MYC and MCL1 cooperatively promote chemotherapy-resistant breast cancer stem cells via regulation of mitochondrial oxidative phosphorylation K Lee, JM Giltnane, JM Balko, LJ Schwarz, AL Guerrero-Zotano, ... Cell metabolism 26 (4), 633-647. e7, 2017 | 502 | 2017 |
Aberrant FGFR signaling mediates resistance to CDK4/6 inhibitors in ER+ breast cancer L Formisano, Y Lu, A Servetto, AB Hanker, VM Jansen, JA Bauer, ... Nature communications 10 (1), 1373, 2019 | 299 | 2019 |
Health-related quality of life in disease-free survivors of breast cancer with the general population SH Ahn, BW Park, DY Noh, SJ Nam, ES Lee, MK Lee, SH Kim, KM Lee, ... Annals of Oncology 18 (1), 173-182, 2007 | 244 | 2007 |
Kinome-wide RNA interference screen reveals a role for PDK1 in acquired resistance to CDK4/6 inhibition in ER-positive breast cancer VM Jansen, NE Bhola, JA Bauer, L Formisano, KM Lee, KE Hutchinson, ... Cancer research 77 (9), 2488-2499, 2017 | 216 | 2017 |
A versatile oblique plane microscope for large-scale and high-resolution imaging of subcellular dynamics E Sapoznik, BJ Chang, J Huh, RJ Ju, EV Azarova, T Pohlkamp, ES Welf, ... Elife 9, e57681, 2020 | 134 | 2020 |
CD44 regulates cell proliferation, migration, and invasion via modulation of c-Src transcription in human breast cancer cells KS Nam, S Oh, K Lee, S Yoo, I Shin Cellular signalling 27 (9), 1882-1894, 2015 | 129 | 2015 |
ECM1 regulates tumor metastasis and CSC-like property through stabilization of β-catenin KM Lee, K Nam, S Oh, J Lim, RK Kim, D Shim, JH Choi, SJ Lee, JH Yu, ... Oncogene 34 (50), 6055-6065, 2015 | 99 | 2015 |
Regulation of cell proliferation and migration by keratin19-induced nuclear import of early growth response-1 in breast cancer cells J Ju, W Yang, K Lee, S Oh, KS Nam, S Shim, SY Shin, MC Gye, IS Chu, ... Clinical cancer research 19 (16), 4335-4346, 2013 | 83 | 2013 |
Extracellular matrix protein 1 regulates cell proliferation and trastuzumab resistance through activation of epidermal growth factor signaling K Lee, K Nam, S Oh, J Lim, YP Kim, JW Lee, JH Yu, SH Ahn, SB Kim, ... Breast Cancer Research 16, 1-17, 2014 | 68 | 2014 |
Elacestrant (RAD1901) exhibits anti-tumor activity in multiple ER+ breast cancer models resistant to CDK4/6 inhibitors HK Patel, N Tao, KM Lee, M Huerta, H Arlt, T Mullarkey, S Troy, ... Breast Cancer Research 21, 1-17, 2019 | 61 | 2019 |
CD24 enhances DNA damage-induced apoptosis by modulating NF-κB signaling in CD44-expressing breast cancer cells J Ju, K Jang, K Lee, M Kim, J Kim, JY Yi, DY Noh, I Shin Carcinogenesis 32 (10), 1474-1483, 2011 | 55 | 2011 |
Co-occurring gain-of-function mutations in HER2 and HER3 modulate HER2/HER3 activation, oncogenesis, and HER2 inhibitor sensitivity AB Hanker, BP Brown, J Meiler, A Marín, HS Jayanthan, D Ye, CC Lin, ... Cancer cell 39 (8), 1099-1114. e8, 2021 | 49 | 2021 |
Discovery of potent myeloid cell leukemia-1 (Mcl-1) inhibitors that demonstrate in vivo activity in mouse xenograft models of human cancer T Lee, PP Christov, S Shaw, JC Tarr, B Zhao, N Veerasamy, KO Jeon, ... Journal of medicinal chemistry 62 (8), 3971-3988, 2019 | 46 | 2019 |
Hyperactivation of TORC1 drives resistance to the pan-HER tyrosine kinase inhibitor neratinib in HER2-mutant cancers DR Sudhan, A Guerrero-Zotano, H Won, PG Ericsson, A Servetto, ... Cancer cell 37 (2), 183-199. e5, 2020 | 44 | 2020 |
Protein kinase B/Akt1 inhibits autophagy by down-regulating UVRAG expression W Yang, J Ju, K Lee, KS Nam, S Oh, I Shin Experimental cell research 319 (3), 122-133, 2013 | 44 | 2013 |
Cytokeratin19 induced by HER2/ERK binds and stabilizes HER2 on cell membranes JH Ju, S Oh, KM Lee, W Yang, KS Nam, HG Moon, DY Noh, CG Kim, ... Cell Death & Differentiation 22 (4), 665-676, 2015 | 43 | 2015 |
ECM1 promotes the Warburg effect through EGF-mediated activation of PKM2 K Lee, K Nam, S Oh, J Lim, T Lee, I Shin Cellular signalling 27 (2), 228-235, 2015 | 43 | 2015 |
Proline rich 11 (PRR11) overexpression amplifies PI3K signaling and promotes antiestrogen resistance in breast cancer K Lee, AL Guerrero-Zotano, A Servetto, DR Sudhan, CC Lin, L Formisano, ... Nature communications 11 (1), 5488, 2020 | 37 | 2020 |
Nuclear FGFR1 Regulates Gene Transcription and Promotes Antiestrogen Resistance in ER+ Breast Cancer A Servetto, R Kollipara, L Formisano, CC Lin, KM Lee, DR Sudhan, ... Clinical Cancer Research 27 (15), 4379-4396, 2021 | 36 | 2021 |
PIK3CA C2 Domain Deletions Hyperactivate Phosphoinositide 3-kinase (PI3K), Generate Oncogene Dependence, and Are Exquisitely Sensitive to PI3Kα Inhibitors S Croessmann, JH Sheehan, K Lee, G Sliwoski, J He, R Nagy, D Riddle, ... Clinical Cancer Research 24 (6), 1426-1435, 2018 | 34 | 2018 |