Follow
Jan M van Deursen
Jan M van Deursen
Unknown affiliation
No verified email - Homepage
Title
Cited by
Cited by
Year
Clearance of p16Ink4a-positive senescent cells delays ageing-associated disorders
DJ Baker, T Wijshake, T Tchkonia, NK LeBrasseur, BG Childs, ...
Nature 479 (7372), 232-236, 2011
35732011
The role of senescent cells in ageing
JM Van Deursen
Nature 509 (7501), 439-446, 2014
25332014
Naturally occurring p16Ink4a-positive cells shorten healthy lifespan
DJ Baker, BG Childs, M Durik, ME Wijers, CJ Sieben, J Zhong, ...
Nature 530 (7589), 184-189, 2016
23962016
AML1, the target of multiple chromosomal translocations in human leukemia, is essential for normal fetal liver hematopoiesis
T Okuda, J Van Deursen, SW Hiebert, G Grosveld, JR Downing
Cell 84 (2), 321-330, 1996
22971996
Cellular senescence in aging and age-related disease: from mechanisms to therapy
BG Childs, M Durik, DJ Baker, JM Van Deursen
Nature medicine 21 (12), 1424-1435, 2015
19062015
Cellular senescence and the senescent secretory phenotype: therapeutic opportunities
T Tchkonia, Y Zhu, J Van Deursen, J Campisi, JL Kirkland
The Journal of clinical investigation 123 (3), 966-972, 2013
16882013
Lack of IL-4-induced Th2 response and IgE class switching in mice with disrupted State6 gene
K Shimoda, J van Deursent, MY Sangster, SR Sarawar, RT Carson, ...
Nature 380 (6575), 630-633, 1996
16311996
Stat5a and Stat5b proteins have essential and nonessential, or redundant, roles in cytokine responses
S Teglund, C McKay, E Schuetz, JM Van Deursen, D Stravopodis, ...
Cell 93 (5), 841-850, 1998
15281998
Requirement for Stat4 in interleukin-12-mediated responses of natural killer and T cells
WE Thierfelder, JM van Deursen, K Yamamoto, RA Tripp, SR Sarawar, ...
Nature 382 (6587), 171-174, 1996
14651996
Jak2 is essential for signaling through a variety of cytokine receptors
E Parganas, D Wang, D Stravopodis, DJ Topham, JC Marine, S Teglund, ...
Cell 93 (3), 385-395, 1998
13611998
Fat tissue, aging, and cellular senescence
T Tchkonia, DE Morbeck, T Von Zglinicki, J Van Deursen, J Lustgarten, ...
Aging cell 9 (5), 667-684, 2010
12132010
Local clearance of senescent cells attenuates the development of post-traumatic osteoarthritis and creates a pro-regenerative environment
OH Jeon, C Kim, RM Laberge, M Demaria, S Rathod, AP Vasserot, ...
Nature medicine 23 (6), 775-781, 2017
12102017
Senescent intimal foam cells are deleterious at all stages of atherosclerosis
BG Childs, DJ Baker, T Wijshake, CA Conover, J Campisi, ...
Science 354 (6311), 472-477, 2016
10132016
Senescent cells: an emerging target for diseases of ageing
BG Childs, M Gluscevic, DJ Baker, RM Laberge, D Marquess, ...
Nature reviews Drug discovery 16 (10), 718-735, 2017
9512017
Clearance of senescent glial cells prevents tau-dependent pathology and cognitive decline
TJ Bussian, A Aziz, CF Meyer, BL Swenson, JM van Deursen, DJ Baker
Nature 562 (7728), 578-582, 2018
9332018
Senescence and apoptosis: dueling or complementary cell fates?
BG Childs, DJ Baker, JL Kirkland, J Campisi, JM Van Deursen
EMBO reports 15 (11), 1139-1153, 2014
8742014
BubR1 insufficiency causes early onset of aging-associated phenotypes and infertility in mice
DJ Baker, KB Jeganathan, JD Cameron, M Thompson, S Juneja, ...
Nature genetics 36 (7), 744-749, 2004
8562004
MDC1 maintains genomic stability by participating in the amplification of ATM-dependent DNA damage signals
Z Lou, K Minter-Dykhouse, S Franco, M Gostissa, MA Rivera, A Celeste, ...
Molecular cell 21 (2), 187-200, 2006
8192006
Defective lymphoid development in mice lacking Jak3
T Nosaka, JMA Van Deursen, RA Tripp, WE Thierfelder, BA Witthuhn, ...
Science 270 (5237), 800-802, 1995
7861995
Stat5 is required for IL-2-induced cell cycle progression of peripheral T cells
R Moriggl, DJ Topham, S Teglund, V Sexl, C McKay, D Wang, ...
Immunity 10 (2), 249-259, 1999
6871999
The system can't perform the operation now. Try again later.
Articles 1–20