A first-in-human phase 0 clinical study of RNA interference–based spherical nucleic acids in patients with recurrent glioblastoma P Kumthekar, CH Ko, T Paunesku, K Dixit, AM Sonabend, O Bloch, M Tate, ... Science translational medicine 13 (584), eabb3945, 2021 | 158 | 2021 |
Mutant IDH1 and thrombosis in gliomas D Unruh, SR Schwarze, L Khoury, C Thomas, M Wu, L Chen, R Chen, ... Acta neuropathologica 132, 917-930, 2016 | 147 | 2016 |
Glioblastoma-derived IL6 induces immunosuppressive peripheral myeloid cell PD-L1 and promotes tumor growth JB Lamano, JB Lamano, YD Li, JD DiDomenico, W Choy, D Veliceasa, ... Clinical Cancer Research 25 (12), 3643-3657, 2019 | 144 | 2019 |
Human coronary artery perivascular adipocytes overexpress genes responsible for regulating vascular morphology, inflammation, and hemostasis TK Chatterjee, BJ Aronow, WS Tong, D Manka, Y Tang, VY Bogdanov, ... Physiological genomics 45 (16), 697-709, 2013 | 115 | 2013 |
Red blood cell dysfunction induced by high-fat diet: potential implications for obesity-related atherosclerosis D Unruh, R Srinivasan, T Benson, S Haigh, D Coyle, N Batra, R Keil, ... Circulation 132 (20), 1898-1908, 2015 | 98 | 2015 |
Beyond thrombosis: the impact of tissue factor signaling in cancer D Unruh, C Horbinski Journal of Hematology & Oncology 13 (1), 93, 2020 | 65 | 2020 |
Radiosensitization by histone H3 demethylase inhibition in diffuse intrinsic pontine glioma H Katagi, N Louis, D Unruh, T Sasaki, X He, A Zhang, Q Ma, A Piunti, ... Clinical cancer research 25 (18), 5572-5583, 2019 | 61 | 2019 |
Venous thromboembolism in brain tumors: risk factors, molecular mechanisms, and clinical challenges J Riedl, C Ay Seminars in thrombosis and hemostasis 45 (04), 334-341, 2019 | 58 | 2019 |
Alternatively spliced tissue factor contributes to tumor spread and activation of coagulation in pancreatic ductal adenocarcinoma D Unruh, K Turner, R Srinivasan, B Kocatürk, X Qi, Z Chu, BJ Aronow, ... International journal of cancer 134 (1), 9-20, 2014 | 58 | 2014 |
Methylation and transcription patterns are distinct in IDH mutant gliomas compared to other IDH mutant cancers D Unruh, M Zewde, A Buss, MR Drumm, AN Tran, DM Scholtens, ... Scientific reports 9 (1), 8946, 2019 | 55 | 2019 |
Microparticle association and heterogeneity of tumor‐derived tissue factor in plasma: is it important for coagulation activation? M Davila, L Robles‐Carrillo, D Unruh, Q Huo, C Gardiner, IL Sargent, ... Journal of Thrombosis and Haemostasis 12 (2), 186-196, 2014 | 53 | 2014 |
Tumor-induced peripheral immunosuppression promotes brain metastasis in patients with non-small cell lung cancer YD Li, JB Lamano, JB Lamano, J Quaggin-Smith, D Veliceasa, G Kaur, ... Cancer Immunology, Immunotherapy 68, 1501-1513, 2019 | 47 | 2019 |
Methylation-dependent tissue factor suppression contributes to the reduced malignancy of IDH1-mutant gliomas D Unruh, S Mirkov, B Wray, M Drumm, J Lamano, YD Li, QF Haider, ... Clinical Cancer Research 25 (2), 747-759, 2019 | 37 | 2019 |
Modeling the diffusion of D-2-hydroxyglutarate from IDH1 mutant gliomas in the central nervous system A Linninger, GA Hartung, BP Liu, S Mirkov, K Tangen, RV Lukas, D Unruh, ... Neuro-oncology 20 (9), 1197-1206, 2018 | 34 | 2018 |
Apolipoprotein AI and paraoxonase-1 are potential blood biomarkers for ischemic stroke diagnosis KB Walsh, K Hart, S Roll, M Sperling, D Unruh, WS Davidson, CJ Lindsell, ... Journal of Stroke and Cerebrovascular Diseases 25 (6), 1360-1365, 2016 | 33 | 2016 |
Levels of alternatively spliced tissue factor in the plasma of patients with pancreatic cancer may help predict aggressive tumor phenotype D Unruh, F Sagin, M Adam, P Van Dreden, BJ Woodhams, K Hart, ... Annals of surgical oncology 22, 1206-1211, 2015 | 33 | 2015 |
Antibody-based targeting of alternatively spliced tissue factor: a new approach to impede the primary growth and spread of pancreatic ductal adenocarcinoma D Unruh, B Ünlü, CS Lewis, X Qi, Z Chu, R Sturm, R Keil, SA Ahmad, ... Oncotarget 7 (18), 25264, 2016 | 24 | 2016 |
Procoagulant and proinflammatory effects of red blood cells on lipopolysaccharide‐stimulated monocytes B Østerud, D Unruh, JO Olsen, D Kirchhofer, AP Owens III, VY Bogdanov Journal of Thrombosis and Haemostasis 13 (9), 1676-1682, 2015 | 21 | 2015 |
Activation of carbonic anhydrase IX by alternatively spliced tissue factor under late-stage tumor conditions D Ramchandani, D Unruh, CS Lewis, VY Bogdanov, GF Weber Laboratory Investigation 96 (12), 1234-1245, 2016 | 17 | 2016 |
The ratio of factor VIIa: Tissue factor content within microvesicles determines the differential influence on endothelial cells Y Madkhali, S Featherby, ME Collier, A Maraveyas, J Greenman, ... TH Open 3 (02), e132-e145, 2019 | 15 | 2019 |