Renal biomarker qualification submission: a dialog between the FDA-EMEA and Predictive Safety Testing Consortium F Dieterle, F Sistare, F Goodsaid, M Papaluca, JS Ozer, CP Webb, W Baer, ... Nature biotechnology 28 (5), 455-462, 2010 | 470 | 2010 |
Kidney-on-a-chip technology for drug-induced nephrotoxicity screening MJ Wilmer, CP Ng, HL Lanz, P Vulto, L Suter-Dick, R Masereeuw Trends in biotechnology 34 (2), 156-170, 2016 | 380 | 2016 |
Gene expression in two hepatic cell lines, cultured primary hepatocytes, and liver slices compared to the in vivo liver gene expression in rats: possible implications for … F Boess, M Kamber, S Romer, R Gasser, D Muller, S Albertini, L Suter Toxicological Sciences 73 (2), 386-402, 2003 | 373 | 2003 |
A long-term three dimensional liver co-culture system for improved prediction of clinically relevant drug-induced hepatotoxicity R Kostadinova, F Boess, D Applegate, L Suter, T Weiser, T Singer, ... Toxicology and applied pharmacology 268 (1), 1-16, 2013 | 304 | 2013 |
Toxicogenomics in predictive toxicology in drug development L Suter, LE Babiss, EB Wheeldon Chemistry & biology 11 (2), 161-171, 2004 | 204 | 2004 |
Discriminating different classes of toxicants by transcript profiling G Steiner, L Suter, F Boess, R Gasser, MC de Vera, S Albertini, S Ruepp Environmental health perspectives 112 (12), 1236-1248, 2004 | 182 | 2004 |
Biomarker discovery by imaging mass spectrometry: transthyretin is a biomarker for gentamicin-induced nephrotoxicity in rat H Meistermann, JL Norris, HR Aerni, DS Cornett, A Friedlein, AR Erskine, ... Molecular & Cellular Proteomics 5 (10), 1876-1886, 2006 | 174 | 2006 |
Bioengineered 3D human kidney tissue, a platform for the determination of nephrotoxicity TM DesRochers, L Suter, A Roth, DL Kaplan PloS one 8 (3), e59219, 2013 | 160 | 2013 |
Two‐dimensional database of mouse liver proteins: Changes in hepatic protein levels following treatment with acetaminophen or its nontoxic regioisomer 3‐acetamidophenol M Fountoulakis, P Berndt, UA Boelsterli, F Crameri, M Winter, S Albertini, ... ELECTROPHORESIS: An International Journal 21 (11), 2148-2161, 2000 | 156 | 2000 |
The rat liver mitochondrial proteins M Fountoulakis, P Berndt, H Langen, L Suter Electrophoresis 23 (2), 311-328, 2002 | 123 | 2002 |
Nephrotoxicity and kidney transport assessment on 3D perfused proximal tubules MK Vormann, L Gijzen, S Hutter, L Boot, A Nicolas, A van den Heuvel, ... The AAPS journal 20, 1-11, 2018 | 120 | 2018 |
A label-free, impedance-based real time assay to identify drug-induced toxicities and differentiate cytostatic from cytotoxic effects S Kustermann, F Boess, A Buness, M Schmitz, M Watzele, T Weiser, ... Toxicology in Vitro 27 (5), 1589-1595, 2013 | 114 | 2013 |
Pro-fibrotic compounds induce stellate cell activation, ECM-remodelling and Nrf2 activation in a human 3D-multicellular model of liver fibrosis V Prestigiacomo, A Weston, S Messner, F Lampart, L Suter-Dick PloS one 12 (6), e0179995, 2017 | 95 | 2017 |
Proteomic analysis of the rat liver M Fountoulakis, L Suter Journal of chromatography B 782 (1-2), 197-218, 2002 | 91 | 2002 |
Screening of drug-transporter interactions in a 3D microfluidic renal proximal tubule on a chip J Vriend, TTG Nieskens, MK Vormann, BT van den Berge, ... The AAPS journal 20, 1-13, 2018 | 84 | 2018 |
EU framework 6 project: predictive toxicology (PredTox)—overview and outcome L Suter, S Schroeder, K Meyer, JC Gautier, A Amberg, M Wendt, ... Toxicology and applied pharmacology 252 (2), 73-84, 2011 | 83 | 2011 |
Toxicogenomics in the pharmaceutical industry: hollow promises or real benefit? A Lühe, L Suter, S Ruepp, T Singer, T Weiser, S Albertini Mutation Research/Fundamental and Molecular Mechanisms of Mutagenesis 575 (1 …, 2005 | 79 | 2005 |
Interlaboratory evaluation of rat hepatic gene expression changes induced by methapyrilene. JF Waring, RG Ulrich, N Flint, D Morfitt, A Kalkuhl, F Staedtler, M Lawton, ... Environmental health perspectives 112 (4), 439-448, 2004 | 79 | 2004 |
Modulation of gene and protein expression by carbon tetrachloride in the rat liver M Fountoulakis, MC de Vera, F Crameri, F Boess, R Gasser, S Albertini, ... Toxicology and applied pharmacology 183 (1), 71-80, 2002 | 77 | 2002 |
Two‐dimensional database of mouse liver proteins. An update M Fountoulakis, JF Juranville, P Berndt, H Langen, L Suter Electrophoresis 22 (9), 1747-1763, 2001 | 72 | 2001 |