| SOD1 mutations disrupt redox-sensitive Rac regulation of NADPH oxidase in a familial ALS model MM Harraz, JJ Marden, W Zhou, Y Zhang, A Williams, VS Sharov, ... The Journal of clinical investigation 118 (2), 659-670, 2008 | 428 | 2008 |
| Polyglutamine neurodegeneration: protein misfolding revisited AJ Williams, HL Paulson Trends in neurosciences 31 (10), 521-528, 2008 | 412 | 2008 |
| The deubiquitinating enzyme ataxin-3, a polyglutamine disease protein, edits Lys63 linkages in mixed linkage ubiquitin chains BJ Winborn, SM Travis, SV Todi, KM Scaglione, P Xu, AJ Williams, ... Journal of Biological Chemistry 283 (39), 26436-26443, 2008 | 316 | 2008 |
| CHIP suppresses polyglutamine aggregation and toxicity in vitro and in vivo VM Miller, RF Nelson, CM Gouvion, A Williams, E Rodriguez-Lebron, ... Journal of Neuroscience 25 (40), 9152-9161, 2005 | 299 | 2005 |
| Live-cell imaging reveals divergent intracellular dynamics of polyglutamine disease proteins and supports a sequestration model of pathogenesis Y Chai, J Shao, VM Miller, A Williams, HL Paulson Proceedings of the National Academy of Sciences 99 (14), 9310-9315, 2002 | 251 | 2002 |
| Redox modifier genes in amyotrophic lateral sclerosis in mice JJ Marden, MM Harraz, AJ Williams, K Nelson, M Luo, H Paulson, ... The Journal of clinical investigation 117 (10), 2913-2919, 2007 | 179 | 2007 |
| The Machado–Joseph disease-associated mutant form of ataxin-3 regulates parkin ubiquitination and stability TM Durcan, M Kontogiannea, T Thorarinsdottir, L Fallon, AJ Williams, ... Human molecular genetics 20 (1), 141-154, 2011 | 173 | 2011 |
| In vivo suppression of polyglutamine neurotoxicity by C-terminus of Hsp70-interacting protein (CHIP) supports an aggregation model of pathogenesis AJ Williams, TM Knutson, VFC Gould, HL Paulson Neurobiology of disease 33 (3), 342-353, 2009 | 114 | 2009 |
| JosD1, a membrane-targeted deubiquitinating enzyme, is activated by ubiquitination and regulates membrane dynamics, cell motility, and endocytosis T Seki, L Gong, AJ Williams, N Sakai, SV Todi, HL Paulson Journal of Biological Chemistry 288 (24), 17145-17155, 2013 | 76 | 2013 |
| IP3 receptors and associated Ca2+ signals localize to satellite cells and to components of the neuromuscular junction in skeletal muscle JA Powell, J Molgó, DS Adams, C Colasante, A Williams, MK Bohlen, ... Journal of Neuroscience 23 (23), 8185-8192, 2003 | 56 | 2003 |
| Intentional mentoring: maximizing the impact of underrepresented future scientists in the 21st century H Shuler, V Cazares, A Marshall, E Garza-Lopez, R Hultman, TK Francis, ... Pathogens and disease 79 (6), ftab038, 2021 | 48 | 2021 |
| The best-laid plans go oft awry: synaptogenic growth factor signaling in neuropsychiatric disease AJ Williams, H Umemori Frontiers in synaptic neuroscience 6, 4, 2014 | 35 | 2014 |
| SCN2A channelopathies in the autism spectrum of neuropsychiatric disorders: a role for pluripotent stem cells? KA Kruth, TM Grisolano, CA Ahern, AJ Williams Molecular autism 11, 1-11, 2020 | 28 | 2020 |
| Deletion of fibroblast growth factor 22 (FGF22) causes a depression-like phenotype in adult mice AJ Williams, P Yee, MC Smith, GG Murphy, H Umemori Behavioural brain research 307, 11-17, 2016 | 27 | 2016 |
| Polyglutamine disorders including huntington’s disease SV Todi, AJ Williams, HL Paulson Molecular neurology, 257-276, 2007 | 26 | 2007 |
| Risk factors associated with antidepressant exposure and history of antidepressant-induced mania in bipolar disorder AJ Williams, Z Lai, S Knight, M Kamali, S Assari, MG McInnis The Journal of clinical psychiatry 79 (3), 913, 2018 | 21 | 2018 |
| Metabolic abnormalities in the basal ganglia and cerebellum in bipolar disorder: A multi-modal MR study VA Magnotta, J Xu, JG Fiedorowicz, A Williams, J Shaffer, G Christensen, ... Journal of affective disorders 301, 390-399, 2022 | 15 | 2022 |
| Atypical psychotic symptoms and Dandy–Walker variant AJ Williams, Z Wang, SF Taylor Neurocase 22 (5), 472-475, 2016 | 11 | 2016 |
| Distinct patterns of altered quantitative T1ρ and functional BOLD response associated with history of suicide attempts in bipolar disorder JJ Shaffer, V Willour, JG Fiedorowicz, GE Christensen, JD Long, ... Brain imaging and behavior, 1-14, 2022 | 9 | 2022 |
| Functional connectivity of the cerebellar vermis in bipolar disorder and associations with mood A Saleem, G Harmata, S Jain, MW Voss, JG Fiedorowicz, AJ Williams, ... Frontiers in psychiatry 14, 1147540, 2023 | 8 | 2023 |
