A combined PD-1/C5a blockade synergistically protects against lung cancer growth and metastasis D Ajona, S Ortiz-Espinosa, H Moreno, T Lozano, MJ Pajares, J Agorreta, ... Cancer discovery 7 (7), 694-703, 2017 | 188 | 2017 |
Complementing the cancer-immunity cycle R Pio, D Ajona, S Ortiz-Espinosa, A Mantovani, JD Lambris Frontiers in immunology 10, 445513, 2019 | 171 | 2019 |
Complement anaphylatoxins C3a and C5a: Emerging roles in cancer progression and treatment D Ajona, S Ortiz-Espinosa, R Pio Seminars in cell & developmental biology 85, 153-163, 2019 | 107 | 2019 |
Short-term starvation reduces IGF-1 levels to sensitize lung tumors to PD-1 immune checkpoint blockade D Ajona, S Ortiz-Espinosa, T Lozano, F Exposito, A Calvo, K Valencia, ... Nature Cancer 1 (1), 75-85, 2020 | 88 | 2020 |
Blockade of the complement C5a/C5aR1 axis impairs lung cancer bone metastasis by CXCL16-mediated effects D Ajona, C Zandueta, L Corrales, H Moreno, MJ Pajares, ... American journal of respiratory and critical care medicine 197 (9), 1164-1176, 2018 | 66 | 2018 |
Complement C5a induces the formation of neutrophil extracellular traps by myeloid-derived suppressor cells to promote metastasis S Ortiz-Espinosa, X Morales, Y Senent, D Alignani, B Tavira, I Macaya, ... Cancer letters 529, 70-84, 2022 | 57 | 2022 |
SRC family kinase (SFK) inhibitor dasatinib improves the antitumor activity of anti-PD-1 in NSCLC models by inhibiting Treg cell conversion and proliferation E Redin, I Garmendia, T Lozano, D Serrano, Y Senent, M Redrado, ... Journal for immunotherapy of cancer 9 (3), 2021 | 48 | 2021 |
Complement in metastasis: a comp in the camp D Ajona, S Ortiz-Espinosa, R Pio, F Lecanda Frontiers in Immunology 10, 669, 2019 | 37 | 2019 |
FOSL1 promotes cholangiocarcinoma via transcriptional effectors that could be therapeutically targeted A Vallejo, O Erice, R Entrialgo-Cadierno, I Feliu, E Guruceaga, ... Journal of Hepatology 75 (2), 363-376, 2021 | 32 | 2021 |
Tumor ENPP1 (CD203a)/Haptoglobin axis exploits myeloid-derived suppressor cells to promote post-radiotherapy local recurrence in breast cancer B Ruiz-Fernandez de Cordoba, H Moreno, K Valencia, N Perurena, ... Cancer discovery 12 (5), 1356-1377, 2022 | 28 | 2022 |
Id1 and PD-1 combined blockade impairs tumor growth and survival of KRAS-mutant lung cancer by stimulating PD-L1 expression and tumor infiltrating CD8+ T cells I Baraibar, M Roman, M Rodríguez-Remírez, I López, A Vilalta, ... Cancers 12 (11), 3169, 2020 | 12 | 2020 |
A combined PD-1/C5a blockade synergistically protects against lung cancer growth and metastasis. Cancer Discov. 2017; 7 (7): 694–703. doi: 10.1158/2159-8290 D Ajona, S Ortiz-Espinosa, H Moreno, T Lozano, MJ Pajares, J Agorreta, ... CD-16-1184.[Abstract][CrossRef][Google Scholar], 0 | 9 | |
Design and validation of a tunable inertial microfluidic system for the efficient enrichment of circulating tumor cells in blood A Rodríguez‐Pena, E Armendariz, A Oyarbide, X Morales, ... Bioengineering & Translational Medicine 7 (3), e10331, 2022 | 6 | 2022 |
Gene knock-outs in human CD34+ hematopoietic stem and progenitor cells and in the human immune system of mice DA Kuppers, J Linton, S Ortiz Espinosa, KM McKenna, A Rongvaux, ... Plos one 18 (6), e0287052, 2023 | 2 | 2023 |
Bursting Tumor Bubbles to Improve CAR T-cell Therapy S Ortiz-Espinosa, S Srivastava Cancer Research 83 (16), 2637-2639, 2023 | 1 | 2023 |
MA11. 06 Prognostic Value of Complement System in NSCLC and its Association with PD-1 and PD-L1 Expression D Ajona, MJ Pajares, J Freire, J Gomez-Roman, E Martinez-Terroba, ... Journal of Thoracic Oncology 13 (10), S394, 2018 | 1 | 2018 |
P3. 07-007 Blockade of the Complement C5a/C5aR1 Axis Impairs Lung Cancer Bone Metastasis D Ajona, C Zandueta, L Corrales, H Moreno, M Pajares, S Ortiz-Espinosa, ... Journal of Thoracic Oncology 12 (11), S2300, 2017 | 1 | 2017 |
Abstract B024: TrkB. T1 receptor promotes an immunosuppressive microenvironment driven by neutrophil recruitment in gliomas L Merino-Galan, S Ortiz-Espinosa, M Hathaway, A Rajendran, HL Jagana, ... Cancer Immunology Research 11 (12_Supplement), B024-B024, 2023 | | 2023 |
Abstract B025: Neutrophil depletion enhances the anti-tumor activity of CAR-T cells in an autochthonous model of non-small cell lung cancer S Ortiz-Espinosa, S Srivastava Cancer Immunology Research 11 (12_Supplement), B025-B025, 2023 | | 2023 |
FP03. 04 Dasatinib Improves the Antitumor Activity of Anti-PD-1 in NSCLC Models by Inhibiting Treg Conversion and Proliferation E Redin, I Garmendia, T Lozano, D Serrano, Y Senent, M Redrado, ... Journal of Thoracic Oncology 16 (10), S949, 2021 | | 2021 |