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Ismail Syed
Ismail Syed
Beth Israel Deaconess Medical Center, Harvard Medical School
Verified email at bidmc.harvard.edu
Title
Cited by
Cited by
Year
Discovery of a Class of Endogenous Mammalian Lipids with Anti-Diabetic and Anti-inflammatory Effects
MM Syed, Ismail Yore, PM Moraes-Vieira, T Zhang, MA Herman, ...
Cell 159 (2), 318-332, 2014
7462014
RBP4 Activates Antigen-Presenting Cells, Leading to Adipose Tissue Inflammation and Systemic Insulin Resistance
PM Moraes-Vieira, MM Yore, PM Dwyer, I Syed, P Aryal, BB Kahn
Cell Metabolism 19 (3), 512-526, 2014
2702014
Palmitic Acid Hydroxystearic Acids Activate GPR40, Which Is Involved in Their Beneficial Effects on Glucose Homeostasis
I Syed, J Lee, PM Moraes-Vieira, CJ Donaldson, A Sontheimer, P Aryal, ...
Cell Metabolism 27 (2), 419-427. e4, 2018
1572018
TIAM1–RAC1 signalling axis-mediated activation of NADPH oxidase-2 initiates mitochondrial damage in the development of diabetic retinopathy
RA Kowluru, A Kowluru, R Veluthakal, G Mohammad, I Syed, JM Santos, ...
Diabetologia 57, 1047-1056, 2014
1362014
Absence of Carbohydrate Response Element Binding Protein in Adipocytes Causes Systemic Insulin Resistance and Impairs Glucose Transport
A Vijayakumar, P Aryal, J Wen, I Syed, RP Vazirani, PM Moraes-Vieira, ...
Cell Reports 21 (4), 1021-1035, 2017
1342017
Vitamin D deficiency-induced muscle wasting occurs through the ubiquitin proteasome pathway and is partially corrected by calcium in male rats
M Bhat, R Kalam, SSYH Qadri, S Madabushi, A Ismail
Endocrinology 154 (11), 4018-4029, 2013
1262013
Increased phagocyte-like NADPH oxidase and ROS generation in Type 2 diabetic ZDF rat and human islets: role of Rac1–JNK1/2 signaling pathway in mitochondrial dysregulation in …
I Syed, CN Kyathanahalli, B Jayaram, S Govind, CJ Rhodes, RA Kowluru, ...
Diabetes 60 (11), 2843-2852, 2011
1172011
A LC-MS–based workflow for measurement of branched fatty acid esters of hydroxy fatty acids
T Zhang, S Chen, I Syed, M Ståhlman, MJ Kolar, EA Homan, Q Chu, ...
Nature protocols 11 (4), 747-763, 2016
732016
Phagocyte-like NADPH oxidase promotes cytokine-induced mitochondrial dysfunction in pancreatic β-cells: evidence for regulation by Rac1
W Subasinghe, I Syed, A Kowluru
American Journal of Physiology-Regulatory, Integrative and Comparative …, 2011
732011
Tiam1/Rac1 signaling pathway mediates palmitate-induced, ceramide-sensitive generation of superoxides and lipid peroxides and the loss of mitochondrial membrane potential in …
I Syed, B Jayaram, W Subasinghe, A Kowluru
Biochemical pharmacology 80 (6), 874-883, 2010
712010
Arf nucleotide binding site opener [ARNO] promotes sequential activation of Arf6, Cdc42 and Rac1 and insulin secretion in INS 832/13 β-cells and rat islets
B Jayaram, I Syed, CN Kyathanahalli, CJ Rhodes, A Kowluru
Biochemical pharmacology 81 (8), 1016-1027, 2011
652011
PAHSAs attenuate immune responses and promote β cell survival in autoimmune diabetic mice
I Syed, MFR de Celis, JF Mohan, PM Moraes-Vieira, A Vijayakumar, ...
The Journal of clinical investigation 129 (9), 3717-3731, 2019
642019
Stereochemistry of Endogenous Palmitic Acid Ester of 9-Hydroxystearic Acid and Relevance of Absolute Configuration to Regulation
AT Nelson, MJ Kolar, Q Chu, I Syed, BB Kahn, A Saghatelian, D Siegel
Journal of the American Chemical Society 139 (13), 4943-4947, 2017
642017
Branched Fatty Acid Esters of Hydroxy Fatty Acids Are Preferred Substrates of the MODY8 Protein Carboxyl Ester Lipase
MJ Kolar, SS Kamat, WH Parsons, EA Homan, T Maher, OD Peroni, ...
Biochemistry 55 (33), 4636-4641, 2016
612016
Protein Farnesylation–Dependent Raf/Extracellular Signal–Related Kinase Signaling Links to Cytoskeletal Remodeling to Facilitate Glucose-Induced Insulin Secretion in Pancreatic …
A Kowluru, R Veluthakal, CJ Rhodes, V Kamath, I Syed, BJ Koch
Diabetes 59 (4), 967-977, 2010
602010
Phagocyte-like NADPH oxidase generates ROS in INS 832/13 cells and rat islets: role of protein prenylation
I Syed, CN Kyathanahalli, A Kowluru
American Journal of Physiology-Regulatory, Integrative and Comparative …, 2011
492011
Methodological Issues in Studying PAHSA Biology: Masking PAHSA Effects
I Syed, J Lee, OD Peroni, MM Yore, PM Moraes-Vieira, A Santoro, ...
Cell metabolism 28 (4), 543-546, 2018
442018
Distinct biological activities of isomers from several families of branched fatty acid esters of hydroxy fatty acids (FAHFAs)
P Aryal, I Syed, J Lee, R Patel, AT Nelson, D Siegel, A Saghatelian, ...
Journal of Lipid Research 62, 2021
372021
Adipose tissue dysfunction is associated with low levels of the novel Palmitic Acid Hydroxystearic Acids
A Hammarstedt, I Syed, A Vijayakumar, B Eliasson, S Gogg, BB Kahn, ...
Scientific reports 8 (1), 15757, 2018
362018
Overexpressing the novel autocrine/endocrine adipokine WISP2 induces hyperplasia of the heart, white and brown adipose tissues and prevents insulin resistance
JR Grünberg, JM Hoffmann, S Hedjazifar, A Nerstedt, L Jenndahl, J Elvin, ...
Scientific reports 7 (1), 43515, 2017
362017
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