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Rekha C. Patel
Rekha C. Patel
Professor of Biological Sciences, University of South Carolina
Verified email at biol.sc.edu - Homepage
Title
Cited by
Cited by
Year
PACT, a protein activator of the interferon‐induced protein kinase, PKR
RC Patel, GC Sen
The EMBO journal, 1998
5801998
PACT, a stress-modulated cellular activator of interferon-induced double-stranded RNA-activated protein kinase, PKR
CV Patel, I Handy, T Goldsmith, RC Patel
Journal of Biological Chemistry 275 (48), 37993-37998, 2000
2822000
The interferon-inducible double-stranded RNA-activated protein kinase self-associates in vitro and in vivo.
RC Patel, P Stanton, NM McMillan, BR Williams, GC Sen
Proceedings of the National Academy of Sciences 92 (18), 8283-8287, 1995
2011995
Identification of the double-stranded RNA-binding domain of the human interferon-inducible protein kinase.
RC Patel, GC Sen
Journal of Biological Chemistry 267 (11), 7671-7676, 1992
1671992
DRBP76, a double-stranded RNA-binding nuclear protein, is phosphorylated by the interferon-induced protein kinase, PKR
RC Patel, DJ Vestal, Z Xu, S Bandyopadhyay, W Guo, SM Erme, ...
Journal of Biological Chemistry 274 (29), 20432-20437, 1999
1541999
TRBP control of PACT-induced phosphorylation of protein kinase R is reversed by stress
A Daher, G Laraki, M Singh, CE Melendez-Pena, S Bannwarth, ...
Molecular and cellular biology, 2009
1462009
Specific mutations near the amino terminus of double-stranded RNA-dependent protein kinase (PKR) differentially affect its double-stranded RNA binding and dimerization properties
RC Patel, P Stanton, GC Sen
Journal of Biological Chemistry 271 (41), 25657-25663, 1996
1111996
The C-terminal, third conserved motif of the protein activator PACT plays an essential role in the activation of double-stranded-RNA-dependent protein kinase (PKR)
X Huang, B Hutchins, RC Patel
Biochemical Journal 366 (1), 175-186, 2002
952002
Activation of Interferon-inducible 2′− 5′ Oligoadenylate Synthetase by Adenoviral VAI RNA (∗)
SY Desai, RC Patel, GC Sen, P Malhotra, GD Ghadge, B Thimmapaya
Journal of Biological Chemistry 270 (7), 3454-3461, 1995
841995
Requirement of PKR dimerization mediated by specific hydrophobic residues for its activation by double-stranded RNA and its antigrowth effects in yeast
RC Patel, GC Sen
Molecular and cellular biology 18 (12), 7009-7019, 1998
831998
AP-1 mediated transcriptional repression of matrix metalloproteinase-9 by recruitment of histone deacetylase 1 in response to interferon β
ML Mittelstadt, RC Patel
Public Library of Science 7 (8), e42152, 2012
822012
Stress-induced phosphorylation of PACT reduces its interaction with TRBP and leads to PKR activation
M Singh, D Castillo, CV Patel, RC Patel
Biochemistry 50 (21), 4550-4560, 2011
792011
The carboxy-terminal, M3 motifs of PACT and TRBP have opposite effects on PKR activity
V Gupta, X Huang, RC Patel
Virology 315 (2), 283-291, 2003
772003
Role of the amino-terminal residues of the interferon-induced protein kinase in its activation by double-stranded RNA and heparin
RC Patel, P Stanton, GC Sen
Journal of Biological Chemistry 269 (28), 18593-18598, 1994
751994
The PKR activator, PACT, becomes a PKR inhibitor during HIV-1 replication
G Clerzius, E Shaw, A Daher, S Burugu, JF Gélinas, T Ear, L Sinck, ...
Retrovirology 10, 1-15, 2013
632013
Regulation of vascular smooth muscle proliferation by heparin: inhibition of cyclin-dependent kinase 2 activity by p27kip1
S Fasciano, RC Patel, I Handy, CV Patel
Journal of Biological Chemistry 280 (16), 15682-15689, 2005
592005
Essential role of PACT-mediated PKR activation in tunicamycin-induced apoptosis
M Singh, V Fowlkes, I Handy, CV Patel, RC Patel
Journal of molecular biology 385 (2), 457-468, 2009
582009
Increased interaction between PACT molecules in response to stress signals is required for PKR activation
M Singh, RC Patel
Journal of cellular biochemistry 113 (8), 2754-2764, 2012
572012
Altered activation of protein kinase PKR and enhanced apoptosis in dystonia cells carrying a mutation in PKR activator protein PACT
LS Vaughn, DC Bragg, N Sharma, S Camargos, F Cardoso, RC Patel
Journal of Biological Chemistry 290 (37), 22543-22557, 2015
562015
Homeobox gene HOXA9 inhibits nuclear factor-kappa B dependent activation of endothelium
CM Trivedi, RC Patel, CV Patel
Atherosclerosis 195 (2), e50-e60, 2007
492007
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