| Activating gene expression in mammalian cells with promoter-targeted duplex RNAs BA Janowski, ST Younger, DB Hardy, R Ram, KE Huffman, DR Corey Nature chemical biology 3 (3), 166-173, 2007 | 637 | 2007 |
| Antisense transcripts are targets for activating small RNAs JC Schwartz, ST Younger, NB Nguyen, DB Hardy, BP Monia, DR Corey, ... Nature structural & molecular biology 15 (8), 842-848, 2008 | 353 | 2008 |
| Multiplexable, locus-specific targeting of long RNAs with CRISPR-Display DM Shechner, E Hacisuleyman, ST Younger, JL Rinn Nature methods 12 (7), 664-670, 2015 | 319 | 2015 |
| Orthologous CRISPR–Cas9 enzymes for combinatorial genetic screens FJ Najm, C Strand, KF Donovan, M Hegde, KR Sanson, EW Vaimberg, ... Nature biotechnology 36 (2), 179-189, 2018 | 273 | 2018 |
| Transcriptional gene silencing in mammalian cells by miRNA mimics that target gene promoters ST Younger, DR Corey Nucleic acids research 39 (13), 5682-5691, 2011 | 234 | 2011 |
| Involvement of argonaute proteins in gene silencing and activation by RNAs complementary to a non-coding transcript at the progesterone receptor promoter Y Chu, X Yue, ST Younger, BA Janowski, DR Corey Nucleic acids research 38 (21), 7736-7748, 2010 | 184 | 2010 |
| Agreement between two large pan-cancer CRISPR-Cas9 gene dependency data sets JM Dempster, C Pacini, S Pantel, FM Behan, T Green, J Krill-Burger, ... Nature communications 10 (1), 5817, 2019 | 180 | 2019 |
| Cells Lacking the RB1 Tumor Suppressor Gene Are Hyperdependent on Aurora B Kinase for Survival MG Oser, R Fonseca, AA Chakraborty, R Brough, A Spektor, RB Jennings, ... Cancer discovery 9 (2), 230-247, 2019 | 138 | 2019 |
| Modulation of gene expression through endogenous small RNA targeting of gene promoters DR Corey, ST Younger US Patent 8,222,221, 2012 | 132 | 2012 |
| Deubiquitinases maintain protein homeostasis and survival of cancer cells upon glutathione depletion IS Harris, JE Endress, JL Coloff, LM Selfors, SK McBrayer, JM Rosenbluth, ... Cell metabolism 29 (5), 1166-1181. e6, 2019 | 126 | 2019 |
| Transcriptional regulation by small RNAs at sequences downstream from 3′ gene termini X Yue, JC Schwartz, Y Chu, ST Younger, KT Gagnon, S Elbashir, ... Nature chemical biology 6 (8), 621, 2010 | 121 | 2010 |
| Integrative genomic analysis reveals widespread enhancer regulation by p53 in response to DNA damage ST Younger, D Kenzelmann-Broz, H Jung, LD Attardi, JL Rinn Nucleic acids research 43 (9), 4447-4462, 2015 | 92 | 2015 |
| Predicting potential miRNA target sites within gene promoters ST Younger, A Pertsemlidis, DR Corey Bioorganic & medicinal chemistry letters 19 (14), 3791-3794, 2009 | 83 | 2009 |
| p53 regulates enhancer accessibility and activity in response to DNA damage ST Younger, JL Rinn Nucleic acids research 45 (17), 9889-9900, 2017 | 59 | 2017 |
| Genomic answers for children: Dynamic analyses of> 1000 pediatric rare disease genomes ASA Cohen, EG Farrow, AT Abdelmoity, JT Alaimo, SM Amudhavalli, ... Genetics in Medicine 24 (6), 1336-1348, 2022 | 53 | 2022 |
| An In Vivo CRISPR Screening Platform for Prioritizing Therapeutic Targets in AML S Lin, C Larrue, NK Scheidegger, BKA Seong, NV Dharia, M Kuljanin, ... Cancer discovery 12 (2), 432-449, 2022 | 42 | 2022 |
| Transcriptional regulation by miRNA mimics that target sequences downstream of gene termini ST Younger, DR Corey Molecular BioSystems 7 (8), 2383-2388, 2011 | 40 | 2011 |
| LKB1/STK11 Is a Tumor Suppressor in the Progression of Myeloproliferative Neoplasms C Marinaccio, P Suraneni, H Celik, A Volk, QJ Wen, T Ling, M Bulic, ... Cancer discovery 11 (6), 1398-1410, 2021 | 35 | 2021 |
| Modulating Gene Expression with agRNA and Gapmers Targeting Antisense Transcripts JC Schwartz, ST Younger, BA Janowski, DR Corey US Patent App. 12/246,421, 2009 | 30 | 2009 |
| 'Lnc'-ing enhancers to MYC regulation ST Younger, JL Rinn Cell research 24 (6), 643-644, 2014 | 28 | 2014 |
