| Membrane transporters in drug development Nature reviews Drug discovery 9 (3), 215-236, 2010 | 3482 | 2010 |
| The UDP glycosyltransferase gene superfamily: recommended nomenclature update based on evolutionary divergence PI Mackenzie, IS Owens, B Burchell, KW Bock, A Bairoch, A Belanger, ... Pharmacogenetics and Genomics 7 (4), 255-269, 1997 | 1377 | 1997 |
| Nomenclature update for the mammalian UDP glycosyltransferase (UGT) gene superfamily PI Mackenzie, KW Bock, B Burchell, C Guillemette, S Ikushiro, T Iyanagi, ... Pharmacogenetics and genomics 15 (10), 677-685, 2005 | 971 | 2005 |
| The UDP-glucuronosyltransferases: their role in drug metabolism and detoxification A Rowland, JO Miners, PI Mackenzie The international journal of biochemistry & cell biology 45 (6), 1121-1132, 2013 | 691 | 2013 |
| Structural and functional studies of UDP-glucuronosyltransferases A Radominska-Pandya, PJ Czernik, JM Little, E Battaglia, PI Mackenzie Drug metabolism reviews 31 (4), 817-899, 1999 | 619 | 1999 |
| Drug glucuronidation in humans JO Miners, PI Mackenzie Pharmacology & therapeutics 51 (3), 347-369, 1991 | 462 | 1991 |
| Human UDP-glucuronosyltransferases: isoform selectivity and kinetics of 4-methylumbelliferone and 1-naphthol glucuronidation, effects of organic solvents, and inhibition by … V Uchaipichat, PI Mackenzie, XH Guo, D Gardner-Stephen, A Galetin, ... Drug Metabolism and Disposition 32 (4), 413-423, 2004 | 379 | 2004 |
| The UDP glucuronosyltransferase gene super family: suggested nomenclature based on evolutionary divergence B Burchell, DW Nebert, DR Nelson, KW Bock, T Iyanagi, PL Jansen, ... DNA and cell biology 10 (7), 487-494, 1991 | 344 | 1991 |
| Structure and function of uridine diphosphate glucuronosyltransferases R Meech, PI Mackenzie Clinical and experimental pharmacology and physiology 24 (12), 907-915, 1997 | 322 | 1997 |
| Glucuronidation and the UDP-glucuronosyltransferases in health and disease PG Wells, PI Mackenzie, JR Chowdhury, C Guillemette, PA Gregory, ... Drug metabolism and disposition 32 (3), 281-290, 2004 | 319 | 2004 |
| Glucuronidation of amines and other xenobiotics catalyzed by expressed human UDP-glucuronosyltransferase 1A3 MD Green, CD King, B Mojarrabi, PI Mackenzie, TR Tephly Drug Metabolism and Disposition 26 (6), 507-512, 1998 | 315 | 1998 |
| Genetic polymorphisms of UDP-glucuronosyltransferases and their functional significance JO Miners, RA McKinnon, PI Mackenzie Toxicology 181, 453-456, 2002 | 276 | 2002 |
| Complementary deoxyribonucleic acid cloning and expression of a human liver uridine diphosphate-glucuronosyltransferase glucuronidating carboxylic acid-containing drugs. C Jin, JO Miners, KJ Lillywhite, PI Mackenzie Journal of Pharmacology and Experimental Therapeutics 264 (1), 475-479, 1993 | 274 | 1993 |
| Tolbutamide and phenytoin hydroxylations by cDNA-expressed human liver cytochrome P4502C9 ME Veronese, PI Mackenzie, CJ Doecke, ME McManus, JO Miners, ... Biochemical and biophysical research communications 175 (3), 1112-1118, 1991 | 270 | 1991 |
| In vitro–in vivo correlation for drugs and other compounds eliminated by glucuronidation in humans: pitfalls and promises JO Miners, KM Knights, JB Houston, PI Mackenzie Biochemical pharmacology 71 (11), 1531-1539, 2006 | 262 | 2006 |
| The UDP-glycosyltransferase (UGT) superfamily: new members, new functions, and novel paradigms R Meech, DG Hu, RA McKinnon, SN Mubarokah, AZ Haines, PC Nair, ... Physiological Reviews 99 (2), 1153-1222, 2019 | 258 | 2019 |
| Selectivity of substrate (trifluoperazine) and inhibitor (amitriptyline, androsterone, canrenoic acid, hecogenin, phenylbutazone, quinidine, quinine, and sulfinpyrazone)“probes … V Uchaipichat, PI Mackenzie, DJ Elliot, JO Miners Drug metabolism and disposition 34 (3), 449-456, 2006 | 256 | 2006 |
| In vitro characterization of lamotrigine N2-glucuronidation and the lamotrigine-valproic acid interaction A Rowland, DJ Elliot, JA Williams, PI Mackenzie, RG Dickinson, ... Drug Metabolism and Disposition 34 (6), 1055-1062, 2006 | 255 | 2006 |
| The prediction of drug-glucuronidation parameters in humans: UDP-glucuronosyltransferase enzyme-selective substrate and inhibitor probes for reaction phenotyping and in vitro … JO Miners, PI Mackenzie, KM Knights Drug metabolism reviews 42 (1), 196-208, 2010 | 250 | 2010 |
| Predicting human drug glucuronidation parameters: application of in vitro and in silico modeling approaches JO Miners, PA Smith, MJ Sorich, RA McKinnon, PI Mackenzie Annu. Rev. Pharmacol. Toxicol. 44, 1-25, 2004 | 250 | 2004 |
