Tom N. Grossmann

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Citations	6155	3564
h-index	37	30
i10-index	67	58

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Oliver SeitzProfessor für Bioorganische Synthese, Humboldt University BerlinVerified email at chemie.hu-berlin.de
Gregory VerdineProfessor of Stem Cell and Regenerative Biology, Harvard UniversityVerified email at harvard.edu
Herbert WaldmannMax-Planck-Institut DortmundVerified email at mpi-dortmund.mpg.de
Sven HennigAssociate Professor Vrije Universiteit AmsterdamVerified email at vu.nl
Christian OttmannEindhoven University of TechnologyVerified email at tue.nl
Christoph RademacherProfessor for Molecular Drug Targeting, University of Vienna, Department of Pharmaceutical SciencesVerified email at univie.ac.at
Qian ChuSalk Institute for Biological StudiesVerified email at salk.edu
Roger GoodyProfessor Max-Planck-Institute, DortmundVerified email at mpi-dortmund.mpg.de
Paolo GriecoUniversity of Naples Federico IIVerified email at unina.it
Luc BrunsveldHoogleraar Chemische Biologie, TU EindhovenVerified email at tue.nl
Alan GerberAssistant Professor, Amsterdam UMC, Location VUmcVerified email at amsterdamumc.nl
Manuel EtzkornPhysical Biology - University of DuesseldorfVerified email at uni-duesseldorf.de
Aymelt ItzenProfessor of Biochemistry, University Medical Center Hamburg-Eppendorf (UKE)Verified email at uke.de
Nicholas M PearceAssistant Professor, Linköping UniversityVerified email at liu.se
Prof. Dr. Nico DissmeyerUniversity of Osnabruck, Dept. of Plant PhysiologyVerified email at uni-osnabrueck.de
Mark D. WhiteARC DECRA Fellow, University of SydneyVerified email at sydney.edu.au
Jessica BertrandVerified email at med.ovgu.de
Wilbert BitterVU university & VU university medical centerVerified email at vumc.nl
Ettore NovellinoDipartimento di Farmacia, Università degli Studi di Napoli Federico IIVerified email at unina.it
Diego BrancaccioDipartimento di Farmacia - Universita' degli studi di Napoli, Federico IIVerified email at unina.it

Tom N. Grossmann

Professor of Biomimetic Chemistry, Vrije Universiteit Amsterdam

Verified email at vu.nl - Homepage

Chemical Biology Peptidomimetics Proteomimetics Chemical Protein Engineering


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Structure‐based design of inhibitors of protein–protein interactions: mimicking peptide binding epitopes M Pelay‐Gimeno, A Glas, O Koch, TN Grossmann Angewandte Chemie International Edition 54 (31), 8896-8927, 2015	679	2015
Modulators of protein–protein interactions LG Milroy, TN Grossmann, S Hennig, L Brunsveld, C Ottmann Chemical reviews 114 (9), 4695-4748, 2014	485	2014
Synthesis of all-hydrocarbon stapled α-helical peptides by ring-closing olefin metathesis YW Kim, TN Grossmann, GL Verdine Nature protocols 6 (6), 761-771, 2011	423	2011
New modalities for challenging targets in drug discovery E Valeur, SM Guéret, H Adihou, R Gopalakrishnan, M Lemurell, ... Angewandte Chemie International Edition 56 (35), 10294-10323, 2017	338	2017
Hydrocarbon stapled peptides as modulators of biological function PM Cromm, J Spiegel, TN Grossmann ACS chemical biology 10 (6), 1362-1375, 2015	288	2015
Inhibition of oncogenic Wnt signaling through direct targeting of β-catenin TN Grossmann, JTH Yeh, BR Bowman, Q Chu, RE Moellering, ... Proceedings of the National Academy of Sciences 109 (44), 17942-17947, 2012	278	2012
Small-molecule modulation of Ras signaling J Spiegel, PM Cromm, G Zimmermann, TN Grossmann, H Waldmann Nature chemical biology 10 (8), 613-622, 2014	263	2014
Towards understanding cell penetration by stapled peptides Q Chu, RE Moellering, GJ Hilinski, YW Kim, TN Grossmann, JTH Yeh, ... MedChemComm 6 (1), 111-119, 2015	255	2015
Plant cysteine oxidases are dioxygenases that directly enable arginyl transferase-catalysed arginylation of N-end rule targets MD White, M Klecker, RJ Hopkinson, DA Weits, C Mueller, C Naumann, ... Nature communications 8 (1), 14690, 2017	180	2017
DNA-catalyzed transfer of a reporter group TN Grossmann, O Seitz Journal of the American Chemical Society 128 (49), 15596-15597, 2006	159	2006
Constrained peptides with target‐adapted cross‐links as inhibitors of a pathogenic protein–protein interaction A Glas, D Bier, G Hahne, C Rademacher, C Ottmann, TN Grossmann Angewandte Chemie International Edition 53 (9), 2489-2493, 2014	145	2014
Triplex molecular beacons as modular probes for DNA detection TN Grossmann, L Röglin, O Seitz Angewandte Chemie International Edition 46 (27), 5223-5225, 2007	144	2007
Achieving turnover in DNA‐templated reactions TN Grossmann, A Strohbach, O Seitz ChemBioChem 9 (14), 2185-2192, 2008	132	2008
Bifunctional stapled polypeptides and uses thereof GL Verdine, TN Grossmann, RE Moellering, THJ Yeh, YRY Liang, Y Oak US Patent 9,163,330, 2015	129	2015
Cell permeable stapled peptide inhibitor of Wnt signaling that targets β-catenin protein-protein interactions L Dietrich, B Rathmer, K Ewan, T Bange, S Heinrichs, TC Dale, D Schade, ... Cell chemical biology 24 (8), 958-968. e5, 2017	116	2017
Direct Targeting of Rab‐GTPase–Effector Interactions J Spiegel, PM Cromm, A Itzen, RS Goody, TN Grossmann, H Waldmann Angewandte Chemie International Edition 53 (9), 2498-2503, 2014	103	2014
Proteomimetics as protein-inspired scaffolds with defined tertiary folding patterns WS Horne, TN Grossmann Nature chemistry 12 (4), 331-337, 2020	102	2020
Orthogonal ring-closing alkyne and olefin metathesis for the synthesis of small GTPase-targeting bicyclic peptides PM Cromm, S Schaubach, J Spiegel, A Fürstner, TN Grossmann, ... Nature communications 7 (1), 11300, 2016	100	2016
Nucleic acid templated reactions: consequences of probe reactivity and readout strategy for amplified signaling and sequence selectivity TN Grossmann, O Seitz Chemistry–A European Journal 15 (27), 6723-6730, 2009	87	2009
Direct modulation of small GTPase activity and function PM Cromm, J Spiegel, TN Grossmann, H Waldmann Angewandte Chemie International Edition 54 (46), 13516-13537, 2015	83	2015

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