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Sergio Ortiz Espinosa
Sergio Ortiz Espinosa
Postdoctoral Fellow at Fred Hutchinson Cancer Center
Verified email at fredhutch.org
Title
Cited by
Cited by
Year
A combined PD-1/C5a blockade synergistically protects against lung cancer growth and metastasis
D Ajona, S Ortiz-Espinosa, H Moreno, T Lozano, MJ Pajares, J Agorreta, ...
Cancer discovery 7 (7), 694-703, 2017
1882017
Complementing the cancer-immunity cycle
R Pio, D Ajona, S Ortiz-Espinosa, A Mantovani, JD Lambris
Frontiers in immunology 10, 445513, 2019
1712019
Complement anaphylatoxins C3a and C5a: Emerging roles in cancer progression and treatment
D Ajona, S Ortiz-Espinosa, R Pio
Seminars in cell & developmental biology 85, 153-163, 2019
1072019
Short-term starvation reduces IGF-1 levels to sensitize lung tumors to PD-1 immune checkpoint blockade
D Ajona, S Ortiz-Espinosa, T Lozano, F Exposito, A Calvo, K Valencia, ...
Nature Cancer 1 (1), 75-85, 2020
882020
Blockade of the complement C5a/C5aR1 axis impairs lung cancer bone metastasis by CXCL16-mediated effects
D Ajona, C Zandueta, L Corrales, H Moreno, MJ Pajares, ...
American journal of respiratory and critical care medicine 197 (9), 1164-1176, 2018
662018
Complement C5a induces the formation of neutrophil extracellular traps by myeloid-derived suppressor cells to promote metastasis
S Ortiz-Espinosa, X Morales, Y Senent, D Alignani, B Tavira, I Macaya, ...
Cancer letters 529, 70-84, 2022
572022
SRC family kinase (SFK) inhibitor dasatinib improves the antitumor activity of anti-PD-1 in NSCLC models by inhibiting Treg cell conversion and proliferation
E Redin, I Garmendia, T Lozano, D Serrano, Y Senent, M Redrado, ...
Journal for immunotherapy of cancer 9 (3), 2021
482021
Complement in metastasis: a comp in the camp
D Ajona, S Ortiz-Espinosa, R Pio, F Lecanda
Frontiers in Immunology 10, 669, 2019
372019
FOSL1 promotes cholangiocarcinoma via transcriptional effectors that could be therapeutically targeted
A Vallejo, O Erice, R Entrialgo-Cadierno, I Feliu, E Guruceaga, ...
Journal of Hepatology 75 (2), 363-376, 2021
322021
Tumor ENPP1 (CD203a)/Haptoglobin axis exploits myeloid-derived suppressor cells to promote post-radiotherapy local recurrence in breast cancer
B Ruiz-Fernandez de Cordoba, H Moreno, K Valencia, N Perurena, ...
Cancer discovery 12 (5), 1356-1377, 2022
282022
Id1 and PD-1 combined blockade impairs tumor growth and survival of KRAS-mutant lung cancer by stimulating PD-L1 expression and tumor infiltrating CD8+ T cells
I Baraibar, M Roman, M Rodríguez-Remírez, I López, A Vilalta, ...
Cancers 12 (11), 3169, 2020
122020
A combined PD-1/C5a blockade synergistically protects against lung cancer growth and metastasis. Cancer Discov. 2017; 7 (7): 694–703. doi: 10.1158/2159-8290
D Ajona, S Ortiz-Espinosa, H Moreno, T Lozano, MJ Pajares, J Agorreta, ...
CD-16-1184.[Abstract][CrossRef][Google Scholar], 0
9
Design and validation of a tunable inertial microfluidic system for the efficient enrichment of circulating tumor cells in blood
A Rodríguez‐Pena, E Armendariz, A Oyarbide, X Morales, ...
Bioengineering & Translational Medicine 7 (3), e10331, 2022
62022
Gene knock-outs in human CD34+ hematopoietic stem and progenitor cells and in the human immune system of mice
DA Kuppers, J Linton, S Ortiz Espinosa, KM McKenna, A Rongvaux, ...
Plos one 18 (6), e0287052, 2023
22023
Bursting Tumor Bubbles to Improve CAR T-cell Therapy
S Ortiz-Espinosa, S Srivastava
Cancer Research 83 (16), 2637-2639, 2023
12023
MA11. 06 Prognostic Value of Complement System in NSCLC and its Association with PD-1 and PD-L1 Expression
D Ajona, MJ Pajares, J Freire, J Gomez-Roman, E Martinez-Terroba, ...
Journal of Thoracic Oncology 13 (10), S394, 2018
12018
P3. 07-007 Blockade of the Complement C5a/C5aR1 Axis Impairs Lung Cancer Bone Metastasis
D Ajona, C Zandueta, L Corrales, H Moreno, M Pajares, S Ortiz-Espinosa, ...
Journal of Thoracic Oncology 12 (11), S2300, 2017
12017
Abstract B024: TrkB. T1 receptor promotes an immunosuppressive microenvironment driven by neutrophil recruitment in gliomas
L Merino-Galan, S Ortiz-Espinosa, M Hathaway, A Rajendran, HL Jagana, ...
Cancer Immunology Research 11 (12_Supplement), B024-B024, 2023
2023
Abstract B025: Neutrophil depletion enhances the anti-tumor activity of CAR-T cells in an autochthonous model of non-small cell lung cancer
S Ortiz-Espinosa, S Srivastava
Cancer Immunology Research 11 (12_Supplement), B025-B025, 2023
2023
FP03. 04 Dasatinib Improves the Antitumor Activity of Anti-PD-1 in NSCLC Models by Inhibiting Treg Conversion and Proliferation
E Redin, I Garmendia, T Lozano, D Serrano, Y Senent, M Redrado, ...
Journal of Thoracic Oncology 16 (10), S949, 2021
2021
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