and fluorescence …
IV Astakhova, D Lindegaard, VA Korshun, J Wengel
Chemical communications 46 (44), 8362-8364, 2010
342010
Synthetic nucleic acid analogues in gene therapy: an update for peptide–oligonucleotide conjugates
M Taskova, A Mantsiou, K Astakhova
ChemBioChem 18 (17), 1671-1682, 2017
322017
Novel (phenylethynyl) pyrene–LNA constructs for fluorescence SNP sensing in polymorphic nucleic acid targets
IK Astakhova, E Samokhina, BR Babu, J Wengel
ChemBioChem 13 (10), 1509-1519, 2012
302012
Branched DNA nanostructures efficiently stabilised and monitored by novel pyrene–perylene 2′-α-l-amino-LNA FRET pairs
IK Astakhova, TS Kumar, MA Campbell, AV Ustinov, VA Korshun, ...
Chemical communications 49 (5), 511-513, 2013
292013
Reactive trityl derivatives: stabilised carbocation mass-tags for life sciences applications
AV Ustinov, VV Shmanai, K Patel, IA Stepanova, IA Prokhorenko, ...
Organic & Biomolecular Chemistry 6 (24), 4593-4608, 2008
292008
Carbon nanotubes—potent carriers for targeted drug delivery in rheumatoid arthritis
C Kofoed Andersen, S Khatri, J Hansen, S Slott, R Pavan Parvathaneni, ...
Pharmaceutics 13 (4), 453, 2021
272021
LNA for optimization of fluorescent oligonucleotide probes: improved spectral properties and target binding
IV Astakhova, AV Ustinov, VA Korshun, J Wengel
Bioconjugate Chemistry 22 (4), 533-539, 2011
272011
Revealing nucleic acid mutations using Förster resonance energy transfer-based probes
NPL Junager, J Kongsted, K Astakhova
Sensors 16 (8), 1173, 2016
262016
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