| C9ORF72 repeat expansion causes vulnerability of motor neurons to Ca2+-permeable AMPA receptor-mediated excitotoxicity BT Selvaraj, MR Livesey, C Zhao, JM Gregory, OT James, EM Cleary, ... Nature communications 9 (1), 347, 2018 | 187 | 2018 |
| Reactive astrocytes acquire neuroprotective as well as deleterious signatures in response to Tau and Aß pathology Z Jiwaji, SS Tiwari, RX Avilés-Reyes, M Hooley, D Hampton, M Torvell, ... Nature Communications 13 (1), 135, 2022 | 105 | 2022 |
| Mitochondrial bioenergetic deficits in C9orf72 amyotrophic lateral sclerosis motor neurons cause dysfunctional axonal homeostasis AR Mehta, JM Gregory, O Dando, RN Carter, K Burr, J Nanda, D Story, ... Acta neuropathologica 141, 257-279, 2021 | 92 | 2021 |
| TDP-43 as a potential biomarker for amyotrophic lateral sclerosis: a systematic review and meta-analysis V Majumder, JM Gregory, MA Barria, A Green, S Pal BMC neurology 18, 1-7, 2018 | 85 | 2018 |
| The chaperone HSPB8 reduces the accumulation of truncated TDP-43 species in cells and protects against TDP-43-mediated toxicity V Crippa, ME Cicardi, N Ramesh, SJ Seguin, M Ganassi, I Bigi, C Diacci, ... Human molecular genetics 25 (18), 3908-3924, 2016 | 83 | 2016 |
| The aggregation and neurotoxicity of TDP-43 and its ALS-associated 25 kDa fragment are differentially affected by molecular chaperones in Drosophila JM Gregory, TP Barros, S Meehan, CM Dobson, LM Luheshi PloS one 7 (2), e31899, 2012 | 78 | 2012 |
| Executive, language and fluency dysfunction are markers of localised TDP-43 cerebral pathology in non-demented ALS JM Gregory, K McDade, TH Bak, S Pal, S Chandran, C Smith, ... Journal of Neurology, Neurosurgery & Psychiatry 91 (2), 149-157, 2020 | 73 | 2020 |
| Genetics of amyotrophic lateral sclerosis JM Gregory, D Fagegaltier, H Phatnani, MB Harms Current Genetic Medicine Reports 8, 121-131, 2020 | 60 | 2020 |
| Clusterin protects neurons against intracellular proteotoxicity JM Gregory, DR Whiten, RA Brown, TP Barros, JR Kumita, JJ Yerbury, ... Acta Neuropathologica Communications 5, 1-16, 2017 | 58 | 2017 |
| Dysregulation of AMPA receptor subunit expression in sporadic ALS post‐mortem brain JM Gregory, MR Livesey, K McDade, BT Selvaraj, SK Barton, S Chandran, ... The Journal of pathology 250 (1), 67-78, 2020 | 46 | 2020 |
| Clinical trials in amyotrophic lateral sclerosis: a systematic review and perspective C Wong, M Stavrou, E Elliott, JM Gregory, N Leigh, AA Pinto, TL Williams, ... Brain Communications 3 (4), fcab242, 2021 | 38 | 2021 |
| Spatial transcriptomics identifies spatially dysregulated expression of GRM3 and USP47 in amyotrophic lateral sclerosis JM Gregory, K McDade, MR Livesey, I Croy, S Marion de Proce, T Aitman, ... Neuropathology and applied neurobiology 46 (5), 441-457, 2020 | 30 | 2020 |
| Targeting mitochondrial dysfunction in amyotrophic lateral sclerosis: a systematic review and meta-analysis AR Mehta, R Walters, FM Waldron, S Pal, BT Selvaraj, MR Macleod, ... Brain communications 1 (1), fcz009, 2019 | 27 | 2019 |
| NLRP3 inflammasome as a key molecular target underlying cognitive resilience in amyotrophic lateral sclerosis P Banerjee, E Elliott, OM Rifai, J O’Shaughnessy, K McDade, S Abrahams, ... The Journal of pathology 256 (3), 262-268, 2022 | 19 | 2022 |
| Neuronal clusterin expression is associated with cognitive protection in amyotrophic lateral sclerosis JM Gregory, E Elliott, K McDade, T Bak, S Pal, S Chandran, S Abrahams, ... Neuropathology and applied neurobiology 46 (3), 255-263, 2020 | 16 | 2020 |
| Motor neuron disease systematic multi-arm adaptive randomised trial (MND-SMART): a multi-arm, multi-stage, adaptive, platform, phase III randomised, double-blind, placebo … C Wong, RS Dakin, J Williamson, J Newton, M Steven, S Colville, ... BMJ open 12 (7), e064173, 2022 | 15 | 2022 |
| Probing TDP-43 condensation using an in silico designed aptamer E Zacco, O Kantelberg, E Milanetti, A Armaos, FP Panei, J Gregory, ... Nature Communications 13 (1), 3306, 2022 | 15 | 2022 |
| Cerebrospinal fluid cytotoxicity in amyotrophic lateral sclerosis: a systematic review of in vitro studies KC Ng Kee Kwong, JM Gregory, S Pal, S Chandran, AR Mehta Brain communications 2 (2), fcaa121, 2020 | 14 | 2020 |
| Improved detection of RNA foci in C9orf72 amyotrophic lateral sclerosis post-mortem tissue using BaseScope™ shows a lack of association with cognitive dysfunction AR Mehta, BT Selvaraj, SK Barton, K McDade, S Abrahams, S Chandran, ... Brain communications 2 (1), fcaa009, 2020 | 13 | 2020 |
| 40 years of CSF toxicity studies in ALS: what have we learnt about ALS pathophysiology? KC Ng Kee Kwong, PK Harbham, BT Selvaraj, JM Gregory, S Pal, ... Frontiers in Molecular Neuroscience 14, 647895, 2021 | 12 | 2021 |
Sharon AbrahamsUniversity of EdinburghVerified email at ed.ac.uk
