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Meghana Pagadala
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Osteoclast activated FoxP3+ CD8+ T-cells suppress bone resorption in vitro
ZS Buchwald, JR Kiesel, R DiPaolo, MS Pagadala, R Aurora
PloS one 7 (6), e38199, 2012
852012
Domain-swapped T cell receptors improve the safety of TCR gene therapy
MT Bethune, MH Gee, M Bunse, MS Lee, EH Gschweng, MS Pagadala, ...
Elife 5, e19095, 2016
572016
Germline and somatic genetic variants in the p53 pathway interact to affect cancer risk, progression, and drug response
P Zhang, I Kitchen-Smith, L Xiong, G Stracquadanio, K Brown, PH Richter, ...
Cancer research 81 (7), 1667-1680, 2021
402021
Polygenic risk of any, metastatic, and fatal prostate cancer in the Million Veteran Program
MS Pagadala, J Lynch, R Karunamuni, PR Alba, KM Lee, FY Agiri, ...
JNCI: Journal of the National Cancer Institute 115 (2), 190-199, 2023
132023
The role of testosterone, the androgen receptor, and hypothalamic-pituitary–gonadal axis in depression in ageing Men
RL Hauger, UG Saelzler, MS Pagadala, MS Panizzon
Reviews in Endocrine and Metabolic Disorders 23 (6), 1259-1273, 2022
112022
A common polymorphism in the retinoic acid pathway modifies adrenocortical carcinoma age-dependent incidence
M Surakhy, M Wallace, E Bond, LF Grochola, H Perez, ...
British journal of cancer 122 (8), 1231-1241, 2020
112020
The GPCR–Gαs–PKA signaling axis promotes T cell dysfunction and cancer immunotherapy failure
VH Wu, BS Yung, F Faraji, R Saddawi-Konefka, Z Wang, AT Wenzel, ...
Nature immunology 24 (8), 1318-1330, 2023
102023
The landscape of extrachromosomal circular DNA in medulloblastoma
OS Chapman, J Luebeck, S Wani, A Tiwari, M Pagadala, S Wang, ...
bioRxiv, 2021.10. 18.464907, 2021
102021
Germline modifiers of the tumor immune microenvironment implicate drivers of cancer risk and immunotherapy response
M Pagadala, TJ Sears, VH Wu, E Pérez-Guijarro, H Kim, A Castro, ...
Nature communications 14 (1), 2744, 2023
82023
Cell contractility drives mechanical memory of oral squamous cell carcinoma
SY Moon, PS de Campos, BF Matte, JK Placone, VG Zanella, MD Martins, ...
Molecular Biology of the Cell 34 (9), ar89, 2023
42023
Healthy lifestyle and prostate cancer risk in the Million Veteran Program
MS Pagadala, A Lui, J Lynch, R Karunamuni, KM Lee, A Plym, BS Rose, ...
medRxiv, 2022.07. 09.22277437, 2022
32022
Non-cancer-related pathogenic germline variants and expression consequences in ten-thousand cancer genomes
Z Wang, X Fan, Y Shen, MS Pagadala, R Signer, KJ Cygan, ...
Genome medicine 13, 1-13, 2021
32021
Evaluating a polygenic hazard score to predict risk of developing metastatic or fatal prostate cancer in the multi-ancestry Million Veteran Program cohort
MS Pagadala, J Lynch, R Karunamuni, PR Alba, KM Lee, FY Agiri, ...
medRxiv, 2021.09. 24.21264093, 2021
32021
Circular extrachromosomal DNA promotes tumor heterogeneity in high-risk medulloblastoma
OS Chapman, J Luebeck, S Sridhar, ITL Wong, D Dixit, S Wang, G Prasad, ...
Nature genetics 55 (12), 2189-2199, 2023
22023
3D genome mapping identifies subgroup-specific chromosome conformations and tumor-dependency genes in ependymoma
K Okonechnikov, A Camgöz, O Chapman, S Wani, DE Park, JM Hübner, ...
Nature Communications 14 (1), 2300, 2023
22023
Accurate genome-wide genotyping from archival tissue to explore the contribution of common genetic variants to pre-cancer outcomes
D Nachmanson, M Pagadala, J Steward, C Cheung, LK Bruce, NQ Lee, ...
Journal of Translational Medicine 20 (1), 623, 2022
22022
PRState: Incorporating genetic ancestry in prostate cancer risk scores for men of African ancestry
MS Pagadala, JA Linscott, JV Talwar, TM Seibert, B Rose, J Lynch, ...
BMC cancer 22 (1), 1289, 2022
22022
Germline variants that influence the tumor immune microenvironment also drive response to immunotherapy
M Pagadala, VH Wu, E Pérez-Guijarro, H Kim, A Castro, J Talwar, ...
BioRxiv, 2021
22021
Adrenal-Permissive Germline HSD3B1 Allele and Prostate Cancer Outcomes
RR McKay, TJ Nelson, MS Pagadala, CC Teerlink, A Gao, AK Bryant, ...
JAMA Network Open 7 (3), e242976-e242976, 2024
12024
Genetic risk and likelihood of prostate cancer detection on first biopsy by ancestry
KM Lee, TJ Nelson, A Bryant, CC Teerlink, R Gulati, MS Pagadala, ...
JNCI: Journal of the National Cancer Institute, djae002, 2024
12024
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