Inhibition of cGAS DNA sensing by a herpesvirus virion protein J Wu, W Li, Y Shao, D Avey, B Fu, J Gillen, T Hand, S Ma, X Liu, W Miley, ... Cell host & microbe 18 (3), 333-344, 2015 | 258 | 2015 |
Trafficking-mediated STING degradation requires sorting to acidified endolysosomes and can be targeted to enhance anti-tumor response VK Gonugunta, T Sakai, V Pokatayev, K Yang, J Wu, N Dobbs, N Yan Cell reports 21 (11), 3234-3242, 2017 | 230 | 2017 |
Interferon-independent activities of mammalian STING mediate antiviral response and tumor immune evasion J Wu, N Dobbs, K Yang, N Yan Immunity 53 (1), 115-126. e5, 2020 | 205 | 2020 |
STING-mediated disruption of calcium homeostasis chronically activates ER stress and primes T cell death J Wu, YJ Chen, N Dobbs, T Sakai, J Liou, JJ Miner, N Yan The Journal of experimental medicine 216 (4), 867-883, 2019 | 202 | 2019 |
STING-associated vasculopathy develops independently of IRF3 in mice JD Warner, RA Irizarry-Caro, BG Bennion, TL Ai, AM Smith, CA Miner, ... Journal of Experimental Medicine 214 (11), 3279-3292, 2017 | 161 | 2017 |
Tonic prime-boost of STING signalling mediates Niemann–Pick disease type C TT Chu, X Tu, K Yang, J Wu, JJ Repa, N Yan Nature 596 (7873), 570-575, 2021 | 121 | 2021 |
Homeostatic regulation of STING protein at the resting state by stabilizer TOLLIP V Pokatayev, K Yang, X Tu, N Dobbs, J Wu, RG Kalb, N Yan Nature immunology 21 (2), 158-167, 2020 | 83 | 2020 |
Mitochondrial GCD1 dysfunction reveals reciprocal cell-to-cell signaling during the maturation of Arabidopsis female gametes JJ Wu, XB Peng, WW Li, R He, HP Xin, MX Sun Developmental Cell 23 (5), 1043-1058, 2012 | 67 | 2012 |
Kaposi's sarcoma-associated herpesvirus inhibitor of cGAS (KicGAS), encoded by ORF52, is an abundant tegument protein and is required for production of infectious progeny viruses W Li, D Avey, B Fu, J Wu, S Ma, X Liu, F Zhu Journal of virology 90 (11), 5329-5342, 2016 | 54 | 2016 |
A survey of the interactome of Kaposi's sarcoma-associated herpesvirus ORF45 revealed its binding to viral ORF33 and cellular USP7, resulting in stabilization of ORF33 that is … J Gillen, W Li, Q Liang, D Avey, J Wu, F Wu, JJ Myoung, F Zhu Journal of virology 89 (9), 4918-4931, 2015 | 41 | 2015 |
ORF33 and ORF38 of Kaposi's sarcoma-associated herpesvirus interact and are required for optimal production of infectious progeny viruses J Wu, D Avey, W Li, J Gillen, B Fu, W Miley, D Whitby, F Zhu Journal of virology 90 (4), 1741-1756, 2016 | 32 | 2016 |
Cooperative DNA binding mediated by KicGAS/ORF52 oligomerization allows inhibition of DNA-induced phase separation and activation of cGAS D Bhowmik, M Du, Y Tian, S Ma, J Wu, Z Chen, Q Yin, F Zhu Nucleic acids research 49 (16), 9389-9403, 2021 | 24 | 2021 |
No longer a one-trick pony: STING signaling activity beyond interferon J Wu, N Yan Journal of molecular biology 434 (6), 167257, 2022 | 20 | 2022 |
STIM1 moonlights as an anchor for STING J Wu, N Yan Nature immunology 20 (2), 112-114, 2019 | 15 | 2019 |
Three STIGMA AND STYLE STYLISTs pattern the fine architectures of apical gynoecium and are critical for male gametophyte-pistil interaction W Li, X Huang, J Zou, J Wu, H Jiao, X Peng, M Sun Current Biology 30 (23), 4780-4788. e5, 2020 | 6 | 2020 |
Mitochondria-responsive signaling between egg and central cell controls their coordinated maturation J Wu, X Peng, M Sun Plant signaling & behavior 8 (5), 1043-58, 2013 | 4 | 2013 |
A “KU” new sensor for cytosolic DNA in T cells J Wu, N Yan Immunity 54 (4), 603-605, 2021 | 3 | 2021 |
STING-mediated chronic activation of ER stress through disrupting calcium homeostasis primes T cells for cell death J Wu, N Yan The Journal of Immunology 202 (1_Supplement), 180.15-180.15, 2019 | 1 | 2019 |
Gain-of-function STING mutations induce T cell death in the SAVI mouse J Wu, N Yan The Journal of Immunology 200 (1_Supplement), 166.29-166.29, 2018 | 1 | 2018 |