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Patricia Pérez Galán
Patricia Pérez Galán
IDIBAPS
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Cited by
Year
The lymph node microenvironment promotes B-cell receptor signaling, NF-κB activation, and tumor proliferation in chronic lymphocytic leukemia
Y Herishanu, P Pérez-Galán, D Liu, A Biancotto, S Pittaluga, B Vire, ...
Blood, The Journal of the American Society of Hematology 117 (2), 563-574, 2011
10342011
The proteasome inhibitor bortezomib induces apoptosis in mantle-cell lymphoma through generation of ROS and Noxa activation independent of p53 status
P Pérez-Galán, G Roué, N Villamor, E Montserrat, E Campo, D Colomer
Blood 107 (1), 257-264, 2006
5392006
Mantle cell lymphoma: biology, pathogenesis, and the molecular basis of treatment in the genomic era
P Pérez-Galán, M Dreyling, A Wiestner
Blood, The Journal of the American Society of Hematology 117 (1), 26-38, 2011
4792011
ERAD inhibitors integrate ER stress with an epigenetic mechanism to activate BH3-only protein NOXA in cancer cells
Q Wang, H Mora-Jensen, MA Weniger, P Perez-Galan, C Wolford, T Hai, ...
Proceedings of the National Academy of Sciences 106 (7), 2200-2205, 2009
3792009
The BH3-mimetic GX15-070 synergizes with bortezomib in mantle cell lymphoma by enhancing Noxa-mediated activation of Bak
P Pérez-Galán, G Roué, N Villamor, E Campo, D Colomer
Blood 109 (10), 4441-4449, 2007
2412007
SOX11 regulates PAX5 expression and blocks terminal B-cell differentiation in aggressive mantle cell lymphoma
MC Vegliante, J Palomero, P Pérez-Galán, G Roué, G Castellano, ...
Blood, The Journal of the American Society of Hematology 121 (12), 2175-2185, 2013
2102013
Doxorubicin treatment activates a Z-VAD-sensitive caspase, which causes Δψm loss, caspase-9 activity, and apoptosis in Jurkat cells
S Gamen, A Anel, P Pérez-Galán, P Lasierra, D Johnson, A Piñeiro, ...
Experimental cell research 258 (1), 223-235, 2000
1742000
A role of the mitochondrial apoptosis-inducing factor in granulysin-induced apoptosis
J Pardo, P Pérez-Galán, S Gamen, I Marzo, I Monleón, AA Kaspar, ...
The Journal of Immunology 167 (3), 1222-1229, 2001
1472001
The Hsp90 inhibitor IPI-504 overcomes bortezomib resistance in mantle cell lymphoma in vitro and in vivo by down-regulation of the prosurvival ER chaperone BiP/Grp78
G Roué, P Pérez-Galán, A Mozos, M López-Guerra, S Xargay-Torrent, ...
Blood, The Journal of the American Society of Hematology 117 (4), 1270-1279, 2011
1272011
Cladribine induces apoptosis in human leukaemia cells by caspase-dependent and-independent pathways acting on mitochondria
I Marzo, P PÉREZ-GALÁN, P GIRALDO, D RUBIO-FÉLIX, A ANEL, ...
Biochemical Journal 359 (3), 537-546, 2001
1262001
Bortezomib resistance in mantle cell lymphoma is associated with plasmacytic differentiation
P Pérez-Galán, H Mora-Jensen, MA Weniger, AL Shaffer III, EG Rizzatti, ...
Blood, The Journal of the American Society of Hematology 117 (2), 542-552, 2011
1232011
Synergistic antitumor activity of lenalidomide with the BET bromodomain inhibitor CPI203 in bortezomib-resistant mantle cell lymphoma
A Moros, V Rodriguez, I Saborit-Villarroya, A Montraveta, P Balsas, ...
Leukemia 28 (10), 2049-2059, 2014
1152014
Treatment-induced oxidative stress and cellular antioxidant capacity determine response to bortezomib in mantle cell lymphoma
MA Weniger, EG Rizzatti, P Pérez-Galán, D Liu, Q Wang, PJ Munson, ...
Clinical Cancer Research 17 (15), 5101-5112, 2011
1052011
BCL-2 phosphorylation modulates sensitivity to the BH3 mimetic GX15-070 (Obatoclax) and reduces its synergistic interaction with bortezomib in chronic lymphocytic leukemia cells
P Perez-Galan, G Roue, M Lopez-Guerra, M Nguyen, N Villamor, ...
Leukemia 22 (9), 1712-1720, 2008
1042008
Bendamustine is effective in p53-deficient B-cell neoplasms and requires oxidative stress and caspase-independent signaling
G Roué, M López-Guerra, P Milpied, P Pérez-Galán, N Villamor, ...
Clinical cancer research 14 (21), 6907-6915, 2008
1022008
Modeling tumor–host interactions of chronic lymphocytic leukemia in xenografted mice to study tumor biology and evaluate targeted therapy
SEM Herman, X Sun, EM McAuley, MM Hsieh, S Pittaluga, M Raffeld, ...
Leukemia 27 (12), 2311-2321, 2013
1002013
Development of a novel anti-CD19 chimeric antigen receptor: a paradigm for an affordable CAR T cell production at academic institutions
M Castella, A Boronat, R Martín-Ibáñez, V Rodríguez, G Suñé, ...
Molecular Therapy-Methods & Clinical Development 12, 134-144, 2019
952019
Selective inhibition of IκB kinase sensitizes mantle cell lymphoma B cells to TRAIL by decreasing cellular FLIP level
G Roué, P Pérez-Galán, M López-Guerra, N Villamor, E Campo, ...
The Journal of Immunology 178 (3), 1923-1930, 2007
952007
Mantle cell lymphoma: from pathology and molecular pathogenesis to new therapeutic perspectives
I Salaverria, P Perez-Galan, D Colomer, E Campo
Haematologica 91 (1), 11-16, 2006
952006
The BET bromodomain inhibitor CPI203 overcomes resistance to ABT-199 (venetoclax) by downregulation of BFL-1/A1 in in vitro and in vivo models of MYC+/BCL2+ double hit lymphoma
A Esteve-Arenys, JG Valero, A Chamorro-Jorganes, D Gonzalez, ...
Oncogene 37 (14), 1830-1844, 2018
872018
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