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Nilaksh Gupta
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Gut microbial metabolite TMAO enhances platelet hyperreactivity and thrombosis risk
W Zhu, JC Gregory, E Org, JA Buffa, N Gupta, Z Wang, L Li, X Fu, Y Wu, ...
Cell 165 (1), 111-124, 2016
16822016
A cardiovascular disease-linked gut microbial metabolite acts via adrenergic receptors
I Nemet, PP Saha, N Gupta, W Zhu, KA Romano, SM Skye, T Cajka, ...
Cell 180 (5), 862-877. e22, 2020
4512020
Development of a gut microbe–targeted nonlethal therapeutic to inhibit thrombosis potential
Nature Medicine, 2018
4392018
Targeted inhibition of gut microbial trimethylamine N-oxide production reduces renal tubulointerstitial fibrosis and functional impairment in a murine model of chronic kidney …
N Gupta, JA Buffa, AB Roberts, N Sangwan, SM Skye, L Li, KJ Ho, ...
Arteriosclerosis, thrombosis, and vascular biology 40 (5), 1239-1255, 2020
1312020
Flavin monooxygenase 3, the host hepatic enzyme in the metaorganismal trimethylamine N‐oxide‐generating pathway, modulates platelet responsiveness and thrombosis risk
W Zhu, JA Buffa, Z Wang, M Warrier, R Schugar, DM Shih, N Gupta, ...
Journal of Thrombosis and Haemostasis 16 (9), 1857-1872, 2018
1172018
The artificial sweetener erythritol and cardiovascular event risk
M Witkowski, I Nemet, H Alamri, J Wilcox, N Gupta, N Nimer, A Haghikia, ...
Nature medicine 29 (3), 710-718, 2023
852023
Nonlethal Inhibition of Gut Microbial Trimethylamine N‐oxide Production Improves Cardiac Function and Remodeling in a Murine Model of Heart Failure
CL Organ, Z Li, TE Sharp III, DJ Polhemus, N Gupta, TT Goodchild, ...
Journal of the American Heart Association 9 (10), e016223, 2020
732020
Proteasome proteolysis supports stimulated platelet function and thrombosis
N Gupta, W Li, B Willard, RL Silverstein, TM McIntyre
Arteriosclerosis, thrombosis, and vascular biology 34 (1), 160-168, 2014
662014
Deubiquitinases modulate platelet proteome ubiquitination, aggregation, and thrombosis
N Gupta, W Li, TM McIntyre
Arteriosclerosis, thrombosis, and vascular biology 35 (12), 2657-2666, 2015
292015
Gut microbe-derived metabolite trimethylamine N-oxide activates PERK to drive fibrogenic mesenchymal differentiation
SJ Kim, S Bale, P Verma, Q Wan, F Ma, JE Gudjonsson, SL Hazen, ...
Iscience 25 (7), 2022
62022
THE ORAL PROTEASOME INHIBITOR IXAZOMIB IN COMBINATION WITH MELPHALAN-PREDNISONE FOR PATIENTS WITH NEWLY DIAGNOSED MULTIPLE MYELOMA: PHASE 1/2 DOSE-ESCALATION STUDY (NCT01335685)
JS Miguel, MA Gutierrez, I Spicka, MV Mateos, K Song, M Craig, J Blade, ...
Haematologica 102, 111-112, 2017
22017
Ubiquitin-proteasome system modulates platelet function
N Gupta
Cleveland State University, 2014
22014
INHIBITION OF GUT MICROBIOTA-DEPENDENT TRIMETHYLAMINE N-OXIDE PRODUCTION RESCUES SYSTOLIC CARDIAC FUNCTION IN A MURINE MODEL OF RENAL DYSFUNCTION
R Bhandari, N Gupta, I Nemet, S Cameron, S Hazen
Journal of the American College of Cardiology 77 (18_Supplement_1), 3400-3400, 2021
2021
Studies on the fusion of myeloma cells with spleen cells
N Gupta
NDRI, KARNAL, 1990
1990
Y. Jia, N. Viswakarma, SE Crawford, J. Sarkar, M. Sambasiva Rao, WJ Karpus, YS Kanwar, Y.-J. Zhu, JK Reddy Early embryonic lethality of mice with disrupted transcription …
AJ Taylor, CW Beck, A Khan, A Nakamoto, S Okamoto, M Tai, ...
Gut Microbe-Derived Metabolite Trimethylamine N-Oxide Activates PERK to Drive Mesenchymal Differentiation and Fibrosis
S Kim, S Bale, Q Wan, J Gudjonsson, SL Hazen, PW Harms, PS Tsou, ...
Available at SSRN 3912949, 0
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