| Brain-related proteins as serum biomarkers of acute, subconcussive blast overpressure exposure: a cohort study of military personnel AM Boutte, B Thangavelu, CR LaValle, J Nemes, J Gilsdorf, DA Shear, ... PLoS one 14 (8), e0221036, 2019 | 44 | 2019 |
| Neurotrauma biomarker levels and adverse symptoms among military and law enforcement personnel exposed to occupational overpressure without diagnosed traumatic brain injury AM Boutté, B Thangavelu, J Nemes, CR LaValle, M Egnoto, W Carr, ... JAMA Network Open 4 (4), e216445-e216445, 2021 | 31 | 2021 |
| Overpressure exposure from. 50-caliber rifle training is associated with increased amyloid beta peptides in serum B Thangavelu, CR LaValle, MJ Egnoto, J Nemes, AM Boutté, ... Frontiers in neurology 11, 489162, 2020 | 19 | 2020 |
| Design and optimization of aspartate N-acetyltransferase inhibitors for the potential treatment of Canavan disease B Thangavelu, V Mutthamsetty, Q Wang, RE Viola Bioorganic & medicinal chemistry 25 (3), 870-885, 2017 | 18 | 2017 |
| Elaboration of a fragment library hit produces potent and selective aspartate semialdehyde dehydrogenase inhibitors B Thangavelu, P Bhansali, RE Viola Bioorganic & medicinal chemistry 23 (20), 6622-6631, 2015 | 18 | 2015 |
| Penetrating ballistic-like brain injury leads to microRNA dysregulation, BACE1 upregulation, and amyloid precursor protein loss in lesioned rat brain tissues B Thangavelu, BS Wilfred, D Johnson, JS Gilsdorf, DA Shear, AM Boutté Frontiers in neuroscience 14, 558952, 2020 | 17 | 2020 |
| Penetrating traumatic brain injury triggers dysregulation of cathepsin B protein levels independent of cysteine protease activity in brain and cerebral spinal fluid AM Boutté, V Hook, B Thangavelu, GA Sarkis, BN Abbatiello, G Hook, ... Journal of neurotrauma 37 (13), 1574-1586, 2020 | 14 | 2020 |
| Single molecule assay for ultrasensitive detection of cathepsin B in human blood B Thangavelu, AM Boutté ACS omega 6 (14), 9609-9616, 2021 | 13 | 2021 |
| Structure of homoserine O-acetyltransferase from Staphylococcus aureus: the first Gram-positive ortholog structure B Thangavelu, AG Pavlovsky, R Viola Acta Crystallographica Section F: Structural Biology Communications 70 (10 …, 2014 | 13 | 2014 |
| A cautionary tale of structure-guided inhibitor development against an essential enzyme in the aspartate-biosynthetic pathway AG Pavlovsky, B Thangavelu, P Bhansali, RE Viola Acta Crystallographica Section D: Biological Crystallography 70 (12), 3244-3252, 2014 | 12 | 2014 |
| Opinion: The Potential role of amyloid beta peptides as biomarkers of subconcussion and concussion AM Boutté, B Thangavelu, J Anagli Frontiers in neurology 13, 941151, 2022 | 3 | 2022 |
| Potent phthalate inhibitors of aspartate N-acetyltransferase and selective aspartate pathway inhibitors RE Viola, B Thangavelu, V Mutthamsetty, Q Wang, P Bhansali US Patent 10,449,168, 2019 | 1 | 2019 |
| Targeted quantitation of serum protein biomarkers in response to blast overpressure exposure among military breachers AM Boutte, B Thangavelu, CR Lavalle, JS Gilsdorf, DA Shearl, ... JOURNAL OF NEUROTRAUMA 35 (16), A213-A214, 2018 | 1 | 2018 |
| Alternative microbial routes to homoserine activation and sulfuration: critical steps in methionine biosynthesis REV Bharani Thangavelu International Journal of Biochemistry Research & Review 11 (3), 2016 | 1 | 2016 |
| Potent inhibitors of aspartate N-acetyl-transferase for the treatment of Canavan disease RE Viola, B Thangavelu, V Mutthamsetty, Q Wang US Patent 11,186,541, 2021 | | 2021 |
| Dataset of Rat and Human Serum Proteomes Derived from Differential Depletion Strategies prior to Mass Spectrometry B Thangavelu, GH Kamimori, JS Gilsdorf, DA Shear, AM Boutté Data in Brief 30, 105657, 2020 | | 2020 |
| IMPACT OF CYSTEINE PROTEASE INHIBITOR, E-64D, PROTEASE ACTIVITY AND PROTEIN BIOMARKER LEVELS AFTER BRAIN INJURY B Thangavelu, J Gilsdorf, DA Shear, AM Boutte JOURNAL OF NEUROTRAUMA 35 (16), A83-A83, 2018 | | 2018 |
| Development of amino acid-based inhibitors against Aspartate-N-Acetyltransferase (ANAT) for the treatment of Canavan disease V Mutthamsetty, B Thangavelu, Q Wang, R Viola ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY 253, 2017 | | 2017 |
| Aspartate N‐acetyltransferase: a key enzyme in neurobiology and cancer Q Wang, M Zhao, GG Parungao, B Thangavelu, V Mutthamsetty, RE Viola The FASEB Journal 31, 921.21-921.21, 2017 | | 2017 |
| Substrate reduction therapy for Canavan disease Q Wang, M Zhao, G Parungao, B Thangavelu, V Mutthamsetty, R Viola ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY 252, 2016 | | 2016 |
Ronald ViolaUniversity of ToledoVerified email at utoledo.edu
