| Parallel synthesis of 3-aminoimidazo [1, 2-a] pyridines and pyrazines by a new three-component condensation C Blackburn, B Guan, P Fleming, K Shiosaki, S Tsai Tetrahedron letters 39 (22), 3635-3638, 1998 | 456 | 1998 |
| Substrate-based design of the first class of angiotensin-converting enzyme-related carboxypeptidase (ACE2) inhibitors NA Dales, AE Gould, JA Brown, EF Calderwood, B Guan, CA Minor, ... Journal of the American Chemical Society 124 (40), 11852-11853, 2002 | 215 | 2002 |
| A novel dealkylation affording 3-aminoimidazo[1,2-a]pyridines: access to new substitution patterns by solid-phase synthesis C Blackburn, B Guan Tetrahedron letters 41 (10), 1495-1500, 2000 | 107 | 2000 |
| Identification and characterization of 4-aryl-3,4-dihydropyrimidin-2(1H)-ones as inhibitors of the fatty acid transporter FATP4 C Blackburn, B Guan, J Brown, C Cullis, SM Condon, TJ Jenkins, ... Bioorganic & medicinal chemistry letters 16 (13), 3504-3509, 2006 | 98 | 2006 |
| Design, synthesis, and progress toward optimization of potent small molecule antagonists of CC chemokine receptor 8 (CCR8) S Ghosh, A Elder, J Guo, U Mani, M Patane, K Carson, Q Ye, R Bennett, ... Journal of medicinal chemistry 49 (9), 2669-2672, 2006 | 45 | 2006 |
| Bruton's tyrosine kinase inhibitors M Bui, P Conlon, JH Cuervo, DA Erlanson, FAN Junfa, B Guan, ... US Patent 8,785,440, 2014 | 41 | 2014 |
| Design, synthesis, and evaluation of naphthalene-sulfonamide antagonists of human CCR8 TJ Jenkins, B Guan, M Dai, G Li, TE Lightburn, S Huang, BS Freeze, ... Journal of medicinal chemistry 50 (3), 566-584, 2007 | 41 | 2007 |
| Heteroaryl Btk inhibitors M Bui, P Conlon, DA Erlanson, FAN Junfa, B Guan, BT Hopkins, ... US Patent 9,029,359, 2015 | 39 | 2015 |
| ACE-2 modulating compounds and methods of use thereof SL Acton, TD Ocain, AE Gould, NA Dales, B Guan, JA Brown, M Patane, ... US Patent 7,045,532, 2006 | 29 | 2006 |
| Heterocyclic compounds useful as RAF kinase inhibitors J Cossrow, B Guan, A Ishchenko, JH Jones, G Kumaravel, A Lugovskoy, ... US Patent 7,968,536, 2011 | 26 | 2011 |
| Aryl sulfonamides useful as inhibitors of chemokine receptor activity M Dai, B Guan, RA Bennett, DF Burdi, S Ghosh, G Li, C Minor, TJ Jenkins US Patent 7,491,827, 2009 | 22 | 2009 |
| Compounds useful as Raf kinase inhibitors W Chen, J Cossrow, L Franklin, B Guan, JH Jones, G Kumaravel, B Lane, ... US Patent 8,293,752, 2012 | 20 | 2012 |
| Mechanism investigation for poloxamer 188 raw material variation in cell culture H Peng, A Ali, M Lanan, E Hughes, K Wiltberger, B Guan, S Prajapati, ... Biotechnology Progress 32 (3), 767-775, 2016 | 16 | 2016 |
| CCR8 inhibitors B Guan, C Minor, M Dai, S Ghosh, TJ Jenkins, G Li, DF Burdi, RA Bennett US Patent 7,378,525, 2008 | 16 | 2008 |
| ACE-2 inhibiting compounds and methods of use thereof SL Acton, TD Ocain, AE Gould, NA Dales, B Guan, JA Brown US Patent 6,632,830, 2003 | 16 | 2003 |
| CCR8 inhibitors M Dai, TJ Jenkins, B Guan, S Ghosh, C Minor US Patent 7,329,755, 2008 | 13 | 2008 |
| Bruton's tyrosine kinase inhibitors M Bui, P Conlon, JH Cuervo, DA Erlanson, FAN Junfa, B Guan, ... US Patent 9,790,229, 2017 | 9 | 2017 |
| Heterocyclic tyrosine kinase inhibitors BT Hopkins, D Scott, P Conlon, TJ Jenkins, N Powell, B Guan, JH Cuervo, ... US Patent 9,273,028, 2016 | 9 | 2016 |
| Bruton'S tyrosine kinase inhibitors M Bui, P Conlon, JH Cuervo, DA Erlanson, FAN Junfa, B Guan, ... US Patent 9,249,146, 2016 | 9 | 2016 |
| Characterization of poloxamers by reversed-phase liquid chromatography B Guan, A Ali, H Peng, W Hu, LR Markely, S Estes, S Prajapati Analytical methods 8 (13), 2812-2819, 2016 | 7 | 2016 |
Peter TumminoChief Scientific Officer, Nimbus TherapeuticsVerified email at nimbustx.com
