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Jianjun Wu
Jianjun Wu
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Year
Inhibition of cGAS DNA sensing by a herpesvirus virion protein
J Wu, W Li, Y Shao, D Avey, B Fu, J Gillen, T Hand, S Ma, X Liu, W Miley, ...
Cell host & microbe 18 (3), 333-344, 2015
2582015
Trafficking-mediated STING degradation requires sorting to acidified endolysosomes and can be targeted to enhance anti-tumor response
VK Gonugunta, T Sakai, V Pokatayev, K Yang, J Wu, N Dobbs, N Yan
Cell reports 21 (11), 3234-3242, 2017
2302017
Interferon-independent activities of mammalian STING mediate antiviral response and tumor immune evasion
J Wu, N Dobbs, K Yang, N Yan
Immunity 53 (1), 115-126. e5, 2020
2052020
STING-mediated disruption of calcium homeostasis chronically activates ER stress and primes T cell death
J Wu, YJ Chen, N Dobbs, T Sakai, J Liou, JJ Miner, N Yan
The Journal of experimental medicine 216 (4), 867-883, 2019
2022019
STING-associated vasculopathy develops independently of IRF3 in mice
JD Warner, RA Irizarry-Caro, BG Bennion, TL Ai, AM Smith, CA Miner, ...
Journal of Experimental Medicine 214 (11), 3279-3292, 2017
1612017
Tonic prime-boost of STING signalling mediates Niemann–Pick disease type C
TT Chu, X Tu, K Yang, J Wu, JJ Repa, N Yan
Nature 596 (7873), 570-575, 2021
1212021
Homeostatic regulation of STING protein at the resting state by stabilizer TOLLIP
V Pokatayev, K Yang, X Tu, N Dobbs, J Wu, RG Kalb, N Yan
Nature immunology 21 (2), 158-167, 2020
832020
Mitochondrial GCD1 dysfunction reveals reciprocal cell-to-cell signaling during the maturation of Arabidopsis female gametes
JJ Wu, XB Peng, WW Li, R He, HP Xin, MX Sun
Developmental Cell 23 (5), 1043-1058, 2012
672012
Kaposi's sarcoma-associated herpesvirus inhibitor of cGAS (KicGAS), encoded by ORF52, is an abundant tegument protein and is required for production of infectious progeny viruses
W Li, D Avey, B Fu, J Wu, S Ma, X Liu, F Zhu
Journal of virology 90 (11), 5329-5342, 2016
542016
A survey of the interactome of Kaposi's sarcoma-associated herpesvirus ORF45 revealed its binding to viral ORF33 and cellular USP7, resulting in stabilization of ORF33 that is …
J Gillen, W Li, Q Liang, D Avey, J Wu, F Wu, JJ Myoung, F Zhu
Journal of virology 89 (9), 4918-4931, 2015
412015
ORF33 and ORF38 of Kaposi's sarcoma-associated herpesvirus interact and are required for optimal production of infectious progeny viruses
J Wu, D Avey, W Li, J Gillen, B Fu, W Miley, D Whitby, F Zhu
Journal of virology 90 (4), 1741-1756, 2016
322016
Cooperative DNA binding mediated by KicGAS/ORF52 oligomerization allows inhibition of DNA-induced phase separation and activation of cGAS
D Bhowmik, M Du, Y Tian, S Ma, J Wu, Z Chen, Q Yin, F Zhu
Nucleic acids research 49 (16), 9389-9403, 2021
242021
No longer a one-trick pony: STING signaling activity beyond interferon
J Wu, N Yan
Journal of molecular biology 434 (6), 167257, 2022
202022
STIM1 moonlights as an anchor for STING
J Wu, N Yan
Nature immunology 20 (2), 112-114, 2019
152019
Three STIGMA AND STYLE STYLISTs pattern the fine architectures of apical gynoecium and are critical for male gametophyte-pistil interaction
W Li, X Huang, J Zou, J Wu, H Jiao, X Peng, M Sun
Current Biology 30 (23), 4780-4788. e5, 2020
62020
Mitochondria-responsive signaling between egg and central cell controls their coordinated maturation
J Wu, X Peng, M Sun
Plant signaling & behavior 8 (5), 1043-58, 2013
42013
A “KU” new sensor for cytosolic DNA in T cells
J Wu, N Yan
Immunity 54 (4), 603-605, 2021
32021
STING-mediated chronic activation of ER stress through disrupting calcium homeostasis primes T cells for cell death
J Wu, N Yan
The Journal of Immunology 202 (1_Supplement), 180.15-180.15, 2019
12019
Gain-of-function STING mutations induce T cell death in the SAVI mouse
J Wu, N Yan
The Journal of Immunology 200 (1_Supplement), 166.29-166.29, 2018
12018
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