| A functional variant of lymphoid tyrosine phosphatase is associated with type I diabetes N Bottini, L Musumeci, A Alonso, S Rahmouni, K Nika, M Rostamkhani, ... Nature genetics 36 (4), 337-338, 2004 | 1764 | 2004 |
| The transcriptional landscape of polyploid wheat RH Ramírez-González, P Borrill, D Lang, SA Harrington, J Brinton, ... Science 361 (6403), eaar6089, 2018 | 742 | 2018 |
| The sunflower genome provides insights into oil metabolism, flowering and Asterid evolution H Badouin, J Gouzy, CJ Grassa, F Murat, SE Staton, L Cottret, ... Nature 546 (7656), 148-152, 2017 | 667 | 2017 |
| NMR in drug discovery M Pellecchia, DS Sem, K Wüthrich Nature Reviews Drug Discovery 1 (3), 211-219, 2002 | 590 | 2002 |
| Apoptosis-based therapies for hematologic malignancies JC Reed, M Pellecchia Blood 106 (2), 408-418, 2005 | 535 | 2005 |
| Perspectives on NMR in drug discovery: a technique comes of age M Pellecchia, I Bertini, D Cowburn, C Dalvit, E Giralt, W Jahnke, TL James, ... Nature Reviews Drug Discovery 7 (9), 738-745, 2008 | 501 | 2008 |
| Discovery, characterization, and structure− activity relationships studies of proapoptotic polyphenols targeting B-cell lymphocyte/leukemia-2 proteins S Kitada, M Leone, S Sareth, D Zhai, JC Reed, M Pellecchia Journal of medicinal chemistry 46 (20), 4259-4264, 2003 | 487 | 2003 |
| Role of excitatory amino acid transporter‐2 (EAAT2) and glutamate in neurodegeneration: opportunities for developing novel therapeutics K Kim, SG Lee, TP Kegelman, ZZ Su, SK Das, R Dash, S Dasgupta, ... Journal of cellular physiology 226 (10), 2484-2493, 2011 | 465 | 2011 |
| Apoptosis-inducing factor triggered by poly (ADP-ribose) polymerase and Bid mediates neuronal cell death after oxygen-glucose deprivation and focal cerebral ischemia C Culmsee, C Zhu, S Landshamer, B Becattini, E Wagner, M Pellecchia, ... Journal of Neuroscience 25 (44), 10262-10272, 2005 | 439 | 2005 |
| Cancer prevention by tea polyphenols is linked to their direct inhibition of antiapoptotic Bcl-2-family proteins M Leone, D Zhai, S Sareth, S Kitada, JC Reed, M Pellecchia Cancer Research 63 (23), 8118-8121, 2003 | 370 | 2003 |
| A survey of the anti-apoptotic Bcl-2 subfamily expression in cancer types provides a platform to predict the efficacy of Bcl-2 antagonists in cancer therapy WJ Placzek, J Wei, S Kitada, D Zhai, JC Reed, M Pellecchia Cell death & disease 1 (5), e40-e40, 2010 | 355 | 2010 |
| Targeting the Bcl-2 family for cancer therapy S Thomas, BA Quinn, SK Das, R Dash, L Emdad, S Dasgupta, XY Wang, ... Expert opinion on therapeutic targets 17 (1), 61-75, 2013 | 311 | 2013 |
| Structural insights into substrate binding by the molecular chaperone DnaK M Pellecchia, DL Montgomery, SY Stevens, CW Vander Kooi, H Feng, ... Nature structural biology 7 (4), 298-303, 2000 | 275 | 2000 |
| Evolution and expansion of multidrug-resistant malaria in southeast Asia: a genomic epidemiology study WL Hamilton, R Amato, RW van der Pluijm, CG Jacob, HH Quang, ... The Lancet Infectious Diseases 19 (9), 943-951, 2019 | 263 | 2019 |
| NMR Structure of the J-domain and the Gly/Phe-rich Region of theEscherichia coliDnaJ Chaperone M Pellecchia, T Szyperski, D Wall, C Georgopoulos, K Wüthrich Journal of molecular biology 260 (2), 236-250, 1996 | 257 | 1996 |
| Targeting Mcl-1 for the therapy of cancer BA Quinn, R Dash, B Azab, S Sarkar, SK Das, S Kumar, RA Oyesanya, ... Expert opinion on investigational drugs 20 (10), 1397-1411, 2011 | 249 | 2011 |
| Identification of a new JNK inhibitor targeting the JNK-JIP interaction site JL Stebbins, SK De, T Machleidt, B Becattini, J Vazquez, C Kuntzen, ... Proceedings of the National Academy of Sciences 105 (43), 16809-16813, 2008 | 223 | 2008 |
| The epidemiology of subclinical malaria infections in South-East Asia: findings from cross-sectional surveys in Thailand–Myanmar border areas, Cambodia, and Vietnam M Imwong, TN Nguyen, R Tripura, TJ Peto, SJ Lee, KM Lwin, ... Malaria journal 14, 1-13, 2015 | 212 | 2015 |
| Rational design and real time, in-cell detection of the proapoptotic activity of a novel compound targeting Bcl-XL B Becattini, S Kitada, M Leone, E Monosov, S Chandler, D Zhai, TJ Kipps, ... Chemistry & biology 11 (3), 389-395, 2004 | 207 | 2004 |
| ADAR1 activation drives leukemia stem cell self-renewal by impairing Let-7 biogenesis MA Zipeto, A Sadarangani, NPD Santos, L Balaian, HJ Chun, G Pineda, ... Cell stem cell 19 (2), 177-191, 2016 | 201 | 2016 |
