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Sarah Gourmaud
Sarah Gourmaud
Perelman School of Medicine, University of Pennsylvania
Adresse e-mail validée de pennmedicine.upenn.edu
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Neurofilament markers for ALS correlate with extent of upper and lower motor neuron disease
K Poesen, M De Schaepdryver, B Stubendorff, B Gille, P Muckova, ...
Neurology 88 (24), 2302-2309, 2017
2062017
Mapping the navigational knowledge of individually foraging ants, Myrmecia croslandi
A Narendra, S Gourmaud, J Zeil
Proceedings of the Royal Society B: Biological Sciences 280 (1765), 20130683, 2013
1472013
Increased levels of cerebrospinal fluid JNK3 associated with amyloid pathology: links to cognitive decline
S Gourmaud, C Paquet, J Dumurgier, C Pace, C Bouras, F Gray, ...
Journal of Psychiatry and Neuroscience 40 (3), 151-161, 2015
1012015
Neuroinflammation and Aβ accumulation linked to systemic inflammation are decreased by genetic PKR down-regulation
AS Carret-Rebillat, C Pace, S Gourmaud, L Ravasi, S Montagne-Stora, ...
Scientific Reports 5 (1), 8489, 2015
962015
Alzheimer-like amyloid and tau alterations associated with cognitive deficit in temporal lobe epilepsy
S Gourmaud, H Shou, DJ Irwin, K Sansalone, LM Jacobs, TH Lucas, ...
Brain 143 (1), 191-209, 2020
912020
Mechanistic target of rapamycin complex 1 and 2 in human temporal lobe epilepsy
DM Talos, LM Jacobs, S Gourmaud, CA Coto, H Sun, KC Lim, TH Lucas, ...
Annals of neurology 83 (2), 311-327, 2018
742018
PKR downregulation prevents neurodegeneration and β-amyloid production in a thiamine-deficient model
F Mouton-Liger, AS Rebillat, S Gourmaud, C Paquet, A Leguen, ...
Cell death & disease 6 (1), e1594-e1594, 2015
452015
PKR knockout in the 5xFAD model of Alzheimer's disease reveals beneficial effects on spatial memory and brain lesions
M Tible, F Mouton Liger, J Schmitt, A Giralt, K Farid, S Thomasseau, ...
Aging Cell 18 (3), e12887, 2019
342019
The role of mTORC1 activation in seizure-induced exacerbation of Alzheimer's disease
S Gourmaud, DA Stewart, DJ Irwin, N Roberts, AJ Barbour, G Eberwine, ...
Brain 145 (1), 324-339, 2022
192022
PKR modulates abnormal brain signaling in experimental obesity
M Taga, F Mouton-Liger, M Sadoune, S Gourmaud, J Norman, M Tible, ...
PLoS One 13 (5), e0196983, 2018
152018
Brimapitide reduced neuronal stress markers and cognitive deficits in 5XFAD transgenic mice
S Gourmaud, P Thomas, S Thomasseau, M Tible, C Abadie, C Paquet, ...
Journal of Alzheimer's Disease 63 (2), 665-674, 2018
132018
Dual kinase inhibition affords extended in vitro neuroprotection in amyloid-β toxicity
S Gourmaud, F Mouton-Liger, C Abadie, EF Meurs, C Paquet, J Hugon
Journal of Alzheimer's Disease 54 (4), 1659-1670, 2016
112016
Effect of anti-cancer drugs on microglia in patient-derived breast cancer xenografted mouse models
C Paquet, D Boche, M El Bouchtaoui, S Gourmaud, A Janin, G Bousquet
Neuropathology, 1-3, 2017
52017
Excitatory: inhibitory imbalance in Alzheimer’s disease is exacerbated by seizures with attenuation after rapamycin treatment in 5XFAD mice
AJ Barbour, S Gourmaud, E Lancaster, X Li, D Stewart, DJ Irwin, ...
bioRxiv, 2023.03. 02.530499, 2023
22023
Optical Redox Imaging of Ex Vivo Hippocampal Tissue Reveals Age-Dependent Alterations in the 5XFAD Mouse Model of Alzheimer’s Disease
HN Xu, S Gourmaud, A Podsednik, X Li, H Zhao, FE Jensen, DM Talos, ...
Metabolites 12 (9), 786, 2022
22022
Seizures exacerbate excitatory: inhibitory imbalance in Alzheimer’s disease and 5XFAD mice
AJ Barbour, S Gourmaud, E Lancaster, X Li, DA Stewart, KF Hoag, ...
Brain, awae126, 2024
2024
Seizures exacerbate excitatory‐inhibitory imbalance and tau seeding effects in 5XFAD mice
AJ Barbour, S Gourmaud, DA Stewart, X Li, SE Zebrowitz, S Ferrigno, ...
Alzheimer's & Dementia 19, e067907, 2023
2023
Seizures Enhance Excitatory-Inhibitory Imbalance in 5XFAD Mice and Exacerbate Tau Spread
AJ Barbour, S Gourmaud, D Stewart, X Li, S Zebrowitz, S Ferrigno, ...
ANNALS OF NEUROLOGY 92, S163-S163, 2022
2022
History of Seizures in Alzheimer's Disease Patients is Associated with Elevations in mTOR Activity and Neuropathology
DA Stewart, S Gourmaud, DJ Irwin, DM Talos, FE Jensen
ANNALS OF NEUROLOGY 88, S98-S99, 2020
2020
Exacerbation of Alzheimer’s Disease Neuropathology and Cognitive Deficits by Seizures (4120)
S Gourmaud, D Stewart, D Talos, F Jensen
Neurology 94 (15 Supplement), 2020
2020
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